Ready, set, mutate?and may the best microbe win
... molecular and atomic level. Shamoo said the most promising finding is the fact that the follow-up test produced precisely the same mutant genes. "The duplicate study suggests that the pathways of molecular adaptation are reproducible and not highly variable under identical conditions," Shamoo said. ...Cells use mix-and-match approach to tailor regulation of genes
...werful new tool to narrow their search to the most promising candidates." ...First-ever genomic test predicts which lung cancer patients need chemotherapy to live
...ute for Genome Sciences & Policy. The test's promising results have initiated a landmark multi-center clinical trial, to be led by Duke investigators next year. Patients with early-stage non-small cell lung cancer, the most common and fatal form of cancer, will receive the genomic test and its results wi...Unique dual target specificity of kinase inhibitor key for success against cancer
...lear, this kinase family represents a rational and promising target for design of new cancer therapeutics. Dr. William A. Weiss, from the Department of Neurology at the University of California, San Francisco and coworkers sought to identify which PI3 kinase isoforms are critical for growth and progression of ...Adult stem cell research at UB targets damaged hearts
...out initial stem-cell transplantation studies with promising results," said Lee. "Additional studies will be needed to determine whether and how stem cell populations isolated from aged animals may be used. "In the long-term, the translation between the MSC-based therapy in the porcine hibernating myocardiu...A sweet solution for Alzheimer's disease?
...-Hyslop said. "There are many things that are very promising when done in animal models that turn out to either not work in humans or to have unexpected toxicity." A public Canadian company called Transition Therapeutics has regulatory approval for clinical trials of scyllo-inositol in humans with Alzheimer's...New research promising for improving brain cell survival after brain injury
... such a drug will be available, this research is a promising step forward in the development of an effective treatment for traumatic brain injury," Prof Tan said. ...Compound in dairy products targets diabetes
...s conjugated linoleic acids (CLA), have also shown promising results in human trials, signaling a new way of potentially treating the disease without synthetic drugs. "The compounds are predominantly found in dairy products such as milk, cheese and meat, and are formed by bacteria in ruminants that take lin...New research: Soy germ isoflavones reduce bone loss
...h long-term hormone replacement therapy use. This promising research is another step in advancing soy germ isoflavones as a safe, effective option," said Jocelyn Mathern, RD and Technical Specialist, Acatris. The study aimed to examine the effects of a high-dose supplementation of soy germ isoflavones (84 an...Nanotechnology being used to improve biocompatibility of human prosthetics and implants
...in orthopaedic and dental applications. The most promising form of CP are hydroxyapatite (Ca 10 (PO 4 ) 6 (OH) 2 , HA) coatings used to promote rapid bone remodelling on the titanium alloy implants. It is well known that the microstructure of these coatings significantly influences their mechanical propertie...OHSU study says stem cell 'fusion' occurs in tumors
...e potential to give rise to malignant cancer. One promising result could be in better understanding the careful balance between rapid and effective regeneration after tissue injury, and minimizing the risk of cancer. This balance can be examined in mouse models of inflammatory bowel disease, where, like human...'Smart' genetic therapy helps the body to heal itself
...th van Deutekom in his department has discovered a promising genetic therapy for Duchenne muscular dystrophy (DMD). Using anti-sense molecules (small pieces of synthetic RNA that can bind to specific sequences in the parts of the gene that code for the disease), the processing of the genetic code for dystrop...Robots manipulating animal behaviour
...nts ?a two-way interaction that is unique and very promising for sciences such as biology and robotics." Not only did the insbots act like and interact with the insects, they even succeeded in changing the roaches' behaviour. For example, the darkness-loving insects followed their artificial cousins towards ......ion don't think of rice as offering an exciting or promising career, so they focus on other industries and other careers," says Robert S. Zeigler, director general of the Philippines-based International Rice Research Institute (IRRI). IRRI, together with the Thai Rice Foundation under Royal Patronage (TRF) and...New technology enables faster, more efficient cell harvest: Cell therapy meeting study
...rative medicine, which includes cell therapy, is a promising area of scientific research with application in the treatment and cure of a rapidly expanding list of diseases and injuries. Scientists believe cell-based therapies could be used to repair damaged heart muscle following a heart attack, replace skin ......rative medicine, which includes cell therapy, is a promising area of scientific research with application in the treatment and cure of a rapidly expanding list of diseases and injuries. Scientists believe cell-based therapies could be used to repair damaged heart muscle following a heart attack, replace skin ...Clot-busting drug helps revive cardiac arrest patients
... will lead the way for additional research on this promising new approach." Fifty patients who did not respond to treatment with ACLS interventions were given the clot-buster tenecteplase, known medically as a fibrinolytic agent. Spontaneous circulation returned in 26 percent of these patients. Four percent...Study defines effective microbicide design for HIV/AIDS prevention
... demonstrated their new tool by applying it to the promising microbicide Cyanovirin-N, a protein with anti-HIV activity that has been well documented by other scientists. "Our results suggest HIV neutralization is achievable if coating thicknesses on the order of 100 microns remain in place after sex," Geon...New angiogenesis finding may help fight cancer growth
...d to heal wounds, blocking angiogenesis could be a promising way to halt tumor growth. Also in June, the FDA approved a compound that inhibits VEGF for treating colon cancer, the second-leading cause of cancer death in the United States. The VEGF-inhibitor reduces the formation of blood vessels, helping starve...Combination therapy shows promising results in patients with advanced lung cancer
...d therapy with a common anti-inflammatory produced promising results in patients with advanced lung cancer, res..."I think the results of this early phase study are promising and I anticipate we'll have a better understanding of Tarceva resistance in the near future," she sa...