Anti-inflammatory drug's potentially deadly side effect found to be rare
...e study of more than 3,000 patients who received a promising anti-inflammatory drug, natalizumab, that was linked to three cases of a serious brain infection in large clinical trials halted in early 2005. The new study found no new cases of progressive multifocal leukoencephalopathy (PML) and confirmed the th...Researches discover gene critical for protection against septic-shock-induced death
... failure during septic shock. Hence, Nrf2 can be a promising therapeutic target for attenuating septic-related deaths." According to Biswal, the findings provide a better understanding of the human body's defense mechanisms to sepsis and septic shock, and may provide clues to designing novel therapies that c...First direct mechanical communication of mitochondria, cardiomyocyte nucleus shown
...ies are needed to explore this very intriguing and promising field of knowledge," he concluded. In the experiment, the researchers found that in an artificial medium mimicking the cytosol, 10 micro-molar of valinomycin (a potassium ionophore that induces mitochondrial matrix swelling) decreased nuclear volum...Science finds new fix for UV-damaged skin in arthritis treatment
...ical cosmetic applications of glucosamine, and the promising results." An International Consensus on Glucosamine Skin BenefitsIn early 2006, a group of leading dermatologists from around the world and Procter & Gamble Beauty scientists convened in Rome to review and discuss the glucosamine data. The pane...Study shows hope for ridding lakes of clawed invader
...o-pronged attack, says Carpenter, has yielded very promising results. "It seems to be working. The aquatic plants are back. That's good because that's fish habitat, and the fish populations are returning to what they were before the rusty got into the lake sometime in the 1980s," says Carpenter. The two-pr...Trial success for diabetic nerve therapy
...ment for nerve damage caused by diabetes has shown promising results in preclinical and early patient trials. The University of Manchester team has discovered that injection of a novel therapeutic that works by stimulating a person's genes may prevent nerve damage ?primarily to the hands and feet ?caused by t...Tramiprosate (Alzhemed? preclinical results published in Neurobiology of Aging
... severity of AD. The Aβ-peptide is one of the most promising targets for the development of AD therapies. "This scientific paper highlights the potential benefits of Alzhemed?" said Dr. Andreas Orfanos, Neurochem's Executive Vice President, Strategic Planning and Scientific Affairs. "These preclinical resul...New potential drug target in tuberculosis
...fatty acids onto other proteins. "LipB is a very promising drug target," Wilmanns says, "because it belongs to a vital pathway. Unlike other organisms M. tuberculosis has no backup mechanism that could take over LipB's role. This means that an inhibitor blocking its active site would shut down key processes ...Speeding discovery of the 'human cancer genome'
...omparisons between species, the researchers report promising finds: one of the research teams identified two genes that can--in some circumstances--conspire to produce liver cancer, while the second uncovered a gene important to the spread of melanoma, the most serious form of skin cancer. Such functionally im...Radioactive scorpion venom for fighting cancer
... physicists are establishing safe procedures for a promising experimental brain-cancer therapy which uses a rad...t science fiction, but rather to help to develop a promising new therapy for brain cancer. The venom of the yellow Israeli scorpion preferentially attaches to ...Parkinson's disease mechanism discovered
...According to the researchers, the findings offer a promising opportunity for developing new drugs to treat the underlying causes of Parkinson's disease and related neurodegenerative disorders. The research team, which included Howard Hughes Medical Institute investigators Susan L. Lindquist and Nancy M. Bonin...Rehydrate -- your RNA needs it
...elves play critical roles in living cells and show promising medical applications. The researchers' findings will be published online in the Proceedings of the National Academy of Sciences (PNAS) this week. RNA enzymes, also known as ribozymes, accelerate chemical reactions inside cells, just as their bett...Stanford doctors advance in bid to turn mice stem cells into blood vessels
... research is to bring together two of today's most promising areas of medical investigation: stem cell research and tissue engineering. Tissue engineering, the growth of organs and tissues outside the body for replacement, has achieved successful transplantations of a variety of human tissues including skin an...Drug discovery team to explore newly discovered deep-sea reefs
...er deepwater reefs near Miami and Bimini, and some promising potential disease treatments, so we're very excite...e to explore those seafloor areas that appear most promising based on their sonar map contours. As this "ground truthing" work progresses, the team will be able ...Bubbles go high-tech to fight tumors
...a new technique in embolotherapy. What makes it so promising is that the technique allows doctors to control exactly where the bubbles are formed, so blockage of blood flow to surrounding tissue is minimal, said Joseph Bull, assistant professor of biomedical engineering at U-M. The research of Bull and colla......e to explore those seafloor areas that appear most promising based on their sonar map contours. As this "groun...nism samples and the identification of a number of promising potential drugs now in various stages of development for treating cancer, Alzheimer's disease, malar...CHAVI announces international search for genes affecting HIV response
...nces among people to point the way toward the most promising avenues for vaccine development," said David Goldstein, Ph.D., director of the Center for Population Genomics and Pharmacogenetics at the Duke Institute for Genome Sciences & Policy and director of CHAVI's host genetics research core. "We want to...Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent
...s per second to about 29 spikes per second. Two promising lines of research Colom and his fellow researchers at the University of Texas at Brownsville/Texas Southmost College are looking at two different approaches to stopping epilepsy. One group is taking the approach of making the neurons less excitable...H5N1 vaccine could be basis for life-saving stockpile
...er said. "So our success with ferrets is extremely promising news." Using reverse genetics, the team mixed genes from a safe, laboratory bird flu virus with a gene for the hemagglutinin (HA) protein from the H5N1 virus isolated in Hong Kong. The virus uses the HA proteins on its surface to infect cells in th...Scientists to employ Arctic ice and polar bears to protect diversity of world's crops
...er said. "So our success with ferrets is extremely promising news." Using reverse genetics, the team mixed genes from a safe, laboratory bird flu virus with a gene for the hemagglutinin (HA) protein from the H5N1 virus isolated in Hong Kong. The virus uses the HA proteins on its surface to infect cells in th...