Canine cancer vaccine program shows early promise
...mote chance that this would help their pet. After promising results from work done in collaboration with cancer specialists from Arizona, California, and Michigan, the school has hired a full-time technician to produce the existing vaccine. The vaccine being used now has undergone a few modifications designe...Carbon nanotube absorption measured in worms, cancer cells
...ed multi-walled carbon nanotubes---one of the most promising nanomaterials developed to date---with the carbon-14 radioactive isotope, which enabled the nanotubes to be tracked and quantified as they were absorbed into living cells. Researchers used cancer cells called HeLa cells, and also measured nanotube up...Melanoma vaccine strategy shows promise in laboratory experiments
...ating a vaccine to treat melanoma has demonstrated promising effectiveness in a new laboratory study led by researchers at The Wistar Institute. About a third of melanoma patients might benefit from such a vaccine. The study appears in the current issue of Cancer Research. In the study, the scientists used a ...Researchers get neurons and silicon talking
...he effect of drugs on neurons, to quickly discover promising avenues of research," says Professor Stefano Vassanelli, a molecular biologist with the University of Padua in Italy, and one of the partners in the NACHIP project, funded under the European Commission's Future and Emerging Technologies initiative of...Terahertz imaging may reduce breast cancer surgeries
A promising new technique to ensure complete tumor removal at breast cancer excision is introduced in the May issue of Radiology. Researchers used light waves in a newly explored region of the electromagnetic spectrum--the terahertz region--to examine excised b...... same thing could be done for men. "This is a very promising route to help young cancer patients undergoing chemotherapy," Dirk de Rooij of Utrecht University, Netherlands, told participants gathered at the first EuroSTELLS conference in Venice last month. The research team were delighted to find abundant bo...Researchers release new variety of asparagus
...earch associate at UCR, and I are working on other promising hybrids that are in trial at the moment, some of which may have even better yields than DePaoli." Currently, UCR is cultivating the DePaoli variety in a field near campus. The first test of the new variety, which involves evaluation of yield, spea...Scientists discover that widely available drug also helps fight kidney disease
...TOR, and strongly suggests that rapamycin may be a promising drug for treating PKD, explained Weimbs. "The fact that rapamycin is already clinically approved for other uses will facilitate future clinical trials of the drug." Co-authors on the paper with Weimbs are: Jonathan M. Shillingford and Seng Hui Low i...Study by Einstein researchers could lead to a novel strategy for treating obesity
... restoring fatty-acid levels in the brain may be a promising way to treat obesity. The study, published in the January 15th on-line edition of Nature Neuroscience, was led by Dr. Luciano Rossetti, director of the Diabetes Research Center at Einstein. (The paper will appear in print in the February issue.) The...Oh, rats! Designer animals reveal possible heart disease genes
...ar biologist at TIGR, notes that the data point to promising genes for salt-sensitive hypertension, among other conditions. The online database resulting from the study, dubbed TREX, is available free of charge at: http://pga.tigr.org/ . TIGR continues to study the panels of designer rat strains, and Lee hop...Cloned stem cells prove identical to fertilized stem cells
...ic cell nuclear transfer, therapeutic cloning is a promising approach to create individually customized cellular therapies for treating certain disorders. Demonstrated in mice but not in humans, it begins with stem cells derived from a cloned embryo. But if cloned embryos can't produce normal organisms, how ca...Potential heart benefit found in stem cells
... Stem cell transplantation is a controversial, yet promising option for a number of areas of the body that need repair or replacement. In fact, adult autologous (as in, using one's own cells) stem cells may be a novel approach for cardiac regeneration after heart attacks. In a closer look at their regenerati...U of S researchers develop new vaccine candidate against hepatitis C
... significant manner," he said. "This offers a very promising approach to prevent liver disease caused by the virus and to ultimately eliminate it from the body." About 20 per cent of people who contract HCV overcome the virus on their own. For those who develop chronic hepatitis, the immune system cannot cle...Legume compounds may help cancer treatment
...t show strong anti-angiogenic activity. "They are promising therapeutic molecules which clearly warrant further investigation," Professor Parish said. CILR Director Professor Peter Gresshoff said the current research success highlighted the importance of a critical mass of multidisciplinary biological scient...Data published in PNAS show antibodies can be made 10 times more toxic to cancer cells
... their role in the treatment of cancer, many other promising antibodies are sub-optimal for use as therapeutics. They just aren't powerful enough," said Bassil Dahiyat, Ph.D., President and CEO of Xencor. "The work we published in PNAS shows that specific changes to the Fc regions of antibodies have the poten...New Research Shows Artificial Light at Night Stimulates Breast Cancer Growth in Laboratory Mice
...e a higher rate of breast cancer. It also offers a promising new explanation for the epidemic rise in breast cancer incidence in industrialized countries like the United States. The National Cancer Institute and the National Institute of Environmental Health Sciences, agencies of the federal National Institut...Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure
... rhythm. The results in general demonstrated the promising utility of engineered tissue in the laboratory for studying the complex electrophysiological properties of the heart in both health and disease, they said. "Implanted defibrillators can protect many patients, but sometimes the devices instead accele...New method enables gene disruption in destructive fungal pathogen
...commented: "The new disruption method looks highly promising as a tool for functional genomic studies. The authors looked at over 20 genes and were able to produce transformants and inactivated genes or knock-outs in each experiment. In most cases, the efficiency of gene disruption was 100 percent, which repre...Proteins stop blood-vessel and tumor growth in mice
... the March issue of Cancer Research that a pair of promising proteins, known as fibulins 3 and 5, slow the grow...ing blood vessels from sprouting. The proteins are promising candidates for use in cancer therapy. "Healthy humans produce fibulin proteins, which regulate cel...... colleagues validate the p53 inhibitor, Mdm2, as a promising target for cancer therapies. The p53 tumor suppressor plays a critical role in cancer formation, and many anticancer strategies aim to activate p53 in order to curb tumor formation. Mdm2 is a key inhibitor of p53 and therefore an attractive target t...