Breast tumors in mice eradicated using cancer vaccine
...HER-2/neu molecule paves the way for applying this promising cancer vaccine approach to breast cancer. This research was funded by the Department of Defense and the National Cancer Institute. Co-authors are Reshma Singh and Mary E. Dominiecki, both from Penn, as well as Elizabeth M. Jaffee from the Johns Hop...Experimental shingles vaccine proves effective in nationwide study
...Co., Inc. (Whitehouse Station, NJ). "This is very promising news for older persons," says Stephen E. Straus, M.D., an infectious diseases specialist at NIAID and Director of the NIH National Center for Complementary and Alternative Medicine, who participated in the design, oversight and conduct of the trial. ...Corn grain mould used as pesticide
...3,000 isolates in all and have come across several promising strains," Sebastian Kiewnick states. "Now we'll soon be conducting the first field trials." Should they be successful, the team want to develop a quick and easy method for propagating the non-toxic mould for use en masse. There is no danger of addit...Grand Challenges in Global Health initiative funds Yale project
...m facing many vaccine developers. Some of the most promising vaccines for HIV and a range of other diseases are made from weakened versions of the infectious agent. These cannot be studied in human trials unless researchers are confident that they are safe. "A big need in the world of vaccine development is t...Fighting malaria by manipulating mosquitoes' sense of smell
...ilt-led research team is to pursue one of the most promising of these new avenues: developing chemical compound...d appear to be related to host selection. The most promising of these mixtures will be shipped to Wageningen University where their effects on the behavior of li...Updated data on novel HPV vaccine confirms efficacy in large population
Updated data from a study on a promising new vaccine against a pre-cancerous cervical virus shows superior efficacy in preventing cervical pre-cancers and non-invasive cervical cancer, according to a study presented today during the American Association for Cancer Research's 4th Annual Fron...Vaginal gel may provide a new approach to HIV prevention
...Director Anthony Fauci. "We need to build on these promising animal studies and move toward establishing the safety and effectiveness of combination microbicides in women." ...Emerging staph strains found to be increasingly deadly and deceptive
...e caused by antibiotic-resistant strains, and this promising work offers several new approaches." According to the Centers for Disease Control and Prevention, "recent reports of 'community-acquired' MRSA infections raise concern ?If MRSA becomes the most common form of Staphylococcus aureus in a community, it...Amphetamines reverse Parkinson's disease symptoms in mice
...in mammals. The current findings are particularly promising given the severity of symptoms in the mice completely lacking dopamine, said Gainetdinov. "We think that this new animal model provides a much more stringent test for potential drugs that might prove efficacious in patients with Parkinson's disease."...Scientists develop nanotech-laser treatment that kills cancer cells without harming healthy tissue
...ut ways to target cancer cells, and this is a very promising technique." Researchers at Rice University recently conducted a similar experiment on mice with cancerous tumors. Instead of carbon nanotubes, the Rice team injected the tumors with gold-coated nanoshells and exposed the animals to near-infrared lig...Gene therapy works in mice to prevent blindness that strikes boys
... able to repair retinal damage. The treatment has promising implications for other genetic eye diseases that involve the eye's ability to process light, including retinitis pigmentosa, which affects about 200,000 people in the United States and is one of the most common inherited causes of blindness in people...UK is first to administer new anti-clotting technology
...first of its kind. "This class of drugs is a very promising technology that allows for the development of 'designer' drugs and their antidotes simultaneously," said Dr. Steven R. Steinhubl, the study's principal investigator at UK and director of cardiovascular education and clinical research at the Gill Hear...PLoS Medicine publishes first trial of effect of male circumcision on HIV infection
..., UNAIDS emphasized that "although the trial shows promising protective effects of adult male circumcision in HIV acquisition, more research is needed to confirm the reproducibility of the findings and of this trial and whether or not the results have more general application." Furthermore, adult circumcisi...A bug's life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist
...practical implications," notes Wernegreen. "A very promising area of endosymbiont research is the manipulation of these bacteria to control host populations in the field." ...Living anti-HIV gel shows early promise
...t be assessed. Although the approach has produced promising results in mice, trials on monkeys exposed to HIV or the primate equivalent (SIV) will have to be successful before the bacteria can be tested in people. "It is a fascinating concept," says Harold Kessler, associate director of the Infectious Disease...Natural compound from 'pond scum' shows potential activity against Alzheimer's
...ural products have been increasingly found to be a promising source of drug candidates for fighting a variety o... of Alzheimer's, the researchers say. As with any promising structure, it could be many years before the new compound is tested as a drug candidate in humans, t...A new window into structural plasticity in the adult visual cortex
...f specific neurons in a local pathway should yield promising results. ...Small molecule inhibitor of cholera discovered
... and cause disease. They then showed that the most promising compound prevented cholera bacteria from setting up an infection when introduced into the digestive tract of mice. Since most disease-causing organisms use elaborate virulence factors such as toxins to do their damage, the new approach should be wi...NIAID researchers show how promising TB drug works
...tional Institutes of Health, have determined how a promising drug candidate attacks the bacterium that causes tuberculosis (TB). Published online this week in Proceedings of the National Academy of Sciences, the finding may help scientists optimize the drug candidate, PA-824, which targets Mycobacterium tuberc...Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
...llosa. Early trials using her approach have looked promising in animal models of both of these diseases. "I think our approach has a lot of potential to overcome issues that have slowed the field of gene therapy," Calos said. Calos said her approach has two advantages: one is that in her method the gene gets...