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Tag: "promising" at biology news

Why were the HIV prevention trials in commercial sex workers abandoned?

One promising approach to help stem the global HIV epidemic is to give commercial sex workers an HIV medication (such as the drug tenofovir) before they have high risk sex in the hope of reducing their chances of becoming infected, an approach called "pre-exposure...

Slipping past the blood brain barrier: Research shows potential treatment for brain cancer

.... Schally, Ph.D. Dr. Banks said the findings are promising because they show a way to get drugs into the brain to treat cancer. "There are times when there's a big difference between an animal model and the human condition. In terms of getting drugs across the blood brain barrier to fight cancer, there's n...

Chemical 'band-aid' prevents heart failure in mice with muscular dystrophy

...trophin, and the first study to demonstrate a new, promising approach to repair the damage. The study's authors emphasize, however, that several years of additional animal research will be required before the treatment could be tested in human patients. "Most people think of the heart as a pump," explains Met...

Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease

...on's disease. The interim UPDRS scores are highly promising and, if they are borne out with additional data, would be comparable to results seen with STN Deep Brain Stimulation. Unlike deep brain stimulation, however, our gene therapy approach is much simpler, can be carried out entirely under local anesthes...

Discovery of T-cell 'traffic control' boosts new drug promise

...mp healthy tissue. The new research explains how a promising experimental drug treats the autoimmune disease mu...he paper. They think this mechanism underlies the promising clinical trial results of a new drug against multiple sclerosis (MS) recently reported by other rese...

Proposal would allow wild animals to roam North America

...large tracts of private land are probably the most promising places to start, with each step carefully guided by the fossil record and the involvement of experts and research. "We are not advocating backing up a van and letting elephants and cheetahs out into the landscape," said Donlan. "All of this would be ...

Leading scientists rank endangered dolphins, porpoises most in need of immediate action

...tional Smart Gear Competition awarded a prize to a promising gillnet design concept using glowing ropes and stiffer nets that may help cetaceans see gillnets in order to avoid them and to escape if they do accidentally swim into the net. Species and populations designated in the report as among the top priori...

Canada's first embryonic stem cell lines

...tional Smart Gear Competition awarded a prize to a promising gillnet design concept using glowing ropes and stiffer nets that may help cetaceans see gillnets in order to avoid them and to escape if they do accidentally swim into the net. Species and populations designated in the report as among the top priori...

Novel targets found for the development of drugs to complement, or replace, statins

...tional Smart Gear Competition awarded a prize to a promising gillnet design concept using glowing ropes and stiffer nets that may help cetaceans see gillnets in order to avoid them and to escape if they do accidentally swim into the net. Species and populations designated in the report as among the top priori...

Virulizin granted orphan drug status in Europe

...tional Smart Gear Competition awarded a prize to a promising gillnet design concept using glowing ropes and stiffer nets that may help cetaceans see gillnets in order to avoid them and to escape if they do accidentally swim into the net. Species and populations designated in the report as among the top priori...

Visceral Leishmaniasis: Successful Vaccine Trial In Dogs

...linical trial currently under way (phase III), are promising for efforts to reduce transmission of leishmaniasis to humans. They also point to new lines of investigation for elaborating a possible human vaccine. An integrated research project, involving several IRD groups (2), has just been set up in India, to...

Huntington's cure in flies lays groundwork for broader treatment approaches

...s on single genetic pathways, then, Yin believes a promising alternative might be to simultaneously target a cocktail of gene-induced activities - all of which are set in motion, for example, by a single faulty gene. Yin has long worked in the area of "triplet expansion" diseases such as Huntington's and Frag...

Ancient DNA confirms single origin of Malagasy primates

... for ancient DNA studies from the tropics are less promising than those from higher latitudes, but when the results are potentially of such compelling interest, it's always worth a try," she said. ...

Columbia scientists develop cancer terminator viruses

...iral-based therapies for cancer. Two papers about promising research with genetically engineered viruses studied in mice, published today in the journals Cancer Research and the Proceedings of the National Academy of Sciences (PNAS), bring us significantly closer to this objective and the start of clinical tr...

Genomics researchers discover protein deficit that causes drug toxicity

...c medicine -- and now this finding is taking us in promising new directions because we believe our findings can be generalized to apply to many instances in the field." The finding helps explain what goes wrong under certain genetic conditions -- and suggests mechanisms which might help predict which genetic ...

Gradient guides nerve growth down spinal cord

...rging stem cell technologies, may provide the most promising current approach to nervous system regeneration. If Wnt proteins could be used to guide transplanted nerve cells -- or someday, embryonic stem cells -- to restore the connections between the body and the brain, "it could revolutionize treatment of pa...

Computers close in on protein structure prediction

... structures is carried out in the first stage, and promising locations are then explored in detail in the second stage. The first stage takes advantage of the fact that all amino acids have identical sections, which form the protein backbone. The computer adds a fuzzy picture of the protruding side chains t...

Researchers report breakthrough against world’s deadliest viruses

...se vaccines are safe and effective in monkeys is a promising indicator of their real potential for use in humans. "When you see the tragedies these viruses cause, it's very frustrating that we can't do more to help people," said Dr. Feldmann, who (along with Dr. Jones and others from PHAC) has been providing ...

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...function and their survival, thus holding out some promising avenues of treatment for human PAH. The team members believe that as in cancer, Survivin drives excessive cell growth in the PAH lung blood vessels. "The most intriguing aspect," explains principal researcher Evangelos Michelakis, "is we've shown fo...

'Cookbook recipes' would cure disease with nontoxic DNA delivery systems

... different ions." Gene therapy is one of the most promising strategies for developing cures for many hereditary and acquired diseases. Protocols have been approved for treating cancer, cystic fibrosis and neuromuscular disorders, for example, but delivering DNA to the proper location and getting the right amo...

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