Touching Molecules With Your Bare Hands
...just how evasion occurs, scientists can identify a promising target for controlling infection. Copyright: © 2005 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in ...'EuroVacc 02' HIV Vaccine Trial Begins
...for the clinical studies, "if this study generates promising results, EuroVacc intends to further evaluate the vaccines in larger clinical trials." Development background The vaccine candidates for the trial - DNA-HIV-C and NYVAC-HIV-C - were developed within the network European Vaccine Effort against HIV...Researchers test new therapy for advanced melanoma
... and the University of South Florida are testing a promising new therapy that prompts the immune system to aid in the fight against melanoma tumors. "This is a milestone clinical trial because it is the first time that electroporation is being used to deliver plasmid DNA in a gene therapy study in humans," sa...New vaccine means bye-bye to bacteria in the lung
...ed OprF, which had previously been recognized as a promising vaccine candidate. This region of the bacteria was expressed in the capsid area of the vector. Immunization of mice with this vaccine induced antibody production and protected the mice from exposure to a deadly dose of the bacteria. Importantly, the ...Understanding how bacteria communicate may help scientists prevent disease
...wo years of their tenure track as an investment in promising achievements in an important area. The institution matches the award. Much like a legislative body, some bacteria need a quorum, the presence of a critical number of individuals, before they can engage in particular activities. Typically these are a...Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT
...ecular signature." Resurrecting tricirbine may be promising for patients with ovarian cancer, for instance, because "40 percent of women with ovarian cancer have tumors with high levels of active Akt," according to Sebti. "To our knowledge, this is the first Akt inhibitor headed toward clinical trials," said...Revueltosaurus skeleton unearthed at Petrified Forest upsets dinosaur tale
... picked up the first fossils in March of 2004 at a promising outcrop in an area of the park that evidently had not been scouted by previous paleontologists, many of them from UC Berkeley. The campus has been involved in the park, located in northeastern Arizona near Holbrook, since John Muir first picked up fo...Agilent Technologies introduces high-capacity human protein removal system for proteomics research
... picked up the first fossils in March of 2004 at a promising outcrop in an area of the park that evidently had not been scouted by previous paleontologists, many of them from UC Berkeley. The campus has been involved in the park, located in northeastern Arizona near Holbrook, since John Muir first picked up fo...Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments
...e journal Science. "One of the keys to developing promising new therapies for debilitating neurodegenerative diseases lies in our understanding of how new neurons are created and integrated into mature brain tissue," Zhou said. "This protein is an attractive drug target for either boosting neuron-forming proc...Researchers develop promising new gene network analysis method
... The research is important because it describes a promising new tool for tracing human gene connections, a task critical for understanding and treating cancer and other diseases. Results appeared this week in the online edition of the Proceedings of the National Academy of Sciences. "Genes influence one anot...It's electric: Cows show promise as powerplants
...ty said. "Both studies suggest that cow waste is a promising fuel source. It's cheap and plentiful, and it may someday be a useful source of sustainable energy in developing parts of the world." While the source of energy for the fuel cell used in these studies is somewhat unique, microbial fuel cells aren't ...Using nanoparticles, in vivo gene therapy activates brain stem cells
...ioning brain cells, the nanoparticles also provide promising models for studying the genetic mechanisms of brain disease. "Until now, no non-viral technique has proven to be as effective as the viral vectors in vivo," said co-author Paras N. Prasad, Ph.D., executive director of the UB Institute for Lasers, P...Purdue scientists may have found key to halting spinal cord damage
...as established in 1987 both to develop and to test promising methods of treatment for spinal cord injuries. The center uses its close affiliation with the Department of Veterinary Clinical Sciences in the College of Veterinary Medicine to move basic laboratory methods into clinically meaningful veterinary test...Novel compounds show promise as safer, more potent insecticides
...nts. Targeting the ryanodine receptor may offer a promising alternative, researchers say. Ryanodine, a natural alkaloid discovered years ago in a species of tropical plant, has been used to study muscle physiology in a wide variety of organisms, including insects and mammals. Ryanodine receptors regulate musc...Scientists discover that three molecules may be developed into new Alzheimer's drugs
...rains of patients with Alzheimer's. The finding is promising news for the development of drugs for the disease. Ken Kosik, co-director of the Neuroscience Research Institute at the University of California, Santa Barbara, headed the effort to find these molecules. The results of the study are published in the...Discoveries by UAB and Florida scientists may help transplanted organs survive longer
...rejection by as much as several years. That's the promising implication of an animal study carried out by researchers at the University of Alabama at Birmingham (UAB) and the University of Florida (UF) published in today's (May 2) issue of Proceedings of the National Academy of Sciences. The research team re...Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
...rains of patients with Alzheimer's. The finding is promising news for the development of drugs for the disease. Ken Kosik, co-director of the Neuroscience Research Institute at the University of California, Santa Barbara, headed the effort to find these molecules. The results of the study are published in the...Compound might defeat African sleeping sickness, clinical trial beginning this month
... drug candidates in early development appear to be promising for treating late stage African sleeping sickness, which occurs when the parasite over time enters the brain." The new drug candidates are active because they can cross the blood-brain barrier, a biological wall that protects the nervous system natu...New mitochondrial DNA gene chip may be early cancer diagnosis tool
...veloped DNA sequencing chip. The mtDNA chips are a promising research tool for early clinical cancer diagnosis that may be faster, easier to interpret, and provide higher throughput than other methods. A paper describing the NCI-NIST work appears in the May issue of the Journal of Molecular Diagnostics. ...Nicotine triggers the same brain reward circuitry as opiates
... cues associated with smoking could lead to a more promising treatment regimen." ...