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Tag: "prolonged" at biology news

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...beneficial therapy and avoid the side effects of a prolonged and ineffective treatment," said Brian Ross, Ph.D., professor of radiology and biological chemistry at the U-M Medical School and a member of the U-M Comprehensive Cancer Center. In the study, 20 participants with brain tumors underwent diffusion MR...

Muscle-targeted gene therapy reverses rare muscular dystrophy in mice

...he replacement therapy, the infusions have already prolonged the lives of many babies with Pompe disease, Koeberl said. "A number of babies have been receiving enzyme replacement therapy for several years," said Koeberl. "They are walking, living longer, and meeting developmental milestones." Despite the ear...

World's largest rainforest drying experiment completes first phase

...tored in the soil that sustained the forest during prolonged dry seasons was depleted in the dry plot, the tree...Namely, how does the forest recover, or not, after prolonged drought? Although it is difficult to imagine a reversal of the current trend in rainforest drying, i...

Bone Density Recovers After Teens Stop Injected Contraceptive

...issued a “black box warning?for DMPA, stating that prolonged use of the drug may result in significant loss of bone density, that the loss is greater the longer the drug is administered and that bone density loss may not be completely reversible after discontinuation of the drug. The FDA warning states: “Depo...

Chemists identify immune system mechanism for methamphetamine binges

...umans, then it will help explain why addicts go on prolonged binges, requiring more frequent intake and ever-in...acity to have a decreased response to a drug after prolonged use. Increased drug tolerance raises the likelihood that a person will become addicted. "Right now,...

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

... among patients on HAART, who have less severe but prolonged immunosuppression. "Controlling the epidemic and ameliorating the suffering of persons living with HIV/AIDS are more urgent than ever," they write. "Continued study of cancer in people with HIV/AIDS will redound to give us clues about cancer etiology...

A frog's life is food for thought

... Cramp said. Little is known about the effects of prolonged food deprivation on the gut of animals that go without food for long periods. Ms Cramp's study is helping explain why animals such as the green-striped burrowing frog are able to gorge themselves on huge meals without overwhelming their digestive sys...

Buying Time Through Hibernation on Demand

...zens of documented cases exist of humans surviving prolonged hibernation-like states with no lingering physical or neurological damage. For example: * In May 1999, a female Norwegian skier was rescued after submersion in icy water for more than an hour. When rescued she was clinically dead with no heartbeat, ...

U-M team recovers ancient whale in Egyptian desert

...zens of documented cases exist of humans surviving prolonged hibernation-like states with no lingering physical or neurological damage. For example: * In May 1999, a female Norwegian skier was rescued after submersion in icy water for more than an hour. When rescued she was clinically dead with no heartbeat, ...

Youth With HIV Take More Risks After New Meds Introduced

...w drugs have successfully lowered virus levels and prolonged the lives of thousands of HIV patients. Although the new study does not prove that the introduction of HAART is the cause of increased risky behavior, "these findings indicate the need for continued attention to the issue of sexual risk and the impa...

Two chemicals boost immune cells' ability to fight HIV without gene therapy

... their production of a viral-fighting molecule and prolonged their power to kill HIV-infected cells. In this study, the scientists isolated immune cells from the blood of HIV-infected persons and cultured the cells with the chemical compounds. They were surprised to see that the compounds produced the same th...

Python a 'hearty' eater

... how remodeling of the heart occurs in adapting to prolonged exercise and in response to some diseases. The python does not eat frequently; it's more of a binge eater. James Hicks at the University of California, Irvine, together with his colleagues, discovered the snake's tell-tale heart undergoes drastic ph...

Natural Killers Could Lead to New Hepatitis Treatments

...ing. The studies showed that the presence of CXCR6 prolonged the NKT cells' survival. The researchers also found that the NKT cells of CXCR6-deficient mice showed a reduced patrolling, as well as a decreased severity of artificially induced hepatitis. “So, all the evidence we can obtain so far points to CXCR6...

Discovery of New Dopamine Action May Yield Alternative Psychiatric Drugs

...be more important than those earlier described for prolonged stimulation by dopamine, as would be the case in t...tute for Genome Sciences & Policy. Dopamine's prolonged effects might also apply to understanding the impact of sustained drug use on the brain, Caron added...

MIT engineers an anti-cancer smart bomb

...packing "nanocell" proved effective and safe, with prolonged survival, against two distinct forms of cancers--m...ed on different schedules: anti-angiogenics over a prolonged period and chemotherapy in cycles. "We designed the nanocell keeping these practical problems in mi...

New research could help us deliver genes for new bone formation

...lease of the gene delivery systems to generate the prolonged formation and development of bone tissue. The research teams are using the scaffold technology to develop therapeutic applications. They are investigating the most efficient and effective combinations of genes and delivery scaffold to trigger the hi...

Investigating 'brain shrinkage' in alcoholics

...impairment for weeks to months with sobriety, with prolonged sobriety these brain functions can show improvemen...ute to poor decisions and excessive drinking. With prolonged bouts of drinking, dependence may ensue along with neural systems damage, commonly affecting frontal...

A novel method to measure circadian cycles

...ng genetic causes), scientists have had to rely on prolonged behavioural observation. To screen for and identify circadian rhythm variations in humans, the required period of lengthy observation is prohibitively costly and labor intensive. Circumventing these technical limitations, Ueli Schibler and colleag...

Defect in gene causes 'neuralgic amyotrophy'

...ral nervous system. This heritable disease causes prolonged acute attacks of pain in the shoulder or arm, followed by temporary paralysis. Researchers from the Flanders Interuniversity Institute for Biotechnology (VIB) connected to the University of Antwerp, have uncovered a small piece of the molecular puzzl...

Monkeying around to improve organ transplantation

...cipient after kidney transplantation leads to very prolonged ?80 days?and perhaps even indefinite graft survival in three long-surviving animals without administration of additional immunosuppressive agents. This study shows for the first time that anergic T cells generated ex vivo suppress renal allograft rej...

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