proliferation 2 5

Tag: "proliferation" at biology news

Plant-derived molecules, genetic manipulation point to future chemoprevention methods

...yclooxygenase and nitric oxide expression, curbing proliferation and inducing apoptosis in human lung cancer cells....ME had already been proven effective in inhibiting proliferation and inducing apoptosis (programmed cellular death, a process that's often disrupted in cancer) in br...

Muscle and bone from an ink-jet printer

...able experience in using growth factors to control proliferation and differentiation in populations of “muscle-derived stem cells,?or MDSCs. Previous work by University of Pittsburgh researchers has demonstrated the ability of MDSCs to repair muscle in a model for Duchenne Muscular Dystrophy, improve cardiac funct...

Finding an answer to Darwin's Dilemma

... the amount of nutrients in the ocean and led to a proliferation of single-celled organisms that liberated oxygen through photosynthesis. This began an evolutionary radiation that led to complex communities of filter-feeding animals, then mobile bilateral animals, and ultimately to the Cambrian "explosion" of skel...

Rescuing injured hearts by enhancing regeneration

...ng only the p38 MAP kinase inhibitor had increased proliferation of cardiomyocytes, but no longer had improved hear...ctional improvement, but did not show as much cell proliferation as those receiving the p38 MAP kinase inhibitor. Rats receiving both agents had the greatest improve...

Studies find general mechanism of cellular aging

...ree seen in aging. According to Sharpless, islet proliferation persisted in p16INK4a -deficient animals as they aged, "almost as if they were younger animals." In mice with an excess of p16INK4a, "islet cells aged prematurely; they stopped dividing early." "This suggests that if we could attenuate p16INK4a expr...

How mammals fuel milk production may have implications for cancer

...ew scenarios in which metabolism isn’t tied to the proliferation or growth of cells,?Chodosh said. “The breast is an unusual organ that’s essentially a synthetic factory for milk. There’s nothing else like it.? During a typical 21-day course of lactation, a mouse will produce its entire body weight in lipid as ...

A valuable fly for research into disease

...s of cancer, and research into the development and proliferation of tumours will be a main topic of the conference. Ross Cagan, from the University of Washington, will present his recent research on a drug that has a direct effect on tumour progression. Cayetano González, from IRB Barcelona, will discuss his work ...

Harvard scientists identify compounds that stimulate stem cell growth in the brain

... play a role in inflammation and are regulators of proliferation of several cell types. When stem cells isolated from the brains of mouse embryos were exposed to LTB4 they proliferated and differentiated, giving rise to additional stem cells and to differentiated neurons with limited or absent capacity to divide....

Antibiotic inhibits cancer gene activity

...s responsible for turning on genes needed for cell proliferation and turning off genes that block proliferation. Uncontrolled proliferation is characteristic of cancer cells. The researchers developed a new screening system, based on a na...

MIT bioengineer advances survival, promise of adult stem cells

... certain growth factors encourage the survival and proliferation of bone marrow mesenchymal stem cells grown outside of the body. The work offers hope that one day, stem cells removed from a patient could be transplanted to an injury site and induced to grow into new, healthy tissue. The research appears in the...

Vitamin D deficiency widespread during pregnancy

..., an indicator of vitamin D status. Finding such a proliferation of vitamin D insufficiency in spite of prenatal multivitamin use is troubling, she noted, suggesting that higher dosages, differing vitamin formulations or a moderate increase in sunlight exposure might be necessary to boost vitamin D stores to healt...

Chemicals in brown algae may protect against skin cancer

...re strong indicators of inflammation, and for cell proliferation rates. Animals treated with BAPs showed lower ...82 percent. They also measured lower rates of cell proliferation in BAP-treated animals. "Both the oral and topical BAP treatment reduced COX-2 and prostaglandin...

Protein key to organ growth

...t the protein plays a major role in the growth and proliferation of cells, said researchers at Baylor College of Medicine in a report in current issue of the journal Nature. Work in his laboratory shows that TCTP plays a role in regulating Rheb (Ras homologue enriched in brain), a protein controlling growth and ...

Finnish scientists discovered a new approach to treat virus-induced lymphomas

...ch engage cellular signaling pathways, govern cell proliferation and modulate apoptosis. Majority of the PELs appear to have an intact TP53 gene suggesting that genetic alterations are not selected for during PEL tumorigenesis. The results of this study demonstrate binding of the KSHV latency associated antige...

How appetite-stimulating brain cells work overtime during fasting

...mediated UCP2 activation resulted in mitochondrial proliferation in the neurons, an event that was critical for the brain cells' increased excitability and consequent rebound feeding by the animals following food deprivation. "Our results indicate that this mechanism is critical in sustaining an increased firin...

'Marathon mice' elucidate little-known muscle type

...istics by driving the activity of genes that spark proliferation of mitochondria. The PGC-1â animals with more IIX muscle fibers showed a greater capacity for aerobic exercise, they found. Transgenic mice were able to run, on average, for 32.5 min to exhaustion, compared to 26 min for their normal littermates, ...

UCSD researchers discover variants of natural tumor suppressor

...in kinase B, a protein which controls cell growth, proliferation and survival. The new work describes a second f...ncer, we want the driver to brake, to prevent cell proliferation leading to tumor growth. But in diabetes, heart or neurological disease, where we want to promote c...

Growing nerve cells in 3-D dramatically affects gene expression

...ng to understand by studying these cells ?from the proliferation of cancer to the bacterial assault by antibiotics ?may play out differently. Studies indeed show differences in behavior between cells cultured in 2-D and in 3-D. Cells cultured in 3-D, for example, grow faster. Hoffman-Kim, an assistant professor...

Catching cancer's spread by watching hemoglobin

...blood vessels from existing ones—often signals the proliferation of tumors. This may make the technique convenient and powerful for helping to diagnose diseases such as melanoma, the deadliest form of skin cancer. The technique can image blood vessels up to a millimeter below the surface. Looking at blood vessels ...

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

...rphogenesis), oxidative stress, cell migration and proliferation and genes from fibroblasts and smooth muscle cells. According to Naftali Kaminski, M.D., director of the Simmons Center and director of the Lung Translational Genomics Center, division of pulmonary, allergy and critical care medicine, University ...

1 2 3 4 5 6