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Tag: "proliferation" at biology news

Brain size may depend upon how neural cells are cleaved

...isrupted. Now that the role of Gβγ in neural cell proliferation has been discovered, said Tsai, further studies will try to pinpoint how its signaling determines the orientation of spindles during mitosis, and thus the orientation of cell cleavage. "While this is basic research, we do know that this mechanism is...

Mosquito study shows new, faster way West Nile can spread

...that mammals such as horses may be involved in the proliferation of this virus. Direct transfer of virus from the infected mosquitoes that initially feed on them to others that feed on them afterwards, could significantly accelerate the spread of the disease," Higgs said. "Instead of only birds infecting mosquitoe...

Suppressing growth hormone in early adulthood may prevent cancer

...imals. Suppression of IGF-1 activity inhibits the proliferation of numerous cell types and cancers. "IGF-1 levels in the blood can be reduced by low-calorie diets, which could be a mechanism for the diet-cancer relationship," said Sonntag, whose work explores the neurobiology of aging. Previous studies in some a...

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...arget for selective intervention. "This makes the proliferation of lung blood vessels in this disease a 'form of cancer' or a form of neoplasia to be more precise, first proposed by Drs. Voelkel and Tuder from the University of Colorado. We've demonstrated for the first time that, like cancer, apoptosis is suppre...

Skull study sheds light on dinosaur diversity

... can tie the appearance of those features with the proliferation of wide gauge tracks everywhere in the fossil record at the end of the dinosaur era." Wilson wonders if the change in locomotion---from typical sauropod narrow-gauge walking to titanosaur wide-gauge walking---corresponded to lifestyle changes, such a...

Solution to 'legionella'

...stallations that are prone to be the focus for the proliferation of Legionnaires' disease. In order to validate the system, the team of INASMET-Tecnalia experts designed a refrigeration tower simulation within a biologically-isolated laboratory (P2 level). A wide range of trials were carried out in this isolated ...

miRNAs and musculature

...equired for mesodermal cell fate decisions or cell proliferation during embryogenesis, but rather, that it appears to act to reinforce and maintain cell identity during times of rapid growth. The authors find that, as in zebrafish, mouse and humans, Dmir-1 is specifically expressed in muscle cells. Furthermore,...

Eleven gene 'signature' reliably predicts cancer prognosis

...thway signature, which determines normal stem cell proliferation and which also consistently displays a stem cell-like expression profile in metastatic tumors in a mouse cancer model as well as metastatic tumors from prostate cancer patients. The results show that a stem cell-like expression profile of the 11-gene...

The making of a fat cell

...ut life. The first step in fat production involves proliferation of mesenchymal stem cells, followed by differentiation into fat cell precursors called preadipocytes. Mesenchymal stem cells can differentiate into various cell types, including bone, cartilage, muscle, nerve, and fat. Fat precursor cells then migra...

System Drastically Cuts Down Botulism Detection Time

...ut life. The first step in fat production involves proliferation of mesenchymal stem cells, followed by differentiation into fat cell precursors called preadipocytes. Mesenchymal stem cells can differentiate into various cell types, including bone, cartilage, muscle, nerve, and fat. Fat precursor cells then migra...

Short-term Bio Sensors Monitor From Afar

...ut life. The first step in fat production involves proliferation of mesenchymal stem cells, followed by differentiation into fat cell precursors called preadipocytes. Mesenchymal stem cells can differentiate into various cell types, including bone, cartilage, muscle, nerve, and fat. Fat precursor cells then migra...

Key To Stem Cell Transplant Success Is Tricking Immune System

...ut life. The first step in fat production involves proliferation of mesenchymal stem cells, followed by differentiation into fat cell precursors called preadipocytes. Mesenchymal stem cells can differentiate into various cell types, including bone, cartilage, muscle, nerve, and fat. Fat precursor cells then migra...

Human brain is still evolving

...halin and ASPM code for proteins that regulate the proliferation of brain cells from immature neural stem cells, their function has not yet been determined, said Lahn. ...

Mechanism for Epstein-Barr virus protein's role in blood cancers discovered

...major regulator of several genes in charge of cell proliferation and cell-cycle regulation. In the nucleus, Rb normally binds to E2F, turning off genes involved with cell proliferation. Using human cell cultures infected with the Epstein-Barr virus, the investigators found that EBNA3C recruits a group of molecules...

FSU biologists describe key role of signal-transcribing gene during cell cycle

... pathway as Cut linked them to the control of cell proliferation in the egg chambers, which they observed at different stages. When Cut accurately transcribed the Notch signals, the cells progressed appropriately from the conventional mitosis (replication and division) to the specialized endocycle, where cells ce...

Researchers discover new form of cancer gene regulation

...nated series of genetic control events that create proliferation of cells, signals for further differentiation, pro...then results in cellular differentiation, cellular proliferation or cellular death as pattern formation proceeds. An important signal transduction pathway critica...

Chlamydia parasite lives off our fat

...lets to its protective vacuole but also causes the proliferation of new lipid droplets on the host. The co-option of lipid droplets appears to be essential for Chlamydia pathogenesis. When the researchers used drugs to inhibit lipid droplet formation in the host, they sharply impaired bacterial growth. That findi...

'Computer-chemistry' yields new insight into a puzzle of cell division

... its docking with the kinase, could halt cell over proliferation to treat such cancers. However, developing such drugs has been hampered by lack of detailed understanding of how the Cdc25s fit with their associated kinases. "To me this is the culmination of my six years here at Duke," said Johannes Rudolph, the ...

Texas scientists discover how a hepatitis C protein promotes liver cancer

...king out this 'tumor suppressor' and promoting the proliferation of liver cells, this viral protein is setting up the liver for cancer." According to the federal Centers for Disease Control and Prevention, about 85 percent of liver cancer cases in the United States occur in people infected by the hepatitis C viru...

Scientists directly view immune cells interacting to avert autoimmunity

...utoimmune T cells and dendritic cells that lead to proliferation of autoimmune cells and eventually tissue destruction. Co-authors on the paper and collaborators in the research along with Tang, Krummel and Bluestone are Jason Y. Adams, a medical student at UCSF; Mingying Bi, MS, staff research associate; and Br...

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