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Tag: "proliferate" at biology news

New binding target for oncogenic viral protein

... and Molecular Biology journal. DNA tumor viruses proliferate by hijacking their host cell's DNA replication machinery. In order to do this, they have evolved mechanisms to override normal cellular replication controls. Simian virus 40 (SV40) accomplishes this task by producing the highly oncogenic large T anti...

Scientists discover the cellular roots of graying hair

...a is dangerous for the oppositereason –melanocytes proliferate uncontrollably to form tumors and arehard to kill with treatment.“Preventing the graying of hair is not our goal,?emphasizes David E.Fisher, MD, PhD, director of the Dana-Farber Program in Melanoma, andsenior author of the Science paper. “Our goal is...

Fundamental Finding Yields Insight into Stem Cells, Cancer; Opens Door to Drug Discovery

...a is dangerous for the oppositereason –melanocytes proliferate uncontrollably to form tumors and arehard to kill with treatment.“Preventing the graying of hair is not our goal,?emphasizes David E.Fisher, MD, PhD, director of the Dana-Farber Program in Melanoma, andsenior author of the Science paper. “Our goal is...

Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

...a is dangerous for the oppositereason –melanocytes proliferate uncontrollably to form tumors and arehard to kill with treatment.“Preventing the graying of hair is not our goal,?emphasizes David E.Fisher, MD, PhD, director of the Dana-Farber Program in Melanoma, andsenior author of the Science paper. “Our goal is...

Estrogen-like Component of Plastic Stimulates Growth of Certain Prostate Cancer Cells

...ated receptors for androgens, the malehormone, can proliferate in response to BPA.“The results may have implications for men who develop BPA-susceptiblemutations in their androgen receptor genes during the course ofprostate cancer treatment, although these concepts will need to beverified in animal systems,?acco...

U of T researchers map role of Epstein-Barr virus in cancer

...the cell determines whether cells will continue to proliferate or stop dividing and die. USP7 is a protein that binds to p53 and makes it stable. Under those conditions, cells stop growing and die, which is a natural state of cell regulation. Once EBNA1 is introduced to cells, however, this protein interferes wi...

Random gene expression may drive HIV into hiding

...ell with low levels of the virus and allowed it to proliferate into many genetically identical copies of itself, he found that these progeny did not all show the same behavior: some turned their viral expression on high and others turned it off. This dichotomy in cell fate from genetically identical cells is co...

New tool reveals secrets of migrating cells

...to the very outside edge of the cortex, where they proliferate and fill up the cortex. At this point, Witt said, they undergo the first of two tests to see if their surface receptors (called T cell receptors) work properly. Once they pass that test, they start wandering around in the cortex looking for the seco...

VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease

..., which is a type of pre-leukemia where mast cells proliferate abnormally, that showed improvement with IFNγ treatment," he said. "It is possible that other mast cell-related diseases, such as asthma, may respond to IFNγ treatment." According to Ryan, mast cells are packed with granules containing hi...

Climate model links higher temperatures to prehistoric extinction

..., which is a type of pre-leukemia where mast cells proliferate abnormally, that showed improvement with IFNγ treatment," he said. "It is possible that other mast cell-related diseases, such as asthma, may respond to IFNγ treatment." According to Ryan, mast cells are packed with granules containing hi...

Missing Receptor Molecule Causes Tumor Growth

...ction does not work then the destructive cells can proliferate uncontrollably. Signal Without Effect Prof. Michael Krainer and his team from the Medical University of Vienna have now been able to prove that programmed cell death does not function in cells of certain tumors in the ovaries. Not because the starti...

Nanoparticles carry cancer-killing drugs into tumor cells

...ction does not work then the destructive cells can proliferate uncontrollably. Signal Without Effect Prof. Michael Krainer and his team from the Medical University of Vienna have now been able to prove that programmed cell death does not function in cells of certain tumors in the ovaries. Not because the starti...

Stem Cells Found In Cerebellum; Possible Cell of Origin for Childhood Brain Tumors

... cells. They are known for their unique ability to proliferate extensively and give rise to both new stem cells as well as a host of specialized cells that perform designated tasks in a particular tissue or organ. But when stem cells become activated at the wrong time or place, rapid proliferation can give rise ...

Molecular mechanism of feather formation found

...dge grows in length by recruiting new cells, which proliferate at the growing base of the feather germ, to join the base of that barb ridge," Harris says. "The variations in the initial number of barb ridges will directly affect the shape, and consequent function, of the feather." To test the activator-inhibito...

The making of a fat cell

...ve, and fat. Fat precursor cells then migrate and proliferate at the site of fat production, where they differentiate further to become spherical adipocytes. "The multistep process is regulated by numerous hormones and is accompanied by dramatic changes in cell shape and gene expression," Saltiel said. The te...

System Drastically Cuts Down Botulism Detection Time

...ve, and fat. Fat precursor cells then migrate and proliferate at the site of fat production, where they differentiate further to become spherical adipocytes. "The multistep process is regulated by numerous hormones and is accompanied by dramatic changes in cell shape and gene expression," Saltiel said. The te...

Short-term Bio Sensors Monitor From Afar

...ve, and fat. Fat precursor cells then migrate and proliferate at the site of fat production, where they differentiate further to become spherical adipocytes. "The multistep process is regulated by numerous hormones and is accompanied by dramatic changes in cell shape and gene expression," Saltiel said. The te...

Key To Stem Cell Transplant Success Is Tricking Immune System

...ve, and fat. Fat precursor cells then migrate and proliferate at the site of fat production, where they differentiate further to become spherical adipocytes. "The multistep process is regulated by numerous hormones and is accompanied by dramatic changes in cell shape and gene expression," Saltiel said. The te...

Worms know bad food when they smell it

...ablish an infection inside the worm's gut and they proliferate there. It's exactly like food poisoning," Bargmann explained. If the worm has ingested enough of the bacteria, it can die quickly, but milder cases allow the worm to live for several days ?and head off in search of better food. So, the researchers su...

USC researchers track down the stem cells that create feathers

... base of each individual feather follicle. As they proliferate and differentiate, their progeny is displaced upward to create a feather. When the bird molts, the quill of the feather is dislodged from the follicle with a tapered proximal opening-the very feature that has historically made feathers so useful as w...

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