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Tag: "profiling" at biology news

Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering

...rray-- Dr. Brett Tyler who studied transcriptional profiling ofPhytophthora sojae infection of the soybean plantThe Affymetrix GeneChip Consortia Program is a collaborative initiativethat enables the plant and animal research communities to consolidatetheir sequence data on the Affymetrix industry-standard Gen...

Alcohol's effects on gene expression in the central nervous system

...hat used genetic animal models: # Gene expression profiling in the nucleus accumbens, prefrontal cortex, and v...use strains. "We were able to use gene expression profiling to determine that alcohol produces multiple effects on different biological processes," said McBride...

Agilent Technologies releases automated literature search tool for biology researchers

...re available as plug-ins for network and molecular profiling analyses, new layouts, additional file format support and connection with databases. More information about the Cytoscape platform and project is available on the Web at www.cytoscape.org. ...

Products containing specific probes for detecting alternative splice forms protected

...roduct line launched earlier this year. The genome profiling market is rapidly growing, and SpliceArrays are th...es ExonHit's leadership in the field of expression profiling and positions the company as the only partner for the conception or use of gene profiling microarray...

GeneNotes - A novel information management software for biologists

...information is a challenging task in a genome-wide profiling research project. Most databases and online computational tools require a direct human involvement. Information and computational results are presented in various multimedia formats (e.g., text, image, PDF, word files, etc.), many of which cannot be ...

Doctors closer to using gene analysis to help trauma patients

...sting method ?was not significant, suggesting that profiling gene reactions may provide meaningful information to doctors. The next step is for scientists to continue the experimental procedures in larger multicenter trials, following hundreds of patients over time to describe the molecular profile of healing...

Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

...analytical process for whole blood gene expression profiling can now be accomplished." "The ability of the PAXgene(TM) Blood RNA system to preserve RNA expression levels from the time of sample collection to the time of RNA isolation is a critical component to obtaining accurate gene expression profiles," sai...

Delaware scientists make significant advance in study of small RNAs

...mall RNAs, the scientists used the transcriptional profiling technology called Massively Parallel Signature Sequencing (MPSS), which was developed by Solexa Inc. of Hayward, Calif. Green and Meyers pioneered the application of MPSS to small RNAs in collaboration with scientists at Solexa. Green said that s...

Microarray technology for tailoring breast cancer therapy

...' group. The researchers also used gene expression profiling to separate patients who did well with and without adjuvant therapy, and those whose tumours failed to respond to treatment. An analysis of the genes expressed in the tumours of all 159 patients showed that 64 genes were used to separate the patient...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

...er establish an important role for microarray gene profiling as a predictor of clinical outcome in ovarian cancer, and could eventually provide clinicians with insights into the mechanisms of drug resistance. "In many patients with advanced ovarian cancer, post-operative treatment with first-line chemotherapy...

World first research to speed up cure for ear infections

...issue," Dr Ghassemifar said. "Through DNA or gene profiling of animal models we hope to learn which molecules are active as the ear drum heals and we will then target those to speed up the healing process." Dr Ghassemifar said the clinical research into the wound healing process was a major milestone towards...

Absence of critical protein linked to infertility

...onditions during implantation. After messenger RNA profiling zeroed in on C/EBPb's activity, the researchers collaborated with Peter F. Johnson of the National Cancer Institute's Laboratory of Protein Dynamics and Signaling, who created mice that lacked the protein. The experimental mice were then used to obs...

Newly discovered killer cell fights cancer

... in infection and cancer. Meanwhile, the group is profiling IKDC genes to find a specific marker that could help them identify a human counterpart. ...

A catalogue of proteins

...es." The researchers hope that protein correlation profiling will allow them to determine which proteins participate in failures of regulation. This could contribute to research into diseases which occur when communication between cells is disturbed. ...

Prozac's target revealed

...heir existence, have been a mystery until now. By profiling the telltale marker proteins produced by different kinds of cells in the brains of adult mice, the researchers first defined discrete steps in the complex process, called neurogenesis, that converts unspecialized stem cells into mature, specialized n...

The Midas Bug -- the bacterial alchemy of gold

...ofilm on the surface of gold grains collected. DNA profiling of this biofilm identified 30 bacterial species with populations unique to the gold grains when compared to the surrounding soils. One species was identified on all of the DNA-positive gold grains from both locations. DNA sequence analysis of this ...

Reversing 'hibernating' heart muscle focus of UB researchers

...el that will be translatable to humans. Proteomic profiling will identify candidate mitochondrial proteins in the swine with established viable dysfunctional myocardium that do not have significant cardiac scar tissue. "These protein studies will be coupled with assays of mitochondrial respiration and of the...

Study provides first look at the 'birth' of a retina cell

...h as macular and other retinal degenerations. Gene profiling of rods and cones in disease models at various stages of pathogenesis could help scientists identify molecular targets for drug treatment. Swaroop is hopeful that his research group can use the fluorescent protein to illuminate the chain of events ...

Study offers innovative profile of enzyme that aids tumor growth

... This experimental method of integrated molecular profiling used in the study should also advance the function...lic networks. A primary advantage of metabolite profiling in natural biological systems is that it circumvents some of the most time-consuming steps that acco...

Mayo Clinic: Gene expression profiling not quite perfected in predicting lung cancer prognosis

...significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review...e interest in and the knowledge of gene expression profiling in medical science has exploded since the completion of the human genome project in 2003. Researcher...

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