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Tag: "profile" at biology news

Compounds in plastic packaging act as environmental estrogens altering breast genes

...d that exposure to BPA changes the gene expression profile of mammary tissues as a function of age. That is, there was a significant increase in protein production governed by various genes at increasing ages from 21 to 100 days." These included proteins regulating cell proliferation and differentiation, in...

B-15A collides with Antarctic ice tongue

...microarrays to perform thousands of experiments to profile chemical effects on biological systems, thereby creating a vast resource of gene expression responses to chemical toxicants. The data will eventually be made available through the NIEHS National Center of Toxicogenomics' Chemical Effects on Biologica...

Virus-host interactions at sea effect global photosynthesis

...microarrays to perform thousands of experiments to profile chemical effects on biological systems, thereby creating a vast resource of gene expression responses to chemical toxicants. The data will eventually be made available through the NIEHS National Center of Toxicogenomics' Chemical Effects on Biologica...

Agilent Technologies releases probe sequence, annotation information for all its commercial gene expression microarrays

...microarrays to perform thousands of experiments to profile chemical effects on biological systems, thereby creating a vast resource of gene expression responses to chemical toxicants. The data will eventually be made available through the NIEHS National Center of Toxicogenomics' Chemical Effects on Biologica...

FDA Works To Speed The Advent Of New, More Effective Personalized Medicines

...e providers to identify sources of an individual's profile of drug response and predict the best possible tre... eventually be able to analyze a patient's genetic profile and prescribe the best available drug therapy and dose from the start. Both the guidance and a new W...

Study reveals new technique for fingerprinting environmental samples

...omic Tags, or EGTs, these indicators capture a DNA profile of a particular niche and reflect the presence and...living there." The EGT fingerprints capture a DNA profile of a particular niche and reflect the presence and levels of nutrients, and pollutants, as well as f...

Canada approves marijuana-based pain spray

...e of high quality and possess an acceptable safety profile based on a benefit/risk assessment for the approved use. “Effective pain control and management are extremely important in a disease like MS,?said Dr. Allan Gordon, Neurologist and Director of the Wasser Pain Management Centre, Mount Sinai Hospital,...

Medical whistleblowers speak out

...top that and didn't." Graham was one of five high profile medical whistleblowers invited by the medical investigative journalist Jeanne Lenzer to meet together in Washington DC on May 15th 2005 to share their accounts of practices in medicine and medical research that they believe are risking the public's h...

FDA Announces Series of Changes to the Class of Marketed Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

...the market because the overall risk versus benefit profile for the drug is unfavorable. FDA has also asked Pfizer to include a boxed warning in the Celebrex (celecoxib) label. Pfizer has agreed to suspend sales and marketing of Bextra in the U.S., pending further discussions with the agency. Pfizer has agree...

miRNA profiling

...chl and colleagues describe the most comprehensive profile to date of microRNA (miRNA) expression during zebrafish development. The authors cloned 154 distinct miRNAs (10 of which are completely novel) in a developmental and tissue-specific manner. They also identified ?for the first time ever in a vertebra...

New Drugs For Bad Bugs: UF Approach Could Bolster Antibiotic Arsenal

...ions of an antibiotic, mimicking the concentration profile present in a patient at the actual site of an infection. They then measure how quickly the bacteria are killed or see if they regrow, and use mathematical modeling to estimate the optimal dose. “Based on the results in the lab, then you can do a cli...

Gene Signatures Predict Interferon Response For Multiple Sclerosis Patients

...on therapy produces changes in the gene expression profile of targeted cells—that is, it inhibits or activates certain genes—which in turn alters the cells' activity. Blood samples were taken from 52 patients with relapsing-remitting MS (marked by acute flare-ups followed by partial or full recovery), and t...

Asthma gene clusters identified

...o suffer from acute asthma attacks share a genetic profile that appears to be unique to these children, accor...aving an acute asthma attack had a gene expression profile that was clearly different from those seen in someone with stable (controlled) asthma. The amazing t...

FDA Approves New Drug to Treat Type I and Type II Diabetes

...r off-label use in patients where the benefit/risk profile has not been characterized or demonstrated is also a concern and will be monitored by the sponsor. The Medication Guide informs patients that Symlin should only be used if they are already using their insulin as prescribed, but still need better blo...

New research indicates a 'troubled' greenhouse is brewing

...e amount of rainfall because the spread within the profile of carbonate nodules is related to the difference in precipitation between the driest and wettest month. Retallack uses this feature in ancient soils to reinterpret past climates. Retallack is an authority on paleosols (ancient soils) and is writing...

Ice core 'dipstick' indicates West Antarctic ice has thinned less than believed

... more than 600 miles. An ice sheet with such a low profile and gradual decline would have had to have a very slippery bed to maintain its continuous flow, Waddington said, and it appears the ice flowed vigorously despite being relatively thin. One major implication of the research, he said, is that it dispu...

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