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Tag: "profile" at biology news

Hooked on fishing, and we're heading for the bottom, says scientist

...ono or Mandela to give finned creatures the public profile of cute and furry ones. "It's time for leadership on global fisheries issues. It's time to act," says Dr. Pauly, Director of the Fisheries Centre at the University of British Columbia in Vancouver, Canada. "We don't need more science. This is a mess...

Environmental metagenomics diagnosing extreme environments, tapping opportunities for clean energy

...tal Genomic Tags or EGTs, that provide a metabolic profile of any environment, even such extreme conditions as acid mine drainage," says Edward M. Rubin, DOE JGI Director. "We can then survey this vast catalog of biodiversity and harness the microbial pathways that catalyze the conversion of lignocellulosic...

Serious adverse reactions to smallpox vaccine appear to be limited

...tlanta, and colleagues examined the vaccine safety profile among civilians who received smallpox vaccine between January 24 and October 31, 2003. The researchers evaluated adverse events reported via the Vaccine Adverse Event Reporting System (VAERS) and the Centers for Disease Control and Prevention. A t...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

A newly identified gene expression profile could help predict how patients with advanced ovar...stra's group has been working to develop a genetic profile of ovarian cancer that will enable clinicians to more accurately determine a patient's prognosis. As...

Researchers discover new form of cancer gene regulation

... nucleus of the cell. The altered gene expression profile then results in cellular differentiation, cellular proliferation or cellular death as pattern formation proceeds. An important signal transduction pathway critical to early development of humans and animals involves the genes Sonic hedgehog (the s...

UK sperm donor crisis

...we saw a sharp fall in numbers and a change in the profile of the applicants, perhaps reflecting the attitudes of different groups to anonymity. There was a significant increase in the number of men who had partners and, after the Department of Health announcement that anonymity would be removed, there was a...

Scientists characterize proteome of human cornea

...of corneal diseases. Identification of the protein profile of the normal human cornea may also be very useful in the effort toward generating artificial corneas for transplantation." To follow up on their initial research, Dr. Enghild and his colleagues have begun proteomic studies of corneas affected by gr...

Eleven gene 'signature' reliably predicts cancer prognosis

... consistently displays a stem cell-like expression profile in metastatic tumors in a mouse cancer model as we... The results show that a stem cell-like expression profile of the 11-gene signature in primary tumors is a very consistent and powerful predictor of a short in...

New gene scanning technology marks a major advance in disease research

...uture it could lead to a very personalised genetic profile of a whole range of genes relevant to lifestyle, health and drug prescribing, leading to more personalised medicine and screening.' Professor Day's group is using combinations of meltMADGE and a second technology called endo VII MADGE to explore var...

Results of world's first gene therapy trial for arthritis show approach safe, feasible

...eported in PNAS. AAV appears to have a good safety profile and, in animals, facilitates more extended gene expression. The investigators hope to conduct additional clinical trials in both osteoarthritis and rheumatoid arthritis using AAV to transport the gene. In addition to Drs. Evans and Robbins, other au...

Scientists uncover new clues about brain function in human behavior

...e amygdala response perfectly reflected the unique profile of social and non-social anxiety in Williams Syndrome," said Meyer-Lindenberg. "Because our data showed that the amygdala did still function, although abnormally, in Williams Syndrome, we wondered whether it might be its regulation by other brain reg...

Rensselaer researchers develop approach that predicts protein separation behavior

...mental results by predicting the actual separation profile of proteins in chromatographic columns. Chromatography techniques are used to identify and purify molecules, in this case, particular proteins. "We intend to test the model against more complicated protein structures as part of its further developme...

Most common lung cancers may begin in newly discovered cells

...ng tumor, Jacks said. The similar genetic activity profile of mouse tumors with K-ras mutations to the profile of human lung cancer samples make the researchers optimistic about the relevance of targeting BASCs ...

Researchers seek to discover what really happens when a virus enters the body

...? Bell and Duca's collaboration is an attempt to profile the host-virus system using the electrical enginee... quantitative method that derives a characteristic profile or fingerprint from the IIS of any host-virus system. If their method can achieve results in hours i...

The first impact factor for PLoS Biology ?13.9

... provide biologists who support open access a high profile journal for their best research papers and to demonstrate that open-access publishing works for a selective journal that only publishes outstanding science. Thanks to support from funding agencies, librarians, open-access advocates, and the scientifi...

Tamoxifen-like drug suggests new ways to selectively block estrogen

... he said, "very close to the day where a proteomic profile of a tumor will determine the best SERM or SERD or other endocrine therapy that will yield maximal benefit in the clinic." New tools such as the Advanced Photon Source at Argonne National Laboratories are making this sort of once-grandiose plan more...

Gov't Creates Gene Database of Normal Human Tissues

...rom another." Each organ revealed a very distinct profile of active genes, different from all others. However, the gene profiles from different organs that share similar biological functions also showed patterns of expression. For example, though the cerebrum and the cerebellum are two distinct parts of the...

Affymetrix Launches New Globin-Reduction Kits and Protocol Developed with PreAnalytiX

...ix GeneChip technology and improve gene expression profile results of cellular RNA extracted from whole blood. The combination of the GeneChip Blood RNA Concentration Kit (featuring the PAXgene Blood RNA System) and the GeneChip Globin-Reduction RNA Controls standardizes all the steps of whole blood RNA pro...

Putting ecology back into river restoration

... Ecology, which this month is publishing a special profile on river restoration. Opening the debate is a paper by 22 leading US river ecologists proposing five criteria for ecologically successful river restoration. Their aim is to arrive at an agreed set of standards which would eventually be endorsed by th...

Doctors closer to using gene analysis to help trauma patients

...ds of patients over time to describe the molecular profile of healing in response to burns and traumatic injury, researchers say. ...

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