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Staphylococcus aureus hides out in cells

...red the lung cells, the bacteria’s gene expression profile dramatically changed: gene expression for bacterial metabolic functions and transport shut down, putting the bacteria in a dormant state. Simultaneously, production of toxins potentially lethal for the epithelial cells becomes strictly controlled to ...

Gene expression patterns predict rapid decline in idiopathic pulmonary fibrosis patients

... ONE, a subset of patients with a specific genetic profile has a much more rapid progression to complete pulmonary failure and death without a lung transplant. Based on observations in the clinic that some IPF patients display a more rapidly progressing disease course, researchers at the Simmons Center for ...

How to steer a moving cell

.... Their work, providing the first comprehensive profile of cell movement, could lead to a better understan...ns regulate cell movement." The research team’s profile of chemotactic cells is the first and most comprehensive catalog of proteins that exists to date, ac...

Dinosaur hearing, listening to muscle noise, quieter cubicles

...had assumed that the main important factor was the profile of a wind instrument's bore, the chamber where air vibrates and produces pitch. Wilfried Kausel of the University of Music and Performing Arts in Austria ( kausel@mdw.ac.at ) will present growing experimental evidence that wall vibrations and thic...

Brain's reward circuit activity ebbs and flows with a woman's hormonal cycle

... that period. Men showed a different activation profile than women during both anticipation and delivery of rewards. For example, men had more activity in a striatum (signal relay station) area during anticipation compared to women and women had more activity in a frontal cortex (executive hub) area at th...

Gut research yields new anti-cancer approach

...ercome the limits of current treatment because the profile of molecules likely to be pumped out by drug efflux proteins is known, and at least one of the PPARgamma inhibitors does not match it. In addition, PPARgamma inhibitors do not bind to the standard tubulin-binding site that renders Taxol useless when ...

New player in commitment to life as a fat cell

...R was at the top of the list of genes that fit the profile of a fat generator. Indeed, they found evidence that XOR controls PPAR-gamma a transcription factor considered to be the master regulator of fat production since it is both necessary and sufficient for adipose differentiation both in vitro and in ...

Elucidation of the genome for diabetics with DNA chips

...evere obesity, we need to be able to establish the profile of the young adults most at risk; this would allow personalised preventive strategies to be implemented. Some of the genes identified in this study, including the ZnT8 zinc transporter gene in particular, may be good targets for treatments to combat ...

New study may show how to forestall a fatal, virus-caused immune-system meltdown

...elieve they’ve found a way to spot the biochemical profile of an inappropriate immune response to viral infection ?an important step toward developing new therapies that may head off or stop an otherwise fatal immune system meltdown. In a paper published in the February 14 issue of the Journal of Virolog...

OHSU lab finds meth receptor that could lead to therapy

... name a few. "With this kind of pharmacological profile and brain distribution, we hypothesized TAAR1 could mediate some of meth’s metabolic and behavioral effects," explained Grandy, who also directed the groundbreaking research. "In our most recent article, we provide clear evidence that methampheta...

Procedure predicts embryos most likely to result in pregnancy

...ccessful embryos, the team established a metabolic profile of embryos that resulted in pregnancies as well as...form of spectroscopy, will determine the metabolic profile of the embryo and accurately predict its reproductive potential," said Seli, who plans to confirm th...

Computer imaging assists with facial reconstructive surgery

...ons who use computer imaging software, analysis of profile photographs is the most valuable tool. Even when ...stablished soft tissue measurements as a guide for profile facial analysis.?...

Health Canada approves cold and flu medicine

..." The NHPD’s safety review confirmed the safety profile of COLD-fX with no known side effects or drug interactions for generally healthy individuals. Health Canada established new regulations effective Jan. 1, 2004, to monitor and manage the NHP industry. CV Technologies was the first company in Canada...

Stretching DNA to the limit

... DNA strands. Upon exposure to UV light, the force profile of the viral DNA changes dramatically in a dose-de...light. They conclude that the changes in the force profile of viral DNA exposed to UV light are due to the local unwinding of the double helix in some regions ...

A healthier start to a pig's life

...ing contacts in other countries and in raising the profile of the project....

Ladybugs may be cute, but watch out when they get near wine

...rliest direct ancestor as having a vertical facial profile and a relatively large brain ?an interpretation widely accepted until now. Dr. Bromage"s reconstruction also suggests that humans developed a larger brain and more vertical face with a less pronounced jaw and smaller teeth at least 300,000 years...

Man's earliest direct ancestors looked more apelike than previously believed

...rliest direct ancestor as having a vertical facial profile and a relatively large brain ?an interpretation widely accepted until now. Dr. Bromage"s reconstruction also suggests that humans developed a larger brain and more vertical face with a less pronounced jaw and smaller teeth at least 300,000 years...

Protein therapy may reduce infarct size in heart attack patients

...ssociated with a favorable safety and tolerability profile and based on this ‘first in human?trial, we are interested in pursing larger studies to determine the therapeutic value of this treatment for heart attack patients receiving reperfusion therapy." ...

Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients

...ris Therapeutics. "We were confident in the safety profile given our previous experience using the intravenous form of these stem cells to treat other diseases in later stage clinical trials. However, we did not expect to see the across-the-board clinical improvement observed in patients at this early stage...

Drug treatment improves learning in mice with Down syndrome symptoms, Stanford/Packard study shows

...e drug was withdrawn. In fact, the drug’s activity profile mirrored that of some well-known psychiatric medications. "This suggests that it’s not just the removal of the excess inhibition that allows learning to occur, but that we’re instead strengthening synapses through some type of long-lasting neurona...

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(Date:4/17/2014)... April 17 In the most densely forested and ... reflect two centuries of human needs, values and practices. ... clearing forests for agriculture and development, have set the ... U.S. Forest Service study reports. , The report ... and management needs in the Northern United States ...
(Date:4/17/2014)... development of stem cell therapies to cure a variety ... cell populations based on cell surface markers. Researchers from ... that is highly expressed in a type of stem ... describe in an article in BioResearch Open Access ... publishers. The article is available free on the ...
(Date:4/17/2014)... ALBUQUERQUE, N.M. A credit-card-sized anthrax detection cartridge developed ... small business makes testing safer, easier, faster and cheaper. ... causes anthrax, is commonly found in soils all over ... illness in both humans and animals. The bacteria can ... to B. anthracis may occur through skin ...
Breaking Biology News(10 mins):Five anthropogenic factors that will radically alter northern forests in 50 years 2Five anthropogenic factors that will radically alter northern forests in 50 years 3Pocket-sized anthrax detector aids global agriculture 2Pocket-sized anthrax detector aids global agriculture 3
(Date:4/18/2014)... published online in The Gerontologist ... is associated with a decrease in anxiety about death ... control over their lives. In particular, listening to gospel ... death and an increase in sense of control. , ... and men, and individuals of both low- and high-socioeconomic ...
(Date:4/18/2014)... (Seattle, WA April 18, 2014) Benaroya Research ... to research how blocking a particular molecule in metastatic ... and the number of lung metastases. BRI scientists have ... protein can shrink tumors by 60 - 80 percent ... to the lung. The $1.8 million five-year grant comes ...
(Date:4/18/2014)... scientists could lead to potential new treatments for breaking ... , Fibrosis, or scarring, is a hallmark of ... lungs can lead to serious organ damage and, in ... options centers on findings made by Swati Bhattacharyya, PhD, ... that a specific protein plays in promoting fibrosis. ...
(Date:4/17/2014)... pain relief targets that could be used to ... King,s College London made the discovery when researching ... of the body. , Dr Marzia Malcangio said: ... pain generation and our findings could help chemotherapy ... One potential side effect of some chemotherapy drugs ...
(Date:4/17/2014)... the University of California, San Diego School of Medicine ... have suffered a recent major loss are more likely ... , The study is published in this month,s issue ... , Because compassionate behaviors are associated with better health ... insights into ways to improve the outcomes of individuals ...
Breaking Medicine News(10 mins):Health News:Religious music brings benefit to seniors' mental health 2Health News:Benaroya Research Institute evaluates immunology approach to blocking breast cancer 2Health News:New clues on tissue scarring in scleroderma 2Health News:New pain relief targets discovered 2Health News:The ilk of human kindness 2
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