The first tree genome is published: Poplar holds promise as renewable bioenergy resource
...tunities to improve carbon removal from the air by producing trees that effectively shuttle and store more carb...ort to discover new biotechnology-based methods of producing fuels from plant matter (biomass) cost-effectively. Earlier this year DOE published a study summ...Abnormal overexpression of p53 is a predictive molecular biomarker
...tion or that the p53 gene is mutated, incapable of producing effective protein. Tumors that are p53 negative likely have a working p53 gene and protein pathway, as normal p53 levels in cells are typically low. Advexin is farthest along in federal Food and Drug Administration (FDA) review of any experimenta...Does natural selection drive the evolution of cancer?
...ighboring cells that aren't investing resources in producing the signals take advantage of the nutrients nonetheless. Mutualism describes a situation in which two organisms interact in a mutually beneficial way. Tumor cells send signals to stimulate the growth of the cells that form the scaffold in which th...Pair of microRNA molecules controls major oncogene in most common leukemia
...block transcription of genes by stopping them from producing messenger RNA or can inhibit translation of the genes by blocking production of proteins from messenger RNA, according to Pekarsky. Earlier this year the investigators provided the first direct evidence that over-expression of an miRNA molecule coul...Advance helps explain stem cell behavior
...esearch identified the subset of genes involved in producing the various types of spinal cord cells ?there may be 10s to 100s of cell types just in the spinal cord. The cell types are created very quickly in early embryonic development by a pattern formation mechanism, and then mature more slowly as the centra...Professors to develop hand-held pathogen testing device
...ot dangerous to humans by themselves. But the gene producing the cholera toxin is harmful. These genes serve as good markers for detection. Hashsham's device will be designed to look for such marker genes. "This technology is rugged and highly parallel; it can analyze lots of marker genes in a lot of sample...Reading Shakespeare has dramatic effect on human brain
...rs also found that when participants read the word producing the functional shift there was no N400 effect indicating that the meaning was accepted but a P600 effect was observed which indicates a positive re-evaluation of the word. The team is now using magnetoencephalography (MEG) and functional magnetic re...Three-dimensional, miniature endoscope opens new diagnostic possibilities
...r bundles may be more flexible but have difficulty producing high-quality images. The new device developed at MGH-Wellman uses a technology called spectrally encoded endoscopy (SEE). Multicolored light from a single optical fiber ?introduced through a probe about the size of a human hair ?is broken into its...New target for cancer therapy identified
...oteins that are involved in stopping the gene from producing a protein called telomerase that is essential if cancer cells are to proliferate. Telomerase plays a key role in controlling the life span of cells by modifying structures called telomeres that are found at the end of chromosomes. Although it is in...Insulin receptor stops progression of Alzheimer's disease
...(STZ), a compound that is known to destroy insulin producing cells in the pancreas and cause diabetes. When inj...ed different regions of the brain, with PPAR delta producing the most striking effect in preserving the hypothalamus and temporal lobes, areas of the brain respo...Different strategies underlie the ecology of microbial invasions
...ng susceptible competitors, which become factories producing more parasites. Amplification therefore makes phage carriers able to successfully compete with phage-susceptible bacteria even faster when the carriers are rare, whereas chemical killers can only win in a well-mixed environment when chemical carriers...Molecular 'on/off switch' controls immune defenses against viruses
... that the virus launches a counterattack on RIG-I, producing a protein called a protease to disrupt the signaling process, preventing interferon production and allowing viral replication. Just how RIG-I signaling is normally regulated, however, hadn't been known. In the current study, UT Southwestern re...Researchers add to understanding of how brain cells communicate
...xplain how evolution accomplished a critical goal: producing receptor proteins with finely tuned properties that help optimize brain function," said Johnson. NR1/2D receptors may be the least-studied of the major NMDA receptor subtypes, but there is increasing evidence that they play important roles in the ......py. But what if the body could be induced to begin producing these proteins, say by transplanting healthy tissue with the abilities that are lacking? Prof. Yair Reisner and Ph.D. student Anna Aronovich of the Weizmann Institute's Immunology Department, together with colleagues, showed, in research recently pu...New finding points way to foiling anthrax's tricks
...tegy in anthrax, Bacillus anthracis, suggests that producing more than one siderophore is a general strategy of...ar to petrobactin. The researchers suggest that producing a second, stealth siderophore - petrobactin or aerobactin - that has a different molecular structure...Solved: The mystery of flesh-eating bacteria's relentless attack
... other," said Hanski. "Since the bacteria were not producing the peptide, we decided to synthesize it ourselves and give it to mice infected with M14." The mice receiving this peptide survived at a much higher rate than mice that did not receive it. The team also observed many white blood cells at the infec...Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation
...ol levels and arterial plaque and are incapable of producing their own apo A-I. "Any apo A-I that these mice have will come from our gene transfer, making the experimental design very clean," Shah noted. The genes were transferred to the female mice during a bone marrow transplant from male mice. Because m...Why we could all do with a siesta
...cose ?the sugar in food ?can stop brain cells from producing signals that keep us awake. Dr Burdakov's research has shown exactly how glucose blocks or 'inhibits' neurons that make orexins ?tiny proteins that are vital for normal regulation of our state of consciousness. "These cells are critical for respond...Gene therapy prevents the onset of diabetic symptoms in mice
... become stressed and have a harder time growing or producing seeds and seedlings. "Because of the detailed measurements for the last 50 years, we know almost exactly how much calcium was removed by acid rain," said Fahey. "Our treatment was designed to replace just that amount of calcium to bring the system t...... become stressed and have a harder time growing or producing seeds and seedlings. "Because of the detailed measurements for the last 50 years, we know almost exactly how much calcium was removed by acid rain," said Fahey. "Our treatment was designed to replace just that amount of calcium to bring the system t...