Researchers use 'trickery' to create immune response against melanoma
... bladder and surrounding the urethra. The prostate produces the seminal fluid in which sperm is transported. Prostate cancer begins with small changes in size and shape of the prostate gland cells which can develop into an uncontrolled growth of cells. Prostate cancer predominantly affects Western populatio...Targeted drug delivery achieved with nanoparticle-aptamer bioconjugates
... bladder and surrounding the urethra. The prostate produces the seminal fluid in which sperm is transported. Prostate cancer begins with small changes in size and shape of the prostate gland cells which can develop into an uncontrolled growth of cells. Prostate cancer predominantly affects Western populatio...Travelers can avoid jet lag by resetting their body clocks
... and the combination of bright light and melatonin produces a larger phase advance than bright light alone," said Senior Author Charmane Eastman, Ph.D., Director of the Biological Rhythms Research Lab and Professor of the Behavioral Sciences Department at Rush University Medical Center in Chicago. Phase adva...Technique offers new view of dynamic biological landscape
... interact epistatically, such that inhibiting both produces a much greater effect than the sum of the two," he said. ......ied to a microscope slide, the microarray computer produces about 50,000 coloured spots showing which genes are expressed or switched on in the sample. "What we're trying to find out is, what's different in the superior frontal cortex [front of brain] when you compare alcoholics with controls, that's not di...Sea slug mixes chemical defense before firing at predators
...-lysine and L-arginine in the opaline gland, which produces the sticky white component of the secretion, and escapin in the ink gland, which produces the purple dye in the secretion. "Aplysia packages these innocuous precursors separately and then r...Greasing interferon's gears may pave way to greater therapeutic benefits, fewer side effects
...asoned that if we could enhance the way interferon produces its beneficial defensive effects, the body could respond to its normal level of interferon and receive enhanced benefit without side effects," Holtzman says. The group engineered a mutant Stat1 protein in which the identities of two amino acids wer...Key brain regulatory gene shows evolution in humans
...tly. "Also importantly, the part of the gene that produces the prodynorphin protein shows no variation within humans, or even between humans and any of the great apes," said Wray, who is a professor of biology. "So, if we found any variation in this gene due to evolution, it was likely to be in its regulatio...Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method
...d technology. In conventional clinical settings it produces images of the body by detecting radiation emitted from radioactive substances, such as fluorodeoxyglucose, injected into the body. In the work reported by Witte's group, PET was used to follow immune cells whose DNA included "reporter genes," genes e...PET imaging reveals the immune system at work
...d technology. In conventional clinical settings it produces images of the body by detecting radiation emitted from radioactive substances, such as fluorodeoxyglucose, injected into the body. In the work reported by Witte's group, PET was used to follow immune cells whose DNA included "reporter genes," genes e...Team led by Carnegie Mellon University scientist finds first evidence of a living memory trace
...ural Computation. "Our findings show that an odor produces a memory trace of synchronized neural activity that lasts several minutes after a bee initially senses it," said Galán. "This is the first time anyone has revealed a short-term, stimulus-specific neural pulse within the living brain that occurs after...Novel protein complex enables survival in hostile environment
...thanogenesis is a microbial process in nature that produces methane, an energy resource and a green house gas.... one living cell, because the reduction of sulfate produces sulfite as an intermediate, which damages an essential component of the methane production machinery...Blocking the nerve receptor EP1 in mouse models reduces brain damage caused by stroke
...an increase in the production of COX-2, which then produces PGE2. "A lot of the previous findings kept bringing us back to PGE2 and its receptors," Doré said. "So we investigated whether it's possible to block the EP1 receptor so PGE2 couldn't trigger toxic effects." Doré's team first injected either the ...'Acid rain' and forest mass: Another perspective
...ed that the atmospheric deposition of contaminants produces damage in the forest masses of Bizkaia and may be aggravated in the future. ...Chemical compound inhibits tumor growth, size in new mouse study
...erson explains that the Maillard reaction not only produces desirable changes, such as a golden brown color an...erson explains that the Maillard reaction not only produces desirable changes, such as a golden brown color and toasty aroma, but also can sometimes cause off-f...Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, Stanford study finds
...hy. The dystrophin gene is mutated and as a result produces a defective protein in the roughly 20,000 people in the United States with the most common form of the disease. Using gene therapy to treat muscular dystrophy isn't a new idea. Thomas Rando, MD, PhD, associate professor of neurology and neurological...Toasty oat aroma influenced by presence of health-linked polyphenols
...erson explains that the Maillard reaction not only produces desirable changes, such as a golden brown color an...erson explains that the Maillard reaction not only produces desirable changes, such as a golden brown color and toasty aroma, but also can sometimes cause off-f...Molecular cabal contributes to stroke damage
...rugs to protect against the molecular "cabal" that produces such lethality. In their experiments, the researchers discovered the molecular mechanism linking two key components of neuronal damage due to oxygen starvation, or ischemia. One component is a type of receptor called an NMDA receptor (NMDAR). This r...Researchers identify molecular anchor that allows bacterial invasion of central nervous system
..., and their colleagues have identified a gene that produces a fat-sugar complex, which in turn anchors a molecule called LTA (short for lipoteichoic acid), found on the bacterial cell wall. This anchoring is a necessary first step for bacteria to cross from the bloodstream into the central nervous system thro...Sudden change in social status triggers genetic response in male fish, study finds
...ticularly interested in a gene called egr-1, which produces a regulatory protein that activates other genes. The research team hypothesized that, when a male encounters an opportunity to climb the social ladder, the egr-1genes in his brain send an immediate signal to the gonadotropin-releasing hormones cells ...