New treatment for severe malaria
...essels is that once in the blood cell the parasite produces proteins that project from the surface of the cell and bind with receptors on other blood cells and on the vessel wall, and thus act like a glue. The challenge facing scientists has been to break these bonds so that the infected blood cells can be tr...Free radical cell death switch identified
...hey create oxidative stress. As the body ages, it produces more and more free radicals and its own antioxidants are unable to fight this process, which results in the generation of highly reactive oxygen molecules that inflict cellular damage by reacting with biomolecules including DNA, proteins, and lipids....Fire ants: Their true story told by the scientist who loves them
...olonies, unusual variability known as polymorphism produces big-headed workers 20 times heavier than their smallest counterparts. Between chapters science-rich enough for biologists but accessible to educated readers, "The Fire Ants" has "Interludes" ?wry asides on the pleasures and pitfalls as scientists me...'Smart' genetic therapy helps the body to heal itself
...all carry a copy gene (SMN2). However, this only produces about 10% of the correct protein; insufficient to prevent the diseases. The severity of the SMA is influenced by the number of SMN2 genes, which normally vary between one and four ?the more copies there are the better the patient does. Professor W...Interfering RNA silences genes in 'slippery' immune cells
...A. The DNA holds a sequence of genetic code that produces a specific siRNA after it enters a nucleus. The researchers encased the DNA within an siRNA expression cassette (SEC), an inexpensive, quickly synthesized product that carries genetic sequences to regulate the gene activity that yields an siRNA. Afte...What controls stickiness of 'smart' chromosomal glue
...eiosis ?the specialized cell division process that produces sperm and eggs ?enabling them to separate properly. The researchers, led by Howard Hughes Medical Institute investigator Angelika Amon, published their findings online May 3, 2006, in the journal Nature. Amon and her colleagues are at the Massachus...Just like us, social stress prompts hamsters to overeat, gain weight
...s referred to as corticotrophin releasing hormone, produces the body's "fight or flight" response under stress and helps kick off a cascade of physiological responses. "There are a whole suite of physiological responses that occur as a result of stress," Bartness said. It will take time to unravel all these...Researchers to develop ultra-miniature implantable sensors to measure blood flow
...ysiological monitoring. Transonic Systems already produces miniature devices for measuring blood flow in physiology and pharmacology studies. According to Transonic project engineer Bruce McKee, "Dr. Kan's technology could create even smaller patient monitoring sensors that simultaneously measure blood press...Methane-belching bugs inspire a new theory of the origin of life on Earth
...ar species (one "Methanosarcina acetivorans") also produces acetate--better known as vinegar. Ferry and House, in collaboration with Barry Karger at Northeastern University, showed how carbon monoxide is converted to acetate in a biochemical pathway that includes a well-known pair of enzymes, called Pta ("pho......virus that causes cold sores and ocular keratitis, produces an miRNA molecule. This miRNA is encoded by the Latency-Associated Transcript gene (LAT) in the viral genome and works through a process called RNA interference to prevent normal cell death or apoptosis. Thus, the latent viral infection is maintained...Science captures the essence of fruit
...fruits and flowers. "Extraction is expensive and produces only limited quantities of product, reducing the number of commercially viable options for the extract," says Dr Newcomb. Biofermentation however can produce large amounts of a desired compound at a low cost and with little environmental impact. An...Ten years later, Dolly is still making headlines
... Dr. Burt Adelman of Biogen Idec, the company that produces the recently re-approved multiple sclerosis drug, Tysabri. The Plenary Session is Monday, June 19 from 8:30 a.m. to 11:30 a.m. at the Hynes Convention Center. Biogenerics ?The next revolution in health care? Generic biopharmaceutical drugs, or b...Sleep deprivation doubles risks of obesity in both children and adults
...ges caused by the sleep deprivation. Lack of sleep produces Ghrelin which, among other effects, stimulates appetite and creates less leptin which, among other effects, suppresses appetite. However he says more research is needed to understand the mechanisms by which short sleep is linked to chronic conditions...New light microscope sharpens scientists' focus
...an readily be used with electron microscopy, which produces a detailed image of very small structures ?but not proteins ?in cells," she said. "By correlating a PALM image showing protein distribution with an electron microscope image showing cell structure of the same sample, it becomes possible to understand...Study reveals how cells destroy faulty proteins in cystic fibrosis
...is a fatal disease caused by a defective gene that produces a misshapen form of the protein cystic fibrosis transmembrane conductance regulator (CFTR). People with cystic fibrosis do not have enough CFTR for their cells to work normally because their bodies quickly destroy the mutant protein. "Most cases ...Case Western Reserve University researchers find protein associated with brain cell death
... immune cells triggers a cascade of reactions that produces unregulated free radical production that eventuall...icroglia, the brain's primary immune cell, when it produces an inflammatory response when coming into contact with beta-amyloid fibrils that form the harmful br...When the going gets tough, slime molds start synthesizing
...ersity of natural chemicals and the machinery that produces them gives us a window to look back in time and understand how organisms evolve at the molecular level." ...Friendly bacteria in chewing gum that bites back
...S. Mutans sticks to the surface of teeth, where it produces an aggressive acid that breaks down the enamel. The friendly bugs in the gum will make the S. Mutans clump together, preventing them from becoming attached to the tooth surface. Tests reveal that the chewing gum can reduce the amount of bacteria in t...DOE JGI finishes 100th microbial genome
...ifornia, Davis. Fixes carbon dioxide and nitrogen; produces hydrogen; survives acidic, anaerobic, and low-temperature conditions. Bioremediation Burkholderia species. Jim Tiedje, Michigan State University. Outstanding degrader of polychlorinated biphenyls (PCBs). Chromohalobacter salexigens DSM 3043. (...Sandia work launched on space shuttle shows live cells influence growth of nanostructures
... Ordinarily, the drying of lipid-silica solutions produces an ordered porous nanostructure by a process known as molecular self-assembly. This can be visualized as a kind of tract housing. In the current experiments, however, the construction process is altered by the live yeast or bacteria. During dryin...