Discovery of key protein's shape could lead to improved bacterial pneumonia vaccine
...e discovery of the structure of CbpA was atwo-step process that included studies of how this protein works,followed by determination of its actual structure using powerfullaboratory tools. Previous work by another team suggested that CbpAbinds to pIgR. However, that finding was made in “test-tube?experiments...Critical role in programmed cell death identified
..., opening new avenues for studying and targeting a process vital to development and implicated in cancer and ...entation is required for cells to die and that the process that commits cells to the point of no return happens quickly. Conradt said it's the clearest confirm...New comparative toxicogenomics database
...e discovery of the structure of CbpA was atwo-step process that included studies of how this protein works,followed by determination of its actual structure using powerfullaboratory tools. Previous work by another team suggested that CbpAbinds to pIgR. However, that finding was made in “test-tube?experiments...Scientists develop new color-coded test for protein folding
...oated with cytochrome c began clumping together--a process that caused the solution to quickly change from red to blue as the acidity increased. The researchers were surprised to discover that, when the pH was raised from 4 to 10, the blue solution turned reddish once again--a strong indication that some cy...Probing The Promise And Perils Of Nanoparticles
...nd similar nanoparticles get into cells involves a process called polycation-mediated endocytosis. But Hong's experiments suggest that nanoscale hole formation may be at least as important in allowing materials to travel through membranes. The work that Banaszak Holl, Hong and Leroueil will discuss is one o...Researchers find missing genes of ancient organism
...t are cut out of whole gene transcripts during the process of tRNA maturation. The known tRNA introns in orga...tRNA introns might be remnants of an old essential process of tRNA biosynthesis. "These results may point to extremophiles in the kingdom of Archaea as predec...Scientists identify genetic pathways essential to RNA interference
...(MGH) has identified 80 new genes essential to the process of RNA interference (RNAi), a powerful new researc...ing genes in plants or animals. They used the RNAi process itself to find new genes that participate in the gene-silencing mechanism, which someday may help to...Alcohol's effects on gene expression in the central nervous system
...lude genes involved in the intracellular signaling process (which can alter how the neuron functions), neuropeptide signaling (which modulates nerve cell activity), and myelin structure (which is needed for communication between nerve cells)," said McBride. "Gene expression profiling has also been used to id...Jumping gene helps explain immune system's abilities
...entists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability...changes in DNA very much like those created by the process behindantigen recognition."Hermes behaves more like the process used by the immune system torecogniz...UCSD Discovery Shows How Embryonic Stem Cells Perform 'Quality Control' Inspections
...entists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability...changes in DNA very much like those created by the process behindantigen recognition."Hermes behaves more like the process used by the immune system torecogniz...New therapy for HIV/AIDS eliminates needles and excessive toxicity
...entists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability...changes in DNA very much like those created by the process behindantigen recognition."Hermes behaves more like the process used by the immune system torecogniz...DNA Recombination and Repair—A New Twist to RecA Function
...e the repair of DNA lesions during replication—the process by which a DNA molecule is copied to make two. RecA is also an ATPase, an enzyme capable of hydrolyzing (breaking down) ATP, when bound to DNA. RecA uses ATP to carry out strand exchange over long sequences and impose direction to the exchange, to b...Gene sequencing explains bioremediation 'bug'
...entists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability...changes in DNA very much like those created by the process behindantigen recognition."Hermes behaves more like the process used by the immune system torecogniz...NC State scientist finds soft tissue in T. rex bones
...n of the journal Science, Schweitzer describes the process by which she and her technician, Jennifer Wittmeye...nerals from the T. rex femur fragment. The removal process left behind stretchy bone matrix material that, when examined microscopically, seemed to show blood ...Zebrafish may hold key to understanding human nerve cell development
...rafish is "seeded" withfuture hair cells through a process known as placode migration. Theseprecursor cells, called interneuromast cells, eventually go on to makehair cells, but only when they are sufficiently far enough away fromthe glial-ensheathed nerve."Once these cells are far enough away from the glia ...Harmful Bacterium Commonly Found in Poultry May Survive Refrigeration and Frozen Storage Combined
...rafish is "seeded" withfuture hair cells through a process known as placode migration. Theseprecursor cells, called interneuromast cells, eventually go on to makehair cells, but only when they are sufficiently far enough away fromthe glial-ensheathed nerve."Once these cells are far enough away from the glia ......rafish is "seeded" withfuture hair cells through a process known as placode migration. Theseprecursor cells, called interneuromast cells, eventually go on to makehair cells, but only when they are sufficiently far enough away fromthe glial-ensheathed nerve."Once these cells are far enough away from the glia ...First real-time view of developing neurons reveals surprises, say Stanford researchers
...synapses while others recede. This trial-and-error process is what establishes the final interconnected mesh ...into the mature form. "We're looking at a dynamic process that nobody has ever seen before," Smith said. Understanding how neurons mature into their adult ro...The Shapes Of Life: NIGMS Project Yields More Than 1,000 Protein Structures
...otein structure determination from a mostly manual process to a highly automated one. Robotic instruments rapidly clone, express, purify, crystallize, and analyze many proteins simultaneously, cutting the time it takes to determine a single protein structure from months to days. For example, a robotic arm dr...Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells
... see them in the old way requires a time-consuming process like fluorescent tagging or a chemical reagent. We...e functional cell type it eventually becomes. That process is a mysterious sequence of metabolic and genetic changes." There are, he says, metabolic similariti...