Genome-wide mouse study yields link to human leukemia
...ce, researchers found that methylation, a chemical process that adds methyl molecules to DNA, silenced a numb...hylated, appears to interrupt normal cell death, a process called apoptosis. "It's given us a whole new way to look at and possibly treat leukemia," says Mich...Novel Enzyme Shows Potential As An Anti-HIV Target
...protein–RNA) interactions—is highly regulated. One process that figures prominently in this regulation is acetylation, which adds an acetyl group (a molecule made of oxygen, hydrogen, and carbon) to a molecule or protein. Histone acetylation was long thought to influence transcription by regulating the struc...Scientists seek answers on what activates deadly anthrax spores
... of anthrax spore biology concerns the germination process through which the dormant spore becomes a reproductive, disease-causing bacterium," explained Al Claiborne, Ph.D., the principal investigator. "The potential importance of such a germination control mechanism in anthrax is clear, as spore germination...Live Recombinant Adenovirus Vaccine Technique Explored
... safe and effective. The researchers believe their process for constructing a replicating live recombinant adenovirus could lead to more economical vaccines that provide longer-lasting disease protection, which would be particularly beneficial for people living in the developing countries where resources are...... minutes to return. “They must have the ability to process low-frequency sounds into images just as dolphins do with high frequency sounds, and they must have remarkable acoustic memories just as we have visual memories,?says Clark. Clark concludes that he and other researchers have been thinking about whal...Dinosaur DNA? New Patent Covers Degraded DNA recovery
... from which to multiply the genetic material. That process is repeated until the genetic material is substantially representative -- at microscopic levels -- of the species from which the degraded sample was obtained. Dr. Ensley and his team hope to apply this new technology to products they will make avail...Gene therapy converts dead bone graft to new, living tissue
...n't raid their bones for the calcium it needs. The process works both ways, fortunately, as another set of ce...ild 10 percent of his or her bone structure. This process of teardown and rebuilding is triggered in the dead bone when Schwarz paints it with the genetically...Sea skate experiment sheds light on human cell transport
...cles are inserted into the membrane and a chemical process known as phosphorylation takes place. This activates the gates, which open to release excess water along with salts and other organic material. The researchers made their discovery by using a plant-based substance to block an enzyme that causes phos...Color-blind method opens new doors in DNA sequencing
...ion base pairs, and 'DNA sequencing' refers to the process scientists use to read out the order of those nucl...ion. "Genome sequencing, by its very nature, is a process that begs for precision, and the number of mistakes that can be tolerated is extremely low," said Cu...Automatic extraction of gene/protein biological functions from biomedical text
...method for automatically extracting the biological process functions of genes/protein/families based on Gene Ontology (GO) from text using a shallow parser and sentence structure analysis techniques. When the gene/protein/family names and their functions are described in ACTOR (doer of action) and OBJECT (re...Enzyme allows B cells to resist death, leading to leukemia
...show that inhibition of Lyn was able to restorethe process of cell apoptosis to normal and treatment of malignantcells with drugs that induce cell death decreased both Lyn expressionlevels and activity ?suggesting a direct correlation between high Lynactivity and the ability of these B cells to resist apopto...Gene variations explain drug dose required to control seizures
...y College London. Patients often undergo a lengthy process of trial and error to find the dose of anti-epilep...epsy with phenytoin can be a difficult and lengthy process because of the wide range of doses required by different patients and the drug's narrow therapeutic ...Solution to Pollution: New Bacteria Eats Toxic Waste
...esearchers will then participate in the annotation process by which genes in the sequences will be identified. The researchers will be able to understand the genetic material that allows these bacteria to degrade the PAHs and survive in the soil. Such knowledge may help researchers better understand and util...Enzyme shown to help protect genomic stability
...ession. It is the complex activity governing this process to which Ubp10 contributes. Enzymatic modifications to histones control DNA activation or silencing through the addition or removal of acetyl, methyl, and ubiquitin molecules in prescribed sequences and patterns. One job of Ubp10, as identified in th...Needling Chromosomes Reveals Cell Division Secret
...house its genes. They replicateand separate in the process of cell division. The exquisite management of adh...ucial if the cells are to divide properly. In this process chromatids are drawn apart to separate poles of the dividing cell so that each new "daughter" cell c...Poplar trees redirect resources in response to simulated attack
...tes that incorporated the C-11 radiotracer via the process of photosynthesis one hour later. Panel A shows the distribution of carbohydrate in the untreated plant (red is high; blue is low). Panel B shows that when that same plant is retested after exposure to jasmonic acid, a potent plant hormone that makes...Researchers identify target for cancer drugs
...hosphate group to a sequence of its amino acids (a process called "phosphorylation"). This process occurs not only in human cells but in other organisms such as the fruit fly. Finding this complex co...Plant hemoglobins: Oxygen handlers critical for nitrogen fixation
... nitrogen in the root nodules of legumes through a process that is conceptually not unlike that undertaken by mammalian hemoglobins in facilitating oxygen transport and exchange in the blood. The most conspicuous plant hemoglobins are the symbiotic hemoglobins of legumes; these hemoglobins accumulate in roo...Vital step in cellular migration described by UCSD medical researchers
..., cell migration is a complex, extremely important process that is not completely understood by researchers. In order to move, a cell must be polarized so that the molecular processes at the front end and back end are different, leading only to forward movement. One of the first steps in cell migration is th...Weill Cornell Research Reveals Secrets Of Trafficking Within Cells
...hers throughout the body -- depends on an internal process called endocytosis to keep the flow of cellular nutrients and information healthy and strong. It's an incredibly important life process, and now researchers at Weill Medical College of Cornell University in New York City have used an exciting new te...