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Tag: "process" at biology news

A gene's first 'kiss' sets off that affair known as puberty

...volved, just how and when the brain activates this process has been a great mystery. An appreciation of puberty's deep-seated neurobiological mechanisms could, for instance, help prevent precocious or delayed puberty from occurring in some children," noted the study's lead author, Tony Plant, Ph.D., a profes...

DNA Molecules Used To Assemble Nanoparticles

...ch as contrast agents and drugs, but the synthesis process is long and difficult, requiring months for each new molecule added to the dendrimer in sequential steps. And the yield of useful particles drops with each successive step of synthesis. For a paper published Jan. 21 in the journal Chemistry and Biol...

UAB scientists discover the origin of a mysterious physical force

...omedical research, since a substantial part of the process of designing new drugs is based on understanding how substances penetrate cell membranes to enter cells. These drugs are often proteins designed to prevent or strengthen the action of other substances. In these cases, accurately identifying the prote...

Quantum Dots Research Leads to New Knowledge about Protein Binding in Plants

...essesinvolved, namely the network of the signaling process in plantreproduction,?said Ozkan. "A better understanding of the interactionof SCA with pollen tubes could help with successful plant breeding?...

Source of molecular triggers in cutaneous T cell lymphoma identified

...sed during normal cell death. As cells undergo the process of apoptosis, cryptic -- or masked -- antigens, are uncovered. Those newly available antigens are presented by LC directly to CTCL receptors, stimulating the malignant cells rapidly divide. "This finding has broad implications for the understanding,...

Enzyme, lost in most mammals, is shown to protect against UV-induced skin cancer

...se lesionsthrough a much less direct and elaborate process called nucleotideexcision repair.In the new work, Dr. Bert van der Horst and colleagues studied theeffects of CPD and 6-4PP lesions by providing mice with transgenesencoding CPD and 6-4PP photolyase enzymes.Although mice do not ordinarily produce the...

Novel technology detects human DNA mutations

....To do so, Nanosphere scientists employ a two-step process calledClearReadTM technology. This method sandwiches a target DNA SNP segment between two oligonucleotide sequences to greatly increase detection specificity and sensitivity. One segment identifies any mutations in the DNA and the probe, a highly sen...

Priming embryonic stem cells to fulfill their promise

...Universityof California, San Diego have invented a process to help turn embryonicstem cells into the types of...e embryonic stem cells to beginthe differentiation process into liver cells. Bhatia, Chien, and Flaimdesigned the technique with other cell biologists in mind ...

Growth in the sea comes down to a struggle for iron

...regations. They studied the sinking rate, the slow process through which aggregations of diatoms sink into the deep sea, taking their carbon with them. The Kilo Moana returned to Hawaii after spending 42 days at sea. Early results suggest that the struggle for iron may indeed follow something like what happ...

Lack of enzyme turns fat cells into fat burners

...adds another tissue or organ that helps out in the process ofenergy maintenance," said Wakil. "ACC2 is potentially a key enzyme inthe regulation of weight, obesity, and related problems."Wakil and his colleagues studied the oxidation of fatty acid andglucose in cultures of fat cells isolated from both normal...

Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs

...y repairing the diseasedblood vessels. This repair process results in improved circulation evenduring exercise. Some people are not able to repair their own vessels,however, and physicians don't completely understand the reasons why.Recent studies show that when muscles do not receive enough blood, thebody m...

Fox Chase Cancer Center scientists identify immune-system mutation

...e underlying molecular pathways that regulate this process have remained obscure. "The mutant HD mice are unable to generate mature helper T cells, even though their immature T cells carry the CD4 protein," Kappes explained. "Instead, the mutation redirects them to the killer-cell pathway. "Our new study i...

Drug That 'Tags' Decision-making Areas Of The Brain May Aid

...s, a senior citizen learning to play piano, or the process ofaddiction following repetitive exposure to specific drugs. Thesebehaviors all result from the formation of new connections betweenindividual neurons or modifications of existing connections in thebrain.“Imaging of nicotine receptors also gives us t...

Plants, animals share molecular growth mechanisms

...edge of the biochemical reactions involved in this process eventually may allow researchers to design plants better able to protect themselves from insects and disease. "These genes and their proteins are required for normal development and for normal cell-to-cell adhesion," Szymanski said. "They affect the...

Researchers Uncover Key Step In Manufacture of Memory Protein

...ol-rich molecules known as lipids. If this binding process does not take place, proBDNF cannot be converted to its active form. Dr. Loh explained that the proBDNF molecule has four projections, resembling prongs. These prongs fit into a corresponding indentation on CPE, analogous to the way a plug for an ele...

Affymetrix Unveils Plans to Double Plant and Animal Genome Microarray Offering

...ed using the samereliable design and manufacturing process that have made Affymetrix theindustry-standard technology for gene expression analysis. Over thepast ten years more than 3,000 papers have been published usingGeneChip technology. For more information, please visitwww.Affymetrix.com....

Computers to be used to find blueprint for new influenza drug

...ormally drugs are produced by trial and error in a process that can take many years. Professor Williams and his colleague Dr Gus Ruggiero will use part of the grant from the Biotechnology and Biological Sciences Research Council to buy computers with a combined power many times that of the most advanced des...

Inexpensive, mass-produced genes core of synthetic biology advances at UH

...ofresearch avenue, speeding the slow (and tedious) process of genecloning, or gene modification (mutations, deletions, etc). Devices the size of a pager now have greater capabilities thancomputers that once occupied an entire room. Similar advances are beingmade in the emerging field of synthetic biology at ...

New Technique for Tracking Gene Regulators

...l Laboratory. The techniquecould greatly speed the process of unraveling the role these proteinsplay in turning on and off the genes that establish the very identityof cells ?be they brain cells, liver, or blood ?as well as what mightgo awry in certain conditions like cancer. TheBrookhaven scientists, toget...

Bound for destruction: Ubiquitination protects against improper Notch signaling

... cell membrane must first beinternalized through a process known as endocytosis before they can bedigested by the proteasome, and indeed other types of ubiquitin ligasehave been shown to operate in the endocytosis of ligand-activatedNotch.The group first showed that an increase in nedd4 activity resulted int...

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