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Tag: "probe" at biology news

In nature, proteins sweep up nanoparticles

...atial-resolution imaging tool called secondary ion probe spectrometry, which is located at the Department of Energy’s Lawrence Livermore National Laboratory. Also called NanoSIMS, the tool determines the quantitative elemental and isotopic composition of a sample’s surface. To their surprise, they found...

3-D ultrasound scanner provides in-depth view of the brain

...tp://www.pratt.duke.edu/news/"id=417). To make the probe more suitable for brain scanning, the researchers ...said. Rather than capturing a side view, the brain probe "looks" straight ahead by emitting ultrasound waves like water from a hose. That way, it can produce...

Newborn neurons like to hang with the 'in' crowd

...ons sent out dendritic filopodia—tiny feelers that probe the environment. "When we analyzed them in three dimensions, the tip of the filopodia was preferentially associated with synapses already connected to other neurons," explains Toni. However, as the new neurons matured, the tiny tips filled out and...

Gene mutation linked to cognition is found only in humans

...rs state. They note that further studies should probe the biological function of type II neuropsin in humans, as the extra 45 amino acids in this form may cause protein structural and functional changes. They note that in order to understand the genetic basis that underlies the traits that set humans ap...

Study offers clues to 'Broken Heart Syndrome'

...ion. This imaging test, in which a tiny ultrasound probe is threaded into the coronary arteries on the tip of a catheter, may show whether the patient has clogged arteries or unstable plaques that are not visible on coronary angiography. These findings will help guide long-term treatment. "Because we d...

Dinosaur hearing, listening to muscle noise, quieter cubicles

...o date in space missions, particularly the Huygens probe that landed on Saturn's moon Titan (3aPAb1). John...zarnecki@open.ac.uk ) will explain how the Huygens probe deployed a simple sonar system and speed-of-sound sensor to constrain the methane content on the pl...

Decoding protein structures helps illuminate cause of diabetes

... he adds, "We need tools that not only allow us to probe the molecular structures, but also look at how the structures change in time." Zanni's research group uses a method, known as two-dimensional infrared spectroscopy (2-D IR for short), that takes advantage of the restless nature of molecules and atoms...

Leeches ferry infection among newts

...infected newt, either the mechanical action of the probe or the anti-inflammatory chemicals injected by the leech, could be used by the parasite as a cue to release its packet of spores. The spores could then latch on to the leech's proboscis, and the infection would be passed along to the next newt the le...

Scientists find genes involved in the battle between Hessian flies and wheat

...upt the insects' gut function. "The larvae probe the plant to open a sustained feeding site," said Jonathan Neal, a Purdue entomologist and another author of the paper. "Resistant plants block the larvae from establishing a feeding site. It's as if larvae keep trying to open doors because they are ...

Loss of a universal tRNA feature reported

...uter script ?specifically written by the group ?to probe the tRNA genes in the alphaproteobacteria group. Examination of the corrected tRNAHis sequences revealed that a group of alphaproteobacteria fails to encode a G (guanylate) at the -1 position of the tRNA as all other bacteria do. Amplification and tR...

A new study of living cells could revolutionize the way we test drugs

...As soon as the yeast got a taste of the vodka, the probe registered an electrical signal. A drunken hiccup perhaps? "It was probably the last gasp of the dying cell," says Professor Geim. The researchers had added so much ethanol that it poisoned the cell. Although not the cardiogram they had hoped for,...

New protein inhibitor impedes growth of cancerous cells

...nion paper, Lenart et al. use BI 2536 as a tool to probe the functions of Plk1 in normal cells. The availability of a specific Plk1 inhibitor is particularly useful in this regard because Plk1 is needed for a variety of different cellular processes required for cell division, and a chemical inhibitor such ...

Rapid, Low-Cost DNA Testing

...ay determines whether a fluorescently-tagged short probe sequence of single-stranded DNA matches a sequence...nalyte. When it does not, the fluorescently tagged probe adsorbs on a gold nanoparticle and its fluorescence is quenched. If the probe sequence is able to hy...

New study sheds light on 'dark states' in DNA

...his is the first time scientists have been able to probe the "dark" energy state -- so called because it cannot be detected by fluorescence techniques used to study other high-energy states created in DNA by UV light. The study suggests that DNA employs a variety of means to dissipate the energy it absor...

ATR checkpoint-activating DNA structure

...system will enable us to control, quantitative and probe checkpoint signaling responses in unprecedented ways." Using Xenopus egg extracts as a cell-free system, the researchers found that single-stranded DNA annealed with primers specifically triggers the ATR-mediated checkpoint response. While many pr...

Scripps research study reveals structural dynamics of single prion molecules

...study. "Our research techniques can now be used to probe the structures of other amyloidogenic proteins. This could prove important in understanding the basic biology of amyloid formation, as well as in designing strategies against misfolding diseases." Interestingly, the new study revealed that yeast p...

Using brain scans, researchers find evidence for a two-stage model of human perceptual learning

...) technique that made it possible to more directly probe neuronal tuning than in previous studies. Investigators found that cars activated a particular region in participants' brains, the lateral occipital cortex, which had also been found by other studies to be important for object recognition. Then t...

Twin studies reveal genetic components leading to cardiac and kidney disease

...tem and inflammation, suggesting new strategies to probe the role and actions of this pathway in inflammation. This study was published in the February 2007 issue of the Journal of Hypertension. Genes and Vascular Disease In a study on line in advance of publication in the May 1 edition of Circulat...

Triplex assay used to assay duplex genomic DNA

...ate. "We have decided not to focus on improving probe chemistry at this time, but rather to develop a flow injection based instrument which is matched to our chemistry," continued Daksis. Their Genome Flow® instrument, which employs hardware from FIALab Instruments of Bellevue, Washington, has one movin...

Speeding 'fingertip' discovery -- 20 years of protein info in 1 place

...ay too hard to work with. Now we have the tools to probe further,?he says. ...

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