Neural bottleneck found that thwarts multi-tasking
...at a central "bottleneck" exists in the brain that prevents us from doing two things at once. Dux and Marois are the first to identify the regions of the brain responsible for this bottleneck, by examining patterns of neural activity over time. Their results were published in the Dec. 21 issue of Neuron. "...NIH announces phase III clinical trial of creatine for Parkinson's disease
...ide cells. It also may act as an antioxidant that prevents damage from compounds that are harmful to cells in the brain. In a mouse model of PD, creatine is able to prevent loss of the cells that are typically affected. "Creatine, or any compound that may slow the progression of PD, could have very impor...Scientists unlock mystery of embryonic stem cell signaling pathway
... from interacting with the protein ß-catenin; this prevents the stem cells from being ‘told?to differentiate into a more specific cell type. At the same time, IQ-1 enhances the interaction between the coactivator CBP and ß-catenin, which signals the cells to keep dividing and to remain as fully potent stem ce...UCLA scientists design masks to hide genetic mutations from cell
...to camouflage each abnormal splice. The technique prevents the cell from seeing the genetic defects and restores splicing to the correct location in the gene. IMPACT: The laboratory findings suggest a powerful new approach for treating cancer and other diseases caused by genetic mutations. The research...Erectile dysfunction in diabetes is due to selective defect in the brain
...NO synthase with NG-monomethly-L-argining (L-NMMA) prevents NMDA-induced erection. The researchers hypothesized that the blunted NMDA mediated responses in diabetes reflects an impaired NO mechanism within the PVN. The involvement of an NO mechanism in the NMDA mediated behavioral response was also explored. ...Scientists unveil piece of HIV protein that may be key to AIDS vaccine development
...ry molecules. This nearly impenetrable sugar cloak prevents antibodies from slipping in and blocking the proteins the virus uses to latch onto a cell and infect it. In 1998, Dr. Kwong and colleagues published the first X-ray snapshot of the core of HIV gp120 as it attaches to a cellular receptor known a...Gene that makes people 'early to bed and early to rise' demystified
...dditional evidence that the lost "phosphorylation" prevents a cascade of chemical modifications that are normally primed by the initial event. Moreover, they show that the human gene inserted into otherwise normal mice causes them to rise early, symptoms that mirror those in people with FASPS. In contrast,...Cartilage discovery offers arthritis hope
...f the structure of these fibrils, a treatment that prevents them deteriorating would always prove elusive," said Professor Kadler. "This research, while just a beginning, at least establishes some basic scientific facts that could prove useful in future studies on osteoarthritis and related conditions." T...Scientists discover how body fights to control spread of cancer
... forms a protective shield around cancer cells and prevents them from causing secondary tumours, is attacked b...ical Sciences, explains: "MUC1 on the cell surface prevents the cancer cells from attaching to the blood vessel wall which causes secondary tumours. We have di...Secret of worm's poison pill box protein could produce new natural insecticide
...ct. The toxin not only kills the target insect but prevents other predators from eating the body giving free reign to the nematode worms to consume it, multiply and move on. However, until now, researchers had little idea of the make up of XptA1 and thus how it worked. The research team, based at the Univers...Africa's first large-scale HIV vaccine study launches
... researchers to determine whether the test vaccine prevents HIV infection, results in lower HIV levels in those who become infected after vaccination or both. In addition, investigators for the South Africa vaccine trial will determine if this vaccine, which is based on clade B HIV, has the potential to prote...Synthetic peptide targets latent papilloma virus infections
... a protein fragment, or peptide, that successfully prevents the virus from hitching a ride on a cell's chromosomes as the cell divides. If such a peptide - or more likely, a drug that mimics the action of the peptide - works in the body, it would effectively stop the virus from spreading or generating warts, ...Fighting influenza & co. with 40,000 blood samples
... of the elderly the flu vaccine unfortunately only prevents the disease in six out of ten cases.' By contrast, with young adults, the success rate is as high as 90 per cent. The reason for this is that the effectiveness of the immune system decreases with age. An international research consortium now wants...Better assessment of transfusions could save blood
...C transfusions is an increased oxygen level, which prevents cellular injury. However, studies have not consistently demonstrated that the increased hemoglobin level with transfusion leads to improved tissue oxygenation. At this point in time, there are no convincing data to support the routine use of RBC tran...New compound prevents alcoholic behavior, relapse in animals by blocking stress response
...to stress effectively stops excessive drinking and prevents relapse. The new, synthetic compound, known as MTIP, also muted the anxiety that typically develops in rats experiencing the equivalent of a hangover. Such stress is linked with higher levels of a brain chemical called corticotropin-releasing facto...Discovery of 'master switch' for the communication process between chloroplast and nuclei of plants
... that ABI4, a known plant transcription factor. It prevents light-induced regulatory factors from activating g...a newly identified sequence motif, and by doing so prevents light-induced regulatory factors from activating gene expression. It has a role in so many signaling...Newly identified mechanism for silencing genes points to possible anti-cancer strategies
...rfere with the proper assembly of ribosomes, which prevents them from doing the work of translating messenger RNA into protein. "We wondered if certain microRNA-responsive genes might be attracting microRNAs that then recruited eIF6 to that location," Shiekhattar says. "If so, the eIF6 would prevent the as...The quest for an effective HIV vaccine presents new possibilities, challenges
A vaccine that prevents HIV infection remains an important goal in the fig...s. Johnston and Fauci conclude that a vaccine that prevents HIV infection by clearing the virus before cells become latently infected remains the goal. In addit...Herpes infection may be symbiotic, help beat back some bacteria
...erging from latency. If the virus stays latent, it prevents itself from seriously endangering the host and can continue to spread to new hosts from its current perch. "We need to explore whether there are additional costs and benefits to the host from this," Virgin says. "Are there additional pathogens tha......ation of biomolecules, which is time consuming and prevents subsequent analysis. ...