Gut protein found to protect against infection and intestinal breakdown
...to bile in the small intestine may hold the key to preventing infection and intestinal breakdown in people with ...ment." When the bile ducts of mice were tied off, preventing bile from reaching the intestine, adding GW4064 prevented damage to the intestines, showing that it ...Scientists develop malaria forecasting tool to predict disease risk
...l will assist doctors and health care providers in preventing and controlling the disease. Malaria is one of the world's deadliest diseases, killing more than one million people every year, as well as infecting a further 500 million worldwide. The mosquito-borne illness is endemic in several regions globall...New study shows benefit of early therapy in HIV-infected infants
... mothers revolves around balancing the benefits of preventing disease progression and the risks and costs of life-long therapy begun within months of birth. Policies on when to start ART vary across Europe. Up to this point, the effect of age on clinical outcome has been difficult to assess because CD4 cell co...Bone and cartilage growth to blame for heart valve disease
... valves. Therefore, research has never focused on preventing the problem," says Dr. Rajamannan. "Currently the...pies such as statins may be able to play a role in preventing or slowing the process and curtailing the need for surgery." Valvular heart disease is on the rise ...Genetically engineered mosquitoes show resistance to dengue fever virus
...comes vulnerable to dicer-2 and is cut up, thereby preventing further virus replication. On its own, this process of self-destruction happens only after the virus has already replicated and been transmitted; however, the researchers found a way to control and speed up the process. They accomplished this by clo...'Shuttling' protein possibly key to resilience of cancer cells
...heterodimer, the nuclear export signal is blocked, preventing ATF2 from traveling from the nucleus to the cytopl...y of cancer cells to resist cancer treatments, and preventing the ATF2 from moving into the cytoplasm might improve the effectiveness of anticancer treatments. "...Hopkins researchers discover genetic switch that turns off an oxygen-poor cell's combustion engine
...emonstrated that HIF-1 shuts down the TCA cycle by preventing an enzyme called PDH from converting pyruvate made by glycolysis into acetyl CoA. Specifically, HIF-1 blocks the ability of PDH to make this conversion. HIF-1 does this by activating a protein called PDK, which binds to PDH and prevents it from perfo...Groovy protein essential for promoting cancer development
...yme tends to clump together once outside of cells, preventing it from forming the ordered crystals necessary for structural studies. Scientists from Cech's lab and others had tried to simplify matters by crystallizing a portion of the protein, but the segments that they selected clumped together just as stubbor...Report lists top 20 most-vulnerable African carnivores
...yme tends to clump together once outside of cells, preventing it from forming the ordered crystals necessary for structural studies. Scientists from Cech's lab and others had tried to simplify matters by crystallizing a portion of the protein, but the segments that they selected clumped together just as stubbor...Study indicates dramatic rise in antibiotic-resistant community-acquired staph infections
...antime, the CDC's fact sheet on MRSA suggests that preventing MRSA may be as simple as employing the tried and true cure of soap and water: "Practice good hygiene," is its primary advice. ...Possible brain hormone may unlock mystery of hibernation
...ent of hypothermia treatment that is effective for preventing brain ischemic damage." In cryosurgery, physicians use extreme cold to destroy abnormal tissue, such as cancerous tumors. ...Imaging study links key genetic risk for Alzheimer's disease to myelin breakdown
...(MRI) may prove useful in assessing treatments for preventing the disease. "Myelination, a process uniquely built up in humans, arguably is the most important and most vulnerable process of brain development as we mature and age. These new findings offer, for the first time, compelling genetic evidence that my...Proteins stop blood-vessel and tumor growth in mice
...and 5, slow the growth of cancer tumors in mice by preventing blood vessels from sprouting. The proteins are promising candidates for use in cancer therapy. "Healthy humans produce fibulin proteins, which regulate cell proliferation, migration and invasion. In the past, we have seen that they are depleted in ...Hopkins study suggests commercially available antibiotic may help fight dementia in HIV patients
...m the space between neurons (the synapse), thereby preventing excess neuronal excitation, which in turn can cause cell death and brain damage. Ceftriaxone, used to treat pneumonias, sexually transmitted diseases, bacterial meningitis and other infections, is a known stimulator of EAAT-2 expression and protects...Inflammation and drugs to control this activity studied in a variety of tumors sites
...s said. COX-2 inhibitors may also have effects in preventing other diseases, and his laboratory would like to e...flammatory effects also makes it more effective in preventing the development of potentially precancerous polyps in the colon. Sarah Daugherty, research fellow a...Mayo Clinic researchers discover cancer cells may move via wave stimulation
...ocess is the first step toward one day halting it, preventing it or reversing it therapeutically." Why Movement Matters Cell growth and movement are vital topics in cancer research because cancer is a disease of uncontrolled cell growth in which the normal balance between growth promotion and growth inhibitio...Trial success for diabetic nerve therapy
...s massive potential for managing the condition and preventing thousands of foot amputations each year. "The vast majority of non-traumatic hand and foot amputations carried out in UK hospitals are caused by diabetes and there are currently no treatments available to prevent or slow the progress of nerve diseas......ases might aim at stabilizing prion aggregates. By preventing the aggregates from being broken up to smaller see...uced. In contrast, most such strategies now aim at preventing the proteins from forming in the first place," he said. In future studies, Weissman and his colleag...