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Tag: "prevented" at biology news

Pain killer fights breast cancer by targeting key enzyme

...are specific to breast cancer cells." The analogs prevented a crucial step in the aromatase production process in the breast cancer cells ?they stopped transcription, the first step in gene expression. Compared to other tissues, breast cancer cells use a slightly different signal to indicate when it is time t...

Ancient DNA helps UF researchers unearth potential hemophilia therapy

...more extreme symptoms of the disease, gene therapy prevented profuse bleeding in the animals, the findings show. More than 18,000 Americans, nearly all men, have hemophilia A, the most common form of the disease, according to the Centers for Disease Control and Prevention. Currently, the only safe treatment f...

Needle-free immunizations

...tion ?infection and disease ?are high and could be prevented with needle-free methods." Mitragotri says that he anticipates that needle-free methods will reduce the economic burden associated with needle-caused infections, eventually proving to be economically feasible. A wide range of interdisciplinary rese...

Access to existing medical treatments could save more lives than spending to improve the treatments

...pent on new generation drugs saved fewer lives and prevented fewer strokes than if the existing drugs had been ...etting aspirin to all eligible patients would have prevented more strokes than were prevented by developing more potent and more expensive antiplatelet drugs, Wo...

Plants, too, have ways to manage freeloaders

...teria were deprived of atmospheric nitrogen, which prevented them from sharing nitrogen with the plant. However, no one had asked whether plants could detect natural differences in nitrogen fixation among the microbes they encounter in the soil. Interestingly, not all plants seem to nodulate the best bacteria...

Scientists show how thinking can harm brain cells

...e and strokes. Pretreatment before exposure to PAF prevented dendritic beading and preserved synaptic functions, the studies showed. "Stressing the cells with small amounts could trigger protective genes and induce adaptations that will make the dendrites more able to withstand insults," Bellizzi said. Diazo...

In SAD patients, autumn antidepressants can prevent winter depression

...tic studies that indicate that SAD can actually be prevented in some patients by starting antidepressants early...pse is somewhat predictable and the symptoms being prevented can be highly distressing and debilitating," comments Dr. Rosenthal. "In my opinion, the treatment ...

Discovering the first steps in transcription-coupled repair

... found that RNAPII bound to a transcription bubble prevented incision by XPG. To their surprise, however, adding another large protein machine called Transcription Factor IIH (TFIIH) allowed XPG to cut the DNA strand at the appropriate place -- without removing the RNAPII. The best explanation is that TFIIH ca...

Sperm stem cells closer to being like embryonic stem cells

New experiments that prevented rat sperm stem cells from changing permanently into sperm have brought researchers one step closer to coaxing such cells to behave like embryonic stem cells, capable of growing into many other types of cells in the body. Researchers at the Cecil H. ...

Small molecule inhibitor of cholera discovered

... They then showed that the most promising compound prevented cholera bacteria from setting up an infection when introduced into the digestive tract of mice. Since most disease-causing organisms use elaborate virulence factors such as toxins to do their damage, the new approach should be widely applicable. "T...

Molecular cabal contributes to stroke damage

... neurons that drugs that inhibited NMDAR or CaMKII prevented the ischemia-induced enhancement of ASIC sensitivity, as well as neuronal death. "In summary, our report provides a functional linkage between NMDAR-mediated exitotoxicity and ASIC-mediated acidotoxicity induced by ischemia, which is known to cause ...

Prostate cancer uses Wnt signaling proteins to promote growth of bone tumors

...lytic changes associated with bone resorption also prevented prostate cancer from establishing itself in bone. By learning how DKK-1 blocks Wnt's signal to prostate cancer cells, they hope to learn how to control physical changes in bone that encourage the development of metastatic tumors. "Our goal is to fin...

Wright bros. upstaged! Dinos invented biplanes

...s gave strength and flexibility to the feather and prevented air from passing through it in flight. Some present-day birds, especially raptors as well as the earliest Jurassic bird Archaeopteryx, also have (or had) feathers on their legs, Chatterjee says. But these are not flight feathers and appear adapted ...

Wolves' top-down effect

...nearby town of Banff has been steadily growing and prevented wolves from fully recovering in areas surrounding the town while wolves fully repopulated adjacent areas. Hebblewhite and his fellow researchers were able to examine the effects of wolf exclusion on elk--wolves' preferred prey--on plants such as will...

Scientists develop fungus-fighting vaccine

...ibodies stuck to the invading fungal cell wall and prevented the fungus from growing. The authors now plan to test the vaccine in humans and hope the results are equally promising. ...

Anti-cancer Compound In Beer Gaining Interest

...eted at the early stages of cancer development and prevented by long-term exposure to non-toxic nutrients, food supplements or drugs that prevent the formation of cancers. With its broad spectrum activity, presence in food products, and ability to inhibit cancer at low concentrations, xanthohumol might be a go...

Chernobyl: The true scale of the accident

...r crops, clean feeding and use of Cs-binders (that prevented the transfer of radiocaesium from fodder to milk) led to large reductions in contamination and permitted agriculture to continue, though some increase in radionuclide content of plant and animal products has been measured since the mid-1990s when eco...

Amphetamines reverse Parkinson's disease symptoms in mice

...e unable to recycle dopamine with a drug that also prevented them from manufacturing the brain messenger. The brains of the mice therefore lack detectable levels of dopamine and the animals exhibit all the symptoms of Parkinson's disease for up to 16 hours. Those symptoms included severely impaired movement, r...

Scientists crack 40-year-old DNA puzzle and point to 'hot soup' at the origin of life

...hape in high temperatures, this suggests that heat prevented them from being acquired by the code at some point in the past. One possible reason for this is that the Last Universal Common Ancestor (LUCA), which evolved into all life on earth, lived in a hot sulphurous pool or thermal vent. As it moved into co...

K-State professors discover enzyme responsible for creation of a beetle's hard shell

... the process of hardening and pigmentation, can be prevented in the red flour beetle, Tribolium castaneum. A p...," Kramer said. "When we knocked out laccase-2, we prevented tanning from taking place." When the laccase-2 gene was not expressed, the newly formed cuticle rem...

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