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Tag: "prevented" at biology news

Gene that makes people 'early to bed and early to rise' demystified

...ly present at position 662 is replaced by glycine, prevented a regulatory enzyme from tacking a phosphate onto the encoded protein. Now, the researchers report additional evidence that the lost "phosphorylation" prevents a cascade of chemical modifications that are normally primed by the initial event. Mo...

Trojan horse strategy defeats drug-resistant bacteria

...searchers showed that gallium killed microbes, and prevented the formation of biofilms. Importantly, gallium's action was intensified in low iron condition, like those that exist in the human body. Gallium was even effective against strains of Pseudomonas aeruginosa from cystic fibrosis patients that were res...

Gallium: A new antibacterial agent?

...ted from individuals with cystic fibrosis. Ga also prevented P. aeruginonsa forming biofilms, the multi-cellular bacterial communities responsible for chronic bacterial infections, and killed both free-living bacteria and bacteria in biofilms. Furthermore, inhalation of Ga protected mice from both acute and ch...

Napoleon's mysterious death unmasked, UT Southwestern researcher says

...from the island, his terminal condition would have prevented him from playing a further major role in the theater of European history," said Dr. Robert Genta, professor of pathology and internal medicine at UT Southwestern and senior author of the study. "Even today, with the availability of sophisticated surg...

Protein found to shield pancreatic cancer cells from self-destruction

...arch also shows that the self-consuming cell death prevented by TG2 is independent of a prominent molecular pathway also known to regulate autophagy called the mammalian target of rapamycin. "Targeting TG2, or its activating protein PKC, or both, presents a novel and potentially effective approach to treati...

Inhibiting blood to save the brain

...irst episode of paralysis using the fibrin peptide prevented subsequent relapses. It also prevented further microglia activation and damage to myelin in the diseased mice, allowing them to survive wit...

Study of planarians offers insight into germ cell development

...erference immediately after the planarians hatched prevented the emergence and development of germ cells. Blocking nanos in mature adults caused their ovaries and testes to disappear. And when the researchers blocked nanos expression in planarians that had had their bodies and reproductive organs detached from...

Viral protein is an effective preventative against infection

...ude show that middle ear infections in mice can be prevented by giving the mice a lysin ?a protein derived from a virus that infects bacteria. The new technology may prevent children with the flu from developing secondary ear infections and would be an attractive alternative to traditional antibiotics, to whic...

Ocean's 'twilight zone' may be a key to understanding climate change

...reaches the deep ocean, where it can be stored and prevented from re-entering the atmosphere as a green-house gas, the oceans may have little impact on changes in the atmosphere or climate. The research is the result of two international expeditions to the Pacific Ocean, and is published in the April 27, 2007...

Dinosaur extinction didn't cause the rise of present-day mammals, claim researchers

...al species were relatively few in number, and were prevented from diversifying and evolving in ecosystems dominated by dinosaurs. The tree of life shows that after the MEE, certain mammals did experience a rapid period of diversification and evolution. However, most of these groups have since either died o...

Decoy pill saves brain cells

...Xu, reversed the outcomes. By tricking calpain, it prevented damage to the receptor and allowed the beneficial reaction to continue. In addition, it interrupted the feedback loop that stoked calpain activation. "This is potentially a treatment for any conditions that involve this kind of excitotoxicity," Ba...

Microbes compete with animals for food by making it stink

...y added. "If microbes could produce chemicals that prevented crabs or fishes from using these resources, then those microbes should gain an advantage and become more abundant." __IMAGE_2 As part of an interdisciplinary graduate training program funded by the National Science Foundation, Hay, two of his ...

Single molecule extends fat mice lives by reversing gene pathways associated with disease in obese

...ging. "After six months, resveratrol essentially prevented most of the negative effects of the high calorie diet in mice," said Rafael de Cabo, Ph.D., the study's other co-senior investigator from the National Institute on Aging's Laboratory of Experimental Gerontology, Aging, Metabolism, and Nutrition Unit....

Growth factor stimulates rapid extension of key motor neurons in brain

...that blocking the IGF-1 pathway in the spinal cord prevented the growth of CSMN axons, which confirmed the applicability of the in vitro experiments to living mammals. "The role of IGF-1 as a potent and specific enhancer of CSMN axon growth is highly relevant to our understanding of this critical populatio...

UCSF study will test new vaginal microbicide for herpes and HIV

...lecules are "caught" in the dendrimer branches and prevented from entering and infecting human cells, Moscicki said. To participate in the study, women must be between 18 and 24 years old, sexually active, healthy and free of any sexually transmitted disease. They cannot be pregnant or breast feeding. They ...

Mutant gene causes severe kidney disease in infants

...st of the PLCE1 mutations we identified apparently prevented podocytes from developing normally in the embryo, so defects were present at birth. A milder mutation seemed to interfere with repair mechanisms in the glomerulus, so defects didn't show up until later in life." U-M scientists used DNA microarrays...

Vaccination with embryonic stem cells prevents lung cancer in mice

...ed that vaccinating mice with embryonic stem cells prevented lung cancer in those animals that had had cancer c...er was just around the corner. "Cancer has been prevented and even cured in mice hundreds of times. At present, all I can say is that so far it looks good, an...

To slow AIDS in Russia, treat HIV-positive addicts, Stanford study says

...users was not the most expensive approach, but it prevented the fewest new infections, according to the study. Treating both populations equally provided the most health benefit for the money, said Owens. One key to implementing treatment programs will be keeping injection drug users on their HIV medicat...

Clue found to Epstein-Barr virus' ability to form and sustain tumors

...ein. Mutating the unique segment of amino acids prevented EBNA-1 from transforming resting B cells into proliferating cells. Under normal conditions, a cellular protein binds this 25-amino acid segment of EBNA-1, allowing transcription of viral and cellular genes regulated by EBNA-1 to occur. Hammerschmidt...

Need to pull an all-nighter?

...ulness. Blocking adenosine receptors with caffeine prevented this nitric-oxide-induced slumber. Rosenberg sees the most pharmaceutical promise in developing drugs that prolong wakefulness by curbing production of nitric oxide or scavenging the gas once it's produced. The opposite ?a sleeping pill made from n...

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