Cells use 'noise' to make cell-fate decisions
...noise level within the bacterial cells, they could prevent the cells' transformation between states, essentially "tuning" cellular behavior. "The amplitude of cellular noise correlates with the probability of triggering differentiation," Dr. Süel said. "This is experimental evidence that a genetic circuit...Leukemic cells find safe haven in bone marrow
...to block ASNS should be tested to see if they also prevent mesenchymal cells from making this amino acid. In addition, the ability of mesenchymal cells to make asparagine might be decreased by cancer drugs that are already known to disrupt the activity of those cells. "Because asparaginase is so widely u...Bacteria from patient's dental plaque causes ventilator-associated pneumonia
...oir of infection in these patients," said Heo. "To prevent opportunistic, hospital-acquired disease, taking care of teeth and gums while hospitalized might be especially important." ...Anti-herpes treatment reduces HIV levels in women infected with both viruses
...smit HIV are also required. A number of options to prevent HIV transmission are currently being investigated,...its. Importantly, an HSV vaccine that would either prevent HSV infection or diminish the clinical and sub-clinical manifestations of HSV with a similar efficac...Billions of dollars saved in US by polio vaccination
... translate into over 1.7 billion vaccinations that prevent approximately 1.1 million cases of paralytic polio... of vaccines not only as highly effective tools to prevent disease, disability, and death, but to provide enormous economic savings to society." Although t...Cracking open the black box of autoimmune disease
...lls called regulatory T cells. Regulatory T cells prevent biological "friendly fire" by ensuring that the T ...ow exactly how Foxp3 enables regulatory T cells to prevent autoimmunity. But the list of the genes that Foxp3 targets provides an initial map of the circuitry ...Viral protein is an effective preventative against infection
...irus that infects bacteria. The new technology may prevent children with the flu from developing secondary ea...e moment you come down with the viral infection to prevent the secondary infection, but physicians are reluctant to do this for fear of increasing resistance t...MicroRNAs can be tumor suppressors
...that shorten the 3?end of the HMGA2 transcript,and prevent let-7 binding, result in aberrantly high levels of... let-7 microRNA functions as a tumor suppressor to prevent cancer formation in healthy cells. ...Morphine makes lasting -- and surprising -- change in the brain
...mselves, would be effective targets for drugs that prevent or treat addiction....CSHL research ties harmless viruses to cancer
...ey cause may decrease the frequency of cancers and prevent their progression," said CSHL’s lead investigator Yuri Lazebnik. According to this model, cells can be made cancerous by viruses that fuse cells. Fusion abruptly unites two or three cells under the same membrane, a change that triggers massive CIN a...DNA layer reduces risk of reserve parts being rejected
...an be used for the application of DNA membranes to prevent post-operative adhesions, and in biosensors such as an implanted glucose sensor for diabetic patients. ...Ultrathin films deliver DNA as possible gene therapy tool
...or example, Lynn hopes to deliver genes that could prevent the growth of smooth muscle tissue into the stents, a process which can re-clog arteries, or that could treat the underlying causes of cardiovascular disease. Preliminary laboratory tests of the DNA-coated materials are promising. "The films sur...Scientists identify specific enzymes that make meningitis hard to fight
Two enzymes in meningitis bacteria which prevent the body from successfully fighting off the diseas...the DNA. Instead, it removes damaged DNA ends that prevent the DNA from being remade during the repair process. This has an important impact for our understand...Army research mission focused on autism
... for all children with autism and the knowledge to prevent it from ever happening in the first place," Redwood said....Reminding doctors which antibiotics to prescribe cuts C. difficile infection rates
...pectrum antibiotic, amoxicillin/clavulanate. To prevent future CDI rises as a result of the increased use of amoxicillin/clavulanate, a new narrow-spectrum policy was implemented as part of the hospital's clinical governance programme at the beginning of July 2001. This policy recommended less use of amox...Anti-dandruff compound may help fight epilepsy
...?switches fail in part due to protein defects that prevent potassium from exiting nerve cells and calming them. “Channels that carry potassium,?says Min Li, Ph.D., professor of neuroscience at Johns Hopkins, “must open on cue to make sure nerve cells only fire for defined periods of time.? In their studies...Light-based probe 'sees' early cancers in first tests on human tissue
...-cancer in epithelial tissues would therefore help prevent all types of cancer by catching it early, before it has a chance to develop further or spread." In some instances, the technique, known as "fa/LCI" (frequency-domain angle-resolved low coherence interferometry), might ultimately enable doctors and...Stem cell therapy shows promise in regenerating damaged muscle in heart attack patients
...art attack and are being followed for 2 years. To prevent bias, neither the patient nor the physician knows who received the stem cell treatment and who received placebo. Rush principal investigator cardiologist Dr. Gary Schaer, head of the Rush Cardiac Catheterization Laboratory, says one reason the stu...A first glimpse of the influenza replication machine
...oteins. Interfering with polymerase function would prevent the virus replicating, thereby reducing the spread...merase function could provide new ways to treat or prevent flu," says Cusack, "but this will require a detailed picture of the rest of the polymerase. This is ...Does a peptide affect the heart's response to social isolation?
...t regulates social behavior, has found that it can prevent detrimental cardiac responses in adult female anim...usions These findings suggest that oxytocin can prevent damaging cardiac changes in adult female prairie voles exposed to social isolation. While there are ...