New vaccine prevents CMV infection and disease in mice
...ented a strategy for developing a human vaccine to prevent against Human Cytomegalovirus (hCMV) infection and disease. CMV, a type of herpes virus, is the leading viral cause of birth defects and a serious problem in patients with compromised immune systems. The body’s natural immunity doesn’t protect ag...Experimental gene therapy 'abolishes' arthritis pain and lessens joint damage
... painkillers called opioids, which when they dock, prevent the sending of pain messages along nerve pathways. In the current study, researchers used gene therapy to increase by about one thousand times the number of opioid receptors expressed on the surfaces of nerve cells that carry pain messages back a...Avian influenza survivors' antibodies effective at neutralising H5N1 strain
... "We have shown that this technique can work to prevent and neutralise infection by the H5N1 'bird flu' virus in mice," says Dr Cameron Simmons, a Wellcome Trust researcher at the Oxford University Clinical Research Unit, Vietnam. "We are optimistic that these antibodies, if delivered at the right time an...First confirmed common genetic risk factors for breast cancer
...usceptibility. Normal versions of these genes help prevent cancer from occurring in the first place, by helping cells to repair DNA breaks and other abnormalities that can result from chance or exposure to an environmental toxin, such as excessive UV sunlight. However, BRCA-1, BRCA-2 and the other previously...Smallpox outbreak: How long would it take for vaccines to protect people? Would it work?
...e the immune system against smallpox. "Vaccines prevent disease by giving the body a jump-start at recogni..." Frey said. "We'd move in and vaccinate people to prevent the spread." Frey said this research compares the ability of a new investigational smallpox vacc...Resistant HIV quickly hides in infants' cells
...retroviral drug used to treat HIV infection and to prevent mother-to-child transmission. All had uncommon dru...with antiretrovirals in an unsuccessful attempt to prevent mother-to-child transmission found the virus quickly developed resistance, but levels of resistant v...Mice with a migraine show signs of brain damage
...or migraine sufferers to do everything they can to prevent their headaches. While avoiding severe pain has lo...ay the risk of brain damage makes it imperative to prevent the headaches, by avoiding a person’s triggers for the headaches and by using medications prescribed...Scripps research team sheds light on long-sought cold sensation gene
...uce cold sensation as an analgesic, or block it to prevent certain forms of chronic pain associated with cold sensation. "This study represents the first demonstration that a single gene is responsible for most cool temperature sensation," says team leader Ardem Patapoutian, who has joint appointments with ...'Insulator' helps silence genes in dormant herpes virus
...s boundary elements, are DNA segments that work to prevent a gene from being influenced by the activation or repression of its neighbors. About a dozen different insulator elements have been identified in organisms as varied as yeast, fruit flies, and humans. Not simply passive barriers, insulators help o...Scientists discover rare 'gene-for-gene' interaction that helps bacteria kill their host
...ry of defences that recognise and kill microbes to prevent infections from occurring. "Some remarkable dis...rs then used a technique known RNA interference to prevent the insects from producing the phenoloxidase enzyme. These insects were more susceptible to regular ...US control strategies may make flu epidemics worse, UCLA study shows
...population would need to be vaccinated in order to prevent a pandemic, none of these models have shown whether this critical coverage can actually be reached. What has been missing, according to Blower, a mathematical and evolutionary biologist, is the human factor. The human factor involves two biologic...Vaccine prevents prion disease in mice
An oral vaccine can prevent mice from developing a brain disease similar to mad cow disease, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 ?May 5, 2007. Prion diseases, which include scrapie, mad cow ...Keeping the immune system from starting a 'food fight'
After every meal, the body must prevent the immune system from launching an all-out fight ...gs. "If we could find ways to strengthen STAMP2 or prevent its suppression, the body might retain control," effectively unlinking chronic overeating and obesit...Nitric oxide: Key to cardiovascular and pulmonary function and drug effectiveness
...SNO compounds were administered to mice they could prevent the receptors from being "turned off" by the drugs. The researchers said these findings, if confirmed in humans, open up new avenues for the development of non-desensitizing drugs not only for heart failure and asthma but also for other conditions...Targeting sugar on blood vessels may inhibit cancer growth
In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego (UCSD) School of Medicine have targeted a sugar that supports blood vessel growth in the tumor. Their findings will be published in the May 7 on-line issue of Journ...UQ research heralds vaccine technology breakthrough
...to treat the illness in infected people as well as prevent against it. Those most at risk from RSV are chil... hospital with very worrying symptoms and it would prevent the death of the children who succumb to it and die." With preclinical modelling in mice having be...Risk of lymphoma increases with hepatitis C virus infection
... may lead to cancer. It might then be possible to prevent progression to lymphoma," said investigator Eric A. Engels, M.D., from the Viral Epidemiology Branch of NCI's Division of Cancer Epidemiology and Genetics. "More research is needed to further clarify the relationship between HCV infection and lympho...Warts vaccine -- 1 of many in pipeline
... smear program and currently available vaccines to prevent infections. Genital warts are transmitted by skin contact and the 2003 Australian Study of Sex and Relationships of 20,000 adults revealed four percent of people had had visible genital warts. Dr Jardine said men and women with genital warts wh...Baumann Lab defines proteins that distinguish chromosome ends from DNA double-strand breaks
...ded overhangs nor t-loop formation is essential to prevent illegitimate repair of telomeric ends," said Dr. Bae. "Instead, a short tandem array of telomeric repeats bound by a Rap1/Trf2 complex is sufficient to impede non-homologous end joining in a highly directional manner." It has long been understood ...Study shows continued success for new HPV vaccine against virus responsible for cervical cancer
... "It's the first vaccine designed specifically to prevent cancer," says Dr. Ault, one of the authors of the .... "The goal of the study was to see if we could prevent precancerous cases and we were 98 percent effective. Everyone who gets cancer goes through a pre-ca...