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Tag: "pressure" at biology news

NIH renews network focused on how genes influence drug responses

...n people's widely variable responses to high blood pressure drugs. (Julie A. Johnson, Pharm.D., University of Florida in Gainesville) Pharmacogenetics and Risk of Cardiovascular Disease --$14.8 million provided by NHLBI to determine the effects of gene variations on responses to statins, the most...

Gene therapy to lower blood pressure just enough

...into cells and enables that gene to maintain blood pressure at healthy levels for four months promises to take... of the National Academy of Sciences. "High blood pressure is one of the leading causes of death and disability in adults worldwide," said Dr. Bert O'Malley, c...

Gene controlling circadian rhythms linked to drug addiction

...kefulness, body temperature, hormone levels, blood pressure and heart activity, it may also be a key regulator of the brain's reward system. UT Southwestern researchers showed that, in mice, the Clock gene regulates the reward response to cocaine, suggesting that similar actions take place in humans. Finding...

Survival of heart patients on beta-blockers varies greatly with genetic variation

...eraction, slowing the heartbeat and lowering blood pressure to relieve stress on the heart. They also block im...ns of the genes influence such parameters as blood pressure response in hypertensive patients and heart function in heart failure patients. "But this is the f...

Envisat and ERS-2 reveal hidden side of Hurricane Rita

...ers to observe high-atmosphere cloud structure and pressure in the visible and infrared spectrum, while at the same time using radar backscatter to measure the roughness of the sea surface and so derive the wind fields just above it. Those winds converging on the low-pressure eye of the storm are what ultim...

Why do aneurysms form? New studies suggest leading role for white blood cells

...other AAA risk factors such as smoking, high blood pressure and inherited genetic vulnerability. The U-M researchers made the findings in laboratory experiments on mice that had been treated to wipe out their neutrophils temporarily, and in rats that lacked the protein that lets neutrophils attach to tissue ...

Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development

...t but it keeps closing on you until there's enough pressure in the airlock to allow it to open all the way." Melikyan explained, "The pore is an unstable structure at that moment: some pores will open and some won't. It's a crucial point in viral entry because it's critical for the pore to enlarge sufficient...

Use of high hydrostatic pressure to inactivate Hepatitis A virus in oysters studied

...ia Tech $119,000 to study whether high hydrostatic pressure will inactivate Hepatitis A virus in both shucked ... manager, will identify one or more effective high pressure processing schedules. The laboratory is a facility of the Department of Food Science and Technology ...

Gaining ground in the race against antibiotic resistance

...ing on in the doctor's clinic -- putting selection pressure on the enzyme by giving higher doses of antibiotic," said Vila. "The only ones to survive will be those that have an enzyme that can work more efficiently." The researchers conducted their experiments using a drug called cephalexin, a member of the...

Researchers develop gene therapy to reverse pulmonary arterial hypertension

...al hypertension (PAH)--a deadly form of high blood pressure in the pulmonary arteries caused by uncontrolled cell growth. Therapies are currently limited for a disease that can lead to heart failure and death within a few years. The researchers have shown that Survivin, a protein almost exclusively expressed...

Environmental lessons from tsunami as world's coastal population doubles

...pollution. But once these ecosystems are put under pressure by coastal development, they may lose their resilience. Similarly, if communities are more resilient they are going to be able to learn from past experience and to deal with disasters better and to recover quickly. Dr Neil Adger co author of the re...

Solution to 'legionella'

...trasounds by constructive interference generates a pressure front that produces a decompression of the gases d...uminous plasma around the bubbles, as well as high pressure and temperatures. These pressures and temperatures have two effects: on the one hand, they eliminat...

Enzyme affects hypertension by controlling salt levels in body

...enzyme known to cause hypertension increases blood pressure by activating tiny pores, or channels, in kidney c...sium supplements in order to keep their high blood pressure in check. The study will appear in an upcoming issue of the Proceedings of the National Academy of ...

Drugs from the deep blue

...ss the immune system, to treatments for high blood pressure and heart disease. Pessah's research group works with calcium channel modulators and other biomolecules derived from plants and scorpion venom. But when Pessah and Molinski got to talking at a party some years ago, they quickly realized that they co...

Tropical Deforestation affects rainfall in the U.S. and around the globe

...nt heat," said Avissar. "Associated changes in air pressure distribution shift the typical global circulation patterns, sending storm systems off their typical paths." And, because of the Amazon's location, any sort of weather hiccup from the area could signal serious changes for the rest of the world like dr...

Most embryos produced during IVF do not result in live births

... paradoxical situation," Patrizio added. "There is pressure to reduce multiple births, but we need to do so kn...ith the most potential. But addressing the growing pressure to transfer fewer embryos to reduce multiple births is a difficult task unless they can come up with...

Drug resistant avian influenza viruses more common in Southeast Asia than North America

... undergoing strong selective pressure." Selective pressure refers to the extent to which an organism has acqu...to prevent infection with H5N1 would put selective pressure on the M2 gene to acquire mutations that made it resistant to this antiviral drug. "H5N1 is now end...

Purdue researchers find key to rice blast fungus

...s bubble-like structure grows until it has so much pressure inside that it blasts through the plant's surface....orce, called turgor pressure, that is 40 times the pressure found in a bicycle tire," Xu said. "It's like driving nails through the plant surface." The researc...

Human brain is still evolving

...alin and ASPM showed significant changes under the pressure of natural selection during the making of the huma...n regulating brain size suggest that the selective pressure on the new variants may relate to cognition, Lahn emphasized that this possibility remains speculati...

Picky female frogs drive evolution of new species in less than 8,000 years

...such cross-breeding, there may have been selection pressure to evolve a mating strategy to minimize dead-end m...the theory is that this should create evolutionary pressure for the female choice to evolve so that they pick the right males," Moritz said. This so-called rei...

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