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Tag: "present" at biology news

Turning green gunk to gold, anti-cancer gold

...acycline, it can easily be done, but cryptophycins present more of a challenge. Sherman's team realized that with all cryptophycins, the most difficult step came very late in the synthesis, at the point at which a key part called an epoxide---a highly strained, three-membered ring oxygen-containing group, cr...

Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine

...s to each T cell type as it permits the B cells to present the peptide to the T cells in context with their own HLA class II. Herlyn and her group now plan to use the RPL8 antigen to develop a melanoma vaccine for patients with advanced disease. "And because the RPL8 antigen is expressed by breast cancer ...

Tumor-suppressor gene is critical for placenta development

...s also produced some mice in which the Rb gene was present in the placenta stem cells but destroyed in cells produced by them. These cells formed a normal-looking placenta and the embryos survived. "This suggests that Rb is important in maintaining placental stems cells, and that it plays a smaller or dif...

Infection detectives use disease 'fingerprints' to track common infections in children

...ways work because the bacteria or virus may not be present in the blood or other easily accessible area. Researchers at UT Southwestern, Children’s Medical Center Dallas and Baylor Institute for Immunology Research came up with a different approach ?analyzing the telltale "fingerprints" a disease leaves b...

Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription

...biological functions." In this work the authors present a calculation of the thermodynamic stability of DNA/DNA and mRNA/DNA duplexes across the genomes of four species in the genus Saccharomyces. The researchers found that genes of these organisms are more stable than intergenic regions near their 3?end....

Scientists sequence genome of parasite responsible for common sexually transmitted infection

...n. T. vaginalis also consumes bacteria that may be present in the urinary and genital areas, including the bacteria necessary for maintaining a normal healthy environment in the vagina. As a result, women infected with trichomoniasis become more susceptible to becoming infected by HIV and other STIs. In g...

Elucidation of the genome for diabetics with DNA chips

...ta cells of the pancreas. Zinc is a trace element present in very small amounts in the body, but essential for survival. Zinc deficiency is common in developing countries and has been associated with many diseases, including dabetes. These four genes may account for up to 70% of the hereditary basis of ...

Study to explore using magnets to correct 'sunken chest'

...ful recovery can take months. "The problem with present techniques is that they attempt to reshape the chest wall in one big operation," Harrison said. "A better idea is to apply a little force over a longer time, like the orthodontist moves your teeth." The use of the magnets has been deemed safe by t...

Canadian study shows bilingualism has protective effect in delaying onset of dementia by four years

...es this mean for the onset of dementia?" In this present study, researchers set out to answer that question by examining the diagnostic records of 184 patients who came to Baycrest's Sam and Ida Ross Memory Clinic between 2002 and 2005 with cognitive complaints. Of that group, 91 were monolingual and 93 we...

What's in the water? Estrogenic activity documented in fish caught in Pittsburgh's rivers

...riments to determine if estrogenic substances were present in the fish were performed in the laboratory of Pa...this study was that these estrogenic materials are present in such easily detected levels in local fish." According to Dr. Volz, the next step in this rese...

Cancer vaccines -- Taking a jab at cancer by stimulating the immune system

...: This is a placeholder abstract. Researchers will present follow-up efficacy data on an FDA-approved HPV vaccine. The full embargoed abstract will be available to reporters on Saturday, April 14. Analysis of the immunological response to a MUC-1 loaded DC vaccine for human pancreatic cancer: Abstract 48...

Gene that makes people 'early to bed and early to rise' demystified

...riant, in which the serine building block normally present at position 662 is replaced by glycine, prevented a regulatory enzyme from tacking a phosphate onto the encoded protein. Now, the researchers report additional evidence that the lost "phosphorylation" prevents a cascade of chemical modifications th...

Large size crucial for Amazon forest reserves

... in intact forest prior to destruction will not be present in a small fragment, but would they be found in an equally small plot surrounded by untouched forest? The answer to this question has profound management implications because it weights the relative importance of area and isolation in the design of f...

Genes and biomarkers that allow doctors to choose the right therapy for the right patient

...rican Association for Cancer Research, researchers present new biomarkers ?and techniques for determining biomarkers ?that could determine how an individual might respond to drug or radiation therapy. Molecular predictors of drug response in breast cancer: Abstract 4963 Researchers at Lawrence Berkel...

Warming oceans threaten Antarctic glaciers

... rise of less than 0.5 ºC could have triggered the present imbalance." Professor Duncan Wingham, at University College London, insists that the success of the research lies in the satellite instrumentation from which it is derived: "The extreme precision with which we can now make measurements of the Eart...

No carrier necessary: This drug delivers itself

...r of chemistry and a co-author. The nanocrystals present a major advantage over methods of delivery involving other carriers, according to Paras Prasad, Ph.D., SUNY Distinguished Professor in the Department of Chemistry in UB’s College of Arts and Sciences, executive director of the institute and a co-auth...

Scientists to track impact of Asian dust and pollution on clouds, weather, climate change

...ished by inserting into the cells a gene naturally present in green algae that "turns on" when exposed to light and enables the algae to swim toward the light. When the researchers shined light on the areas of the brain involved in smell, they could follow in real time what areas of the brain were reactin...

Common algae helps illustrate mammalian brain electrical circuitry

...ished by inserting into the cells a gene naturally present in green algae that "turns on" when exposed to light and enables the algae to swim toward the light. When the researchers shined light on the areas of the brain involved in smell, they could follow in real time what areas of the brain were reactin...

Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment

...hogenesis of lung injury in CF patients. They also present a new paradigm for treating CF. Specific inhibitors against the enzyme, in conjunction with current antibiotic treatments and supportive measures, might be a viable near-term approach to improving length and quality of life for many CF patients, befo...

Notorious cancer gene may work by destroying messenger

...d blood cells in infants and children. For the present study, Schoenberg and coauthor Yong Peng, a research associate in Schoenberg's laboratory, wanted to learn how PMR1 is activated to attach to mRNAs. They found that activation occurs when PMR1 is momentarily joined by an unidentified enzyme. Cont...

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