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Tag: "preliminary" at biology news

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

... the NCI’sDirector’s Challenge program set up this preliminary study to compareresults between labs. Twelve different tumor tissues, five cancer celllines, and five purified RNA samples were prepared, blinded, andrandomized for analysis in four laboratories: University of MichiganMedical School, Ann Arbor, Mich....

Newly discovered virus linked to childhood lung disorders and Kawasaki disease

...ly variedpathogenicity." Despite these encouraging preliminary observations, Dr.McIntosh noted that the association between this novel coronavirus andKawasaki disease will require confirmation by others in larger futureinvestigations....

Automatic extraction of gene/protein biological functions from biomedical text

...location similarities and rule-based techniques. A preliminary experiment demonstrated that our method has an estimated recall of 54?4% with a precision of 91?4% for actually described functions in abstracts. When applied to the PUBMED, it extracted over 190 000 gene–GO relationships and 150 000 family–GO relati...

Taking Aim With Nanoparticle PEBBLEs

...g over the past seven years, including encouraging preliminary results using PEBBLEs to treat a virulent form of brain cancer in rats. PEBBLEs are polymer spheres, typically 20 to 200 nanometers in diameter—about the size of a virus. The spheres carry an assortment of molecules on their surfaces, some to guide ...

NC State scientist finds soft tissue in T. rex bones

... are preserved as we think," says Schweitzer. "Our preliminary research shows that antibodies that recognize collagen react to chemical extracts of this fossil bone. If further studies confirm this, we may have the potential to learn more not only about the dinosaurs themselves, but also about how and why they w...

International trial of two microbicides begins

...multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, rep...

MetaChip provides quick, efficient toxicity screening of potential drugs

...multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, rep...

Devising Nano Vision for an Optical Microscope

...fraction of the wavelength of visible light. In a preliminary test of the embryonic technique, NIST scientists used violet light with a wavelength of 436 nanometers to image features as small as 40 nanometers, about five times smaller than possible with a conventional optical microscope. Roughly speaking, such...

Chemists identify key gene in development of type 1 diabetes

...sing target for its prevention and treatment." In preliminary studies by the research group, specially bred mice that lacked the gene for the MIF protein failed to develop diabetes compared to mice that possessed the gene, according to the investigators. Although it's likely that multiple genes are involved in ...

Vascular structure and function improve with diet and exercise

...ors for cardiovascular disease. The study reported preliminary data from the larger randomized Staged Nutrition and Activity Counseling (SNAC) trial. A Mediterranean-style diet has impressive cardio-protective effects, according to a 2001 American Heart Association scientific advisory. The diet is high in fruit...

Towards precise classification of cancers based on robust gene functional expression profiles

...sing target for its prevention and treatment." In preliminary studies by the research group, specially bred mice that lacked the gene for the MIF protein failed to develop diabetes compared to mice that possessed the gene, according to the investigators. Although it's likely that multiple genes are involved in ...

Antibiotic might fight HIV-induced neurological problems

...n antiretroviral treatment is effective. "If this preliminary observation holds up, minocycline could be really important for treating HIV infection in developing countries where access to traditional antiretroviral drugs is very limited," says Zink. "Most of the 40 million people with HIV infection live in the...

Potential treatments for neurofibromatosis

... symptoms of neurofibromatosis. They hope to begin preliminary testing in humans by the end of this year, and are experimenting with potential drug compounds now. Dr. Clapp, professor of pediatrics and of microbiology and immunology, said one target of their efforts will be mast cells, which are immune system c...

Researchers devise way to mass-produce embryonic stem cells

...hey differentiate into specific types of cells. In preliminary work, Ouyang has created a network of neurons from undifferentiated embryonic stem cells. The next step is to use human embryonic stem cells, and the researchers have yet to decide which line of stem cells to use.The mouse embryonic stem cells used ...

Polymers with copper show promise for implanted sensors

...with nitric oxide-releasing polymers has promising preliminary results with a new strategy: creating polymer coatings that generate nitric oxide from components already in the blood. U-M chemistry professor Mark Meyerhoff will discuss the work March 15 at the 229th national meeting of the American Chemical Socie...

Survey finds silver contamination in North Pacific waters

... Luoma said. The North Pacific survey completes a preliminary survey of silver throughout the world's oceans. The goal was to establish current levels of contamination as a baseline for future studies, Flegal said. "We found by far the highest levels of silver in the North Pacific. Even though the Atlantic Oce...

Researchers uncover sequence of major rice pathogen

...e at MIT, now called the Broad Institute, issued a preliminary genome sequence of M. grisea, and made it publicly available so other researchers could work to solve the problems rice blast presents. "That work decoded the string of letters that comprise the genome," Dean says. "This paper shows the work of the ...

Live vaccines more effective against horse herpes virus

...ky Derby, a Cornell University virologist says his preliminary research indicates that vaccines containing weaken...makes MLVs for equine herpes virus. Osterrieder's preliminary study compared the effectiveness of MLV vaccines to another more widely used vaccine for equine herp...

Scientists journey to southern Africa to unravel the secret world of elephant communication

...xperiment, O'Connell-Rodwell is able to make a few preliminary observations: "The data I've seen so far suggest that the elephants were responding like I had expected. When the '94 warning call was played back, they tended to clump together and leave the water hole sooner. But what's really interesting is that t...

wFleaBase: the Daphnia genome database

...lated bioinformatics tools. Over the coming year, preliminary genetic maps and the nearly complete genomic sequence of Daphnia pulex will be integrated into wFleaBase, including gene predictions and ortholog assignments based on sequence similarities with eukaryote genes of known function. wFleaBase aims to ser...

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