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Tag: "predictor" at biology news

Researchers use MRI to predict recovery after spinal cord injury

...Since the severity of spinal cord compression is a predictor of outcome after SCI, this study suggests that MRI may predict which patients would benefit the most from decompressive surgery," Dr. Fehlings said. He added that MRI should be performed on all patients with acute SCI whenever feasible as it prov...

'Personality-gene' makes songbirds curious

...ity. "The personality trait can be an important predictor of how individuals will respond to predictable and unpredictable changes in their environment and how well they cope with these changes", explains Bart Kempenaers. "If we want to understand the ecological and evolutionary importance of variation in p...

Sleep quantity affects morning testosterone levels in older men

...eep measured by polysomnography was an independent predictor of the subjects?morning total and free testosterone levels. "The results of the study raise the possibility that older men who obtain less actual sleep during the night have lower blood testosterone levels in the morning," said Penev. "Although t...

PET imaging shows young smokers quick benefit of quitting

...ary endothelial dysfunction is both "a significant predictor of cardiovascular events"—and reversible—its early detection is important, said Tamaki. PET—a diagnostic imaging test that measures metabolic activity and generates images of organ or tissue function?will continue to provide insight into coronary ris...

Gene signature assesses breast cancer outcomes

...und that the 70-gene signature was a more accurate predictor of disease outcomes than assessment with the Adjuvant Online! software. Moreover, statistical analysis indicated that most of the prognostic information provided by traditional risk classifiers was included in the gene classifier. The authors write...

Newly identified biomarker detects and regulates spread of brain tumors

...ly the tumor is likely to grow and spread and is a predictor of patient outcome. Low-grade tumors are slow growing and show little abnormality, whereas high-grade tumors are highly abnormal and grow and spread quickly, making treatment more difficult. Patients with highly malignant astrocytomas typically have ...

Beauty and the brain

...thing as follows: Like symmetry (another reliable predictor of attractiveness), prototypicality signals health and fitness ?unusually protuberant eyes might be a clue to disease, for example ?and so is a kind of shorthand for the value of a potential mate. But whereas that explanation makes intuitive sense...

A new view on Lyme disease: Rodents hold the key to annual risk

...rally lower than mice, their numbers were the best predictor of total nymph density in the subsequent year, lik...erall, the results found that acorns were the best predictor of Lyme disease risk--stemming from their crucial role in supporting white-footed mice, chipmunks, a...

AIDS vaccine research offers new insights on survival

... become infected with HIV may provide an important predictor of vaccine efficacy." Study coauthors include BIDMC investigators Yue Sun, M.D., Darci Gorgone, M.A., Adam Buzby, A.B., Jorn Schmitz, M.D., and Brianne Barker, A.B.; John Mascola, M.D., Ling Xu, M.D., Zhi-yong Yang, M.D., Bimal Chakrabarti, M.D., S...

'Signature' of chromosome instability predicts cancer outcomes

...y itself. This 25-gene signature was a significant predictor of clinical outcomes in a variety of cancers (breast, lung, medulloblastoma, glioma, mesothelioma and lymphoma). It could also differentiate between primary tumors and tumor metastases, and, in grade 1 and grade 2 breast cancer, distinguished the mor...

Viral genetic differences are possible key to HIV dementia

... neurotoxic variant of HIV, could we use that as a predictor of HIV dementia?" He says that such knowledge could also help care providers make "guided therapeutic decisions ?for example, the detection of particular viral genotypes may lead physicians to select for antiretroviral regimens that cross the blood-...

Alaska seal pup diet may hold key to decline of population

...Instead, the starting weight has been the critical predictor of whether the seal would add body mass and body fat, Polasek explained. Seals weighing less than 26 kilos (about 12 pounds) showed little progress in gaining weight and even lost blubber, regardless of which diet they were on. On the other hand, th...

AIDS-related cognitive impairment exists in two separate forms

...ost and easy to administer, appears to be a better predictor of relapse and disease-free survival than the Glea...ted a gene expression score that provided a better predictor of relapse than the Gleason score. "This gene expression score appears to give us additional prognos...

Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers

...ost and easy to administer, appears to be a better predictor of relapse and disease-free survival than the Glea...ted a gene expression score that provided a better predictor of relapse than the Gleason score. "This gene expression score appears to give us additional prognos...

Sweet 'water taste' paradoxically predicts sweet taste inhibitors

...phenomenon. We can now use sweet water taste as a predictor for potential sweet inhibitors." Sweet inhibitors are used by the food industry to counteract the undesirable high sweetness that results from replacing fats with sweet carbohydrates in reduced-fat products such as snack foods and salad dressings. ...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

... important role for microarray gene profiling as a predictor of clinical outcome in ovarian cancer, and could e...o gene profiles [CRP and OCPP] are a more powerful predictor of a patient's prognosis than either profile separately," says Cannistra. "This represents the first...

MicroRNA gene that regulates lifespan found by Yale scientists

...r studying the genetics of aging, and an excellent predictor of genes that also control mammalian aging. To test their functions, they made mutants in both of these genes. Animals with a loss-of-function mutation in lin-4 had a lifespan that was significantly shorter than normal, suggesting that lin-4 prevent...

Past illegal blood donation in China linked to hepatitis C virus infection

...ling blood or plasma was the strongest independent predictor for HCV-positive findings. Receiving a blood transfusion was also independently associated with HCV; villagers who received blood transfusion had about 8 times the risk of HCV infection than those who had no history of blood transfusion. Among the 5...

Weapon performance determines mating success in the collared lizard

... weapon performance (i.e., bite force) is a better predictor of fitness than body size and weapon size. The st...udy finds that bite-force performance was a strong predictor of reproductive success. However, no size measure was correlated with any estimate of mating success...

Eleven gene 'signature' reliably predicts cancer prognosis

...n primary tumors is a very consistent and powerful predictor of a short interval to disease recurrence, metastasis, and death after therapy in cancer patients diagnosed with ten distinct types of cancer. This work indicates that the presence of the conserved BMI-1-associated gene expression pathway that exist...

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