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Tag: "prediction" at biology news

Imaging Lymph Nodes with Nanoparticles

...important parts of thework up of patients for both prediction of prognosis and determinationof the most appropriate treatment. And an essential part of this workup is assessing whether or not there has been lymphatic spread. Currentmethods include surgical removal of nodes for examination and varioustypes of im...

Open microfluidic and nanofluidic systems

...an vary over a wide range of values. A surprising prediction of the new theory is that the experimentally observed polymorphism of the wetting liquid depends only on two parameters: (i) the channel geometry, i.e., the ratio of the channel depth to the channel width; and (ii) the interaction between substrate m...

MSI releases 'moleculizer' - a new approach to simulation of intracellular biochemical networks

...logy and chemistry to enableprecise, quantitative, prediction of the future behaviors of biologicalsystems.In keeping with the MSI's support for an open source biology,Moleculizer will be made freely available under the GNU Lesser GeneralPublic License.Nature Biotechnology is "a monthly journal covering the sci...

PANTHER Protein Classification System Database 5.0

...scientists with a unique resource for genefunction prediction and analysis based on a combination of advancedbioinformatics and manual data curation,?said Paul D. Thomas, SeniorDirector of Computational Biology for Applied Biosystems, PrimaryInvestigator for the development of the PANTHER system, and lead autho...

RNA project to create language for scientists worldwide

...n adopted internationally to advance RNA structure prediction and simulation and RNA sequence analysis. His work is supported by the National Institutes for Health and the American Chemical Society. Leontis describes RNA molecules as "the software controlling how the genes are expressed to make proteins." They...

US life expectancy about to decline, researchers say

...c policy as well. "One of the consequences of our prediction is that Social Security does not appear to be in nearly as bad a shape as we think," Olshansky said. "The obese may be inadvertently 'saving' Social Security, but the obese themselves and the health care system that cares for them will pay a very he...

Institute for Systems Biology Symposium Addresses Need for Better Computational Tools

...g current efforts to run Rosetta de novo structure prediction on World Community Grid, and applications of this new dataset to the reannotation of proteins of unknown function in over 60 complete genomes via de novo structure prediction. Other presenters included keynote speaker Dr. Nathan Myhrvold, Founder of ...

Global analysis of membrane proteins

... experimental techniques and theoretical structure prediction methods to produce simple structural models for some 600 membrane proteins from Escherichia coli. They have also identified those membrane proteins that the bacterium can manufacture in large amounts, and those that it has difficulties to make. This ...

Biomarkers isolated from saliva successfully predict oral and breast cancer

...volve a larger sample of cancer patients to refine prediction models, but also will include studies involving precancers and other difficult to detect cancers such as ovarian and pancreatic cancers. "In my mind the biggest hurdle stems from the fact that salivary nucleic acids or protein markers might be influ...

Program finds lost genes in nematode genome

... point "We've crossed the tipping point with gene prediction where it's becoming clear that machines can beat h... Cryptococcus neoformans. Brent's approach to gene prediction stands traditional genome annotation on its head because it starts with a computer analysis of the g...

Bioinformatics reveals new gene regulation system

...raits of transcription factors. To strengthen the prediction that these proteins were the transcription factors that bind the NrdR-box, the team used another comparative genomic tool called positional clustering. Positional clustering takes advantage of the fact that functionally related gene sequences (such a...

'Shifty-eyed' Monkeys Offer Window Into Brain's Social Reflexes

...e movements of the subjects. Explained Platt, 'Our prediction was that if seeing a monkey looking in one direction or another actually changes where you're paying attention, then you should shift your gaze faster if the box appears in the direction in which that monkey face was looking and slower in the other d...

New imaging technology shown to detect pancreatic inflammation in type 1 diabetes

...ing autoimmune diabetes, but most of all for early prediction of response to therapy, which might be very useful for reducing the time and cost of clinical trials. "Because the results in mice looked so good, and because our MGH colleagues have already successfully used essentially the same drug on many patient...

Modification of program enables prediction of gene transcription

A modification to an "ace" gene prediction program by computer scientists at Washington Unive...st exon of the gene. The modification to the gene prediction software TWINSCAN is called N-SCAN. Michael Brent, Ph.D. professor of computer science at Washington...

New technique may speed DNA analysis

..., say, the early diagnosis of liver cancer, or the prediction of the chances that a couple will produce a child with a genetic disease. Frequent, widespread use of these devices is hindered by the fact that producing them is a painstaking process that involves at least 400 printing steps and costs approximatel...

New technique helps identify multiple DNA regulatory sites

..., say, the early diagnosis of liver cancer, or the prediction of the chances that a couple will produce a child with a genetic disease. Frequent, widespread use of these devices is hindered by the fact that producing them is a painstaking process that involves at least 400 printing steps and costs approximatel...

Gaining ground in the race against antibiotic resistance

...esign, Vila said, by giving drug makers a reliable prediction of what the next generation of enzymes will look like. "Since we were able to reproduce the natural evolution in the test tube, you could generate a more efficient lactamase to use as a target, so that your inhibitor would be one step ahead." This...

Computers close in on protein structure prediction

..."We achieved almost atomic resolution in structure prediction for about one-third of our benchmark set of small ...t energy shape is selected as the prediction. The prediction process happens in two steps, Bradley said. The first stage uses an approximate model which allows r...

Neurotransmitters signal aggressive cancer, offer potential for early diagnosis

...ated software that supplied the researchers with a prediction about which metabolic reactions were revved up in the tumors and which were slowed down. The last piece of the puzzle was supplied by a highly sensitive instrument, called a mass spectrometer, that measured the products of cellular metabolism. The ma...

Researchers use brain scans to predict behavior

...alien and unpredictable. Other areas involved in prediction included regions in the visual cortex involved in the analysis of the motion display and regions involved in the control of visual attention. "These activations may reflect the degree to which subjects variably directed attention on each trial to t...

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