Rensselaer researchers develop approach that predicts protein separation behavior
...eviously developed by Breneman's group for rapidly predicting the efficacy and side effects of small drug-like m...parameters then replicated experimental results by predicting the actual separation profile of proteins in chromatographic columns. Chromatography techniques are ...... the teams were able to develop a set of rules for predicting the location of binding site combinations based on limited binding site and gene expression data. "We found that the same transcription factors, in slightly different combinations, could be responsible for the regulation of different genes," said To...U-M researchers identify new blood test for prostate cancer
...n says. The results proved to be more reliable at predicting cancer than prostate specific antigen, which is a single biomarker. PSA testing results in a false positive around 80 percent of the time, leading to unnecessary prostate biopsies. The normal range for the PSA test is less than 4.0 nanograms per mill...Modification of program enables prediction of gene transcription
... the past two years, TWINSCAN has been finding and predicting genes in numerous genomes that other gene predicti...otential to scan three or more ?strengthens it for predicting both coding and non-coding DNA. "Like any multiple choice question, if you can learn something abou...Traditional models underestimate extinction rates
...derestimate extinction rates. Standard models for predicting extinction assume that population growth and decline are governed by random, or stochastic, variables. But few scientists have actually tested the accuracy of these models with empirical data. To do this, Drake first manipulated the available food so...Computers close in on protein structure prediction
...arch is exciting is that we're showing progress in predicting the structure from the sequence. It's not that the problem is solved, but that there is hope." Proteins are biological machines, and scientists need to determine their structures to understand how the proteins work. Now, scientists determine structu...Rutgers to lead $52.7 million protein research program
...e structures, in turn, have provided templates for predicting models of over 40,000 protein structures using methods of structural bioinformatics. Other NIGMS pilot program centers brought the total to about 1,500 structures which can be used to model thousands of other proteins in each of the families they rep...Elusive salamanders have role in developing new sampling models
...odels, and we should be able to do a better job of predicting the type and location of suitable habitats plus mi...y the relative importance of different factors for predicting the presence of salamanders. This process will provide valuable information for the management of fl...Eleven gene 'signature' reliably predicts cancer prognosis
... analysis identifies a death from cancer signature predicting therapy failure in patients with multiple types of cancer ...Method slashes quantum dot costs by 80 percent
...eloped by Mantzaris, the team now has a method for predicting the particle size and growth behavior of quantum dots based on only three physical properties of a given solvent: viscosity, surface free energy and solubility of bulk cadmium selenide powder. ...The right drug at the right time
...eloped by Mantzaris, the team now has a method for predicting the particle size and growth behavior of quantum dots based on only three physical properties of a given solvent: viscosity, surface free energy and solubility of bulk cadmium selenide powder. ......he current study. "We've made a lot of progress in predicting how globular domains interact with each other. But...ein called a linear motif. Finding such motifs and predicting where they fit in is like looking for needles in haystacks." Or like looking at a line of automobil...Minimal genome should be twice the size, study shows
...ts size." The researchers have developed a way of predicting bacterial genome content using two bacteria that have evolved from E.coli. Buchnera and Wigglesworthia live inside insects in a symbiotic relationship where they provide essential molecules for their hosts in return for essential basic foods. Sinc......agnetic resonance imaging- (MRI-) based method for predicting possible problems. The findings of their studies on animals, which appeared in the journal Cancer Research, may, in the future, influence treatment regimes for millions of cancer patients. Intravenous infusions rely on the bloodstream to carry dru...Environmental metagenomics diagnosing extreme environments, tapping opportunities for clean energy
...oring platforms, and ecosystem forecast models for predicting the impacts of climate change. For a full session description, see: http://php.aaas.org/meetings/MPE_01.php?detail=974 "Environmental systems are extremely complex, harboring numerous diverse species coexisting in a single niche," says Rubin. "The...High-tech tags on marine animals yield valuable data for biologists and oceanographers
...apabilities of the model, Costa said. "It's like predicting the weather. To get accurate predictions, the weather models have to be constantly updated with new data from weather stations all over the country," he said. The researchers are also gaining new insights into the lives of California sea lions, said...Researchers use dirt to stay one step ahead of antibiotic resistance
...resistance happens in bacteria that infect people, predicting future clinical problems, and testing new antibiotics. Antibiotic resistance has become an increasing public health concern because the organisms that cause infections in humans and animals are becoming less receptive to the healing aspect of antibi...Absence of critical protein linked to infertility
...in's presence could become a vital gene marker for predicting uterine readiness for pregnancy. "The success rate for the practice of in vitro fertilization currently is, on average, about 25 percent," she said. "The major problem is that the conditions occurring when the embryo is transferred often are not th...Extinctions linked to climate change
... found in parts of the southern United States. And predicting how climate change will favor a certain pathogen or disease transmission is extremely difficult. "We should expect the unexpected," Blaustein and Andy Dobson of Princeton University wrote in their report. "Terms such as 'enigmatic decline' and 'path......esses in three connected oceans and are crucial to predicting the consequences of climate change on the whales." Southern right whales have been internationally protected since 1935. Their populations are showing signs of recovery, however, sea surface temperatures in parts of the Southern Ocean have increased...