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Tag: "predicted" at biology news

A new mechanism of regulating RNA degradation

... new function for Staufen1 that couldn't have been predicted from the studies in flies, even though a similar function may occur in flies." The team discovered that Staufen1 doesn't interact with other components of the NMD complex ?and altering the amount of Staufen1 in the cell didn't change NMD function. T...

FDA Approves Human Hookworm Vaccine for Phase I Safety Trials

... new function for Staufen1 that couldn't have been predicted from the studies in flies, even though a similar function may occur in flies." The team discovered that Staufen1 doesn't interact with other components of the NMD complex ?and altering the amount of Staufen1 in the cell didn't change NMD function. T...

Anti-bacterial additive widespread in U.S. waterways

...ironmentaloccurrence of triclosan, the researchers predicted triclocarbanconcentrations for 85 U.S. streams. Th...ity of the analysis, the researchers comparedtheir predicted nationwide levels of contamination to experimentallymeasured concentrations in the Greater Baltimore...

New imaging method gives early indication if brain cancer therapy is effective, U-M study shows

...nd that any change in the functional diffusion map predicted 10 weeks before traditional techniques if the tumo...patients, a change in the diffusion MRI accurately predicted the tumor's response. Researchers plan to test the technique with breast cancer and head and neck ca...

Examination of internal 'wiring' of yeast, worm, and fly reveals conserved circuits

...s, such as yeast, which don't have nerves. Ideker predicted that protein-interaction studies will soon become indispensable tools for biologists seeking a better understanding of all cellular functions. He said that just as a species evolved new proteins to give it a selective advantage, it also could have ev...

Children's taste sensitivity and food choices influenced by taste gene

...-sensitive allele (P) on the TAS2R38 receptor gene predicted sensitivity to the bitter taste of PROP in both ch...more research." The bitter receptor genotype also predicted children's sweet preference, along with their preference for sweet-tasting beverages and foods. Chil...

Genrate: a generative model that finds and scores new genes and exons in genomic microarray data

...ade some progress in using microarrays to validate predicted exons in genome sequence and find new gene structures. However, current methods rely on separately making threshold-based decisions on intensity of expression, similarity of expression profiles, and arrangements of exons in the genome. We have taken...

Nanoscale Diagnostic Sets Sights on Alzheimer's

...ns when ADDLs attack key synapses in the brain. We predicted some of these ADDLs would leak into the cerebrospinal fluid, but until now we couldn't detect them. Thanks to the extraordinary sensitivity of the BCA it's been possible to validate the prediction, and maybe even set the stage for creating the first ...

Institute for Systems Biology Symposium Addresses Need for Better Computational Tools

... World Community Grid in November 2004 has already predicted 50,000 protein structures. "This project showcase...urrent computational power at ISB. We have already predicted 50,000 protein structures and are well on our way to reaching the goal of between 100,000 - 150,000 ...

Gray wolves maintain the food chain in winter

...ield researchers can measure the magnitude of this predicted buffer effect. The models described here can guide their efforts and help species adjust to major environmental shifts like climate change. Crucially, Wilmers and Getz's study shows that a robust food chain - including this still embattled top predat...

Computational Method Speeds Mapping of Cell Signaling Networks

...A for transfer of the signal. The team's analysis predicted all but three of 18 well-studied T-cell network relationships. Although the work was largely a "proof of principle" report designed to demonstrate the usefulness of their method, their studies also identified a previously unknown T-cell signaling int...

Revolutionary nanotechnology illuminates brain cells at work

...d ybeJ from the common bacterium E. coli. We first predicted the structure of this protein, and then placed the two fluorophores at specific positions on the binding protein," commented co-author Loren Looger. "After fusion to the fluorescent proteins, we placed the sensor on the surface of rat hippocampal cel...

Brain Scans Reveal How Gene May Boost Schizophrenia Risk

... that increased activity in the front of the brain predicted increases in the neurotransmitter dopamine in the middle of the brain in subjects with the suspected schizophrenia-related version of the gene. Yet, the opposite relationship held for subjects with the other of two common versions of the gene. "A ti...

Biomarkers isolated from saliva successfully predict oral and breast cancer

...orted that genetic "biomarkers" isolated in saliva predicted oral squamous cell carcinoma in about nine out of 10 cases. A recent study by this group, published in Clinical Cancer Research, disclosed similar predictive powers for head and neck cancers. "These results indicate that such biomarkers found in sa...

Oceans more vulnerable to agricultural runoff than previously thought, study finds

...ary source of nitrogen pollution, and their use is predicted to double or triple over the next 50 years." ...

Measuring Enzymes At End Of Cancer Pathway Predicts Outcome Of Tarceva, Taxol

...itoring of two isotypes of CDK activity accurately predicted which tumors would respond to Taxol in the experiments with human breast cancer cell lines and tumor tissues of human xenograft model. "This provides solid preclinical evidence that we can use toward development of a novel device that can measure CD...

Signs of aging: Scientists evaluate genes associated with longevity

...ose obtained from controls at different ages. They predicted that genes exhibiting coordinated up- or down-regulation from early to late adulthood would be those most critical to the vital biological process of aging. In addition, they reasoned that some of the genes that were differentially expressed between ...

Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics

...ese connected molecules have failed to exhibit the predicted electrical properties when tested without a conducting solution. Physicists attempting these measurements avoided using electrolyte solutions because the applied current would leak into the surrounding solution. Lindsay and his team solved this probl...

Venom doc tracks down snake bioweapons

...rmal expression pattern of that protein family, he predicted from which tissue type each toxin protein had been derived. Despite the differences in tissue origin, Fry observed that all toxins were derived from protein families with secretory function. This means that the proteins were produced in a specific t...

Mice brains shrink during winter, impairing some learning and memory

...ally related memory and learning performance. "We predicted that when you reduce the size of the hippocampus, it would have an impact on learning, and that's what we found," Nelson said. The shrinking of the brain corresponds to a season when the mice may have less need for spatial memory, Nelson said. "The...

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