Inflammation and drugs to control this activity studied in a variety of tumors sites
...ould use molecular tools, such as COX-2 levels, to predict who among the group of women with atypia would develop breast cancer and develop ways to separate groups of women into high risk and normal risk. The COX-2, or cyclooxygenase-2, enzyme is produced by the body when there is inflammation and is also pr...AIDS-related cognitive impairment exists in two separate forms
...n the best outcome. Currently, physicians cannot predict which patients with prostate cancer should receive...No. 5723 Oncologists say it is very difficult to predict which patients with colorectal cancer will be cured by surgery alone - the single treatment most pat...Markers of gene, protein, or micro-RNA activity predict outcome in prostate and colorectal cancers
...n the best outcome. Currently, physicians cannot predict which patients with prostate cancer should receive...No. 5723 Oncologists say it is very difficult to predict which patients with colorectal cancer will be cured by surgery alone - the single treatment most pat...Nanopore method could revolutionize genome sequencing
... of atoms and electrons that behave in ways we can predict and manipulate," said Di Ventra. ......reviously developed by Riesenhuber and his team to predict how different neurons would react during the recognition of non-face objects. They then showed that this simple model, even though not developed for face recognition, could quantitatively account for the inversion effect and make predictions about ho...Scientists discover new genetic subtypes of common blood cancer
...uthor of the paper, said the findings "allow us to predict how patients will respond to current treatments ba...se aberrations in an individual patient might help predict how aggressive the disease would be. For this deeper analysis, the researchers created an algorithm...BioMed Central launches Biology Direct
...gainst issues that had actually not been raised ?I predict that a fair percentage of the manuscripts published in Biology Direct will later prove to have an important impact in their own right?The end result of this refereeing process is, I hope, a much better manuscript." ...Poison dart frog mimics gain when birds learn to stay away
... into account, says Cummings, you can successfully predict a specific direction of mimicry in evolution. In studying the toxicity and abundance of all three species, Darst found that the harmless frog mimics either toxic frog where they live separately. In the north, the mimic looks like the less toxic spec...Biologists develop genome-wide map of miRNA-mRNA interactions
...rnia, Berkeley have used computational analyses to predict a genome-wide map of microRNA (miRNA) targets in the animal model organism, Caenorhabditis elegans (C. elegans). MicroRNAs bind to messenger RNA (mRNA) in a specific section, called 3'UTR, and are known to regulate them. Parts of the predicted map we...Scientists develop malaria forecasting tool to predict disease risk
A new tool to predict epidemics of malaria up to five months in advance ... used forthcoming season forecasts for rainfall to predict unusual changes in the seasonal pattern of disease in Botswana. The team based their study on Botsw...Therapeutic prospects beyond Vioxx
... a harmful one called thromboxane. This led him to predict that drugs in this class might confer a cardiovascular risk before either reached the US market. In the present studies, the investigators used multiple genetically manipulated mice ?including mice that mimicked the impact of either COX-2 inhibitor...Exotic crab poised for widespread UK invasion
...experienced a major outbreak. The study authors predict that the mitten crab - so called because its claws are coated with small clumps of dark brown fur, or mittens - has the potential to establish itself in all major UK estuaries in several years time. Mitten crabs are unwelcome because they prey on p...New test to detect rare proteins in blood
... extent of disease. Post-treatment Her2/neu levels predict disease-specific survival. A more sensitive assay could more accurately allow treatment of humans with breast cancer and allow treatment more quickly if the tumor reoccurs. The researchers collected blood samples from healthy women and breast cancer...How can we protect patients with weakened immune systems from influenza?
... cells that recognize and fight influenza may help predict whether a patient will produce protective antibodies after vaccination. Producing those antibodies is the job of B cells. "We hope to be able to use a simple blood test to help determine which immunocompromised patients will benefit from an influenza...St. Jude projects 90 percent cure rate for ALL
...ample were leukemic. "MRD measurements help us to predict the ultimate response of each patient to treatment," Pui said. "That information helps us to determine how intensive the rest of the therapy should be. Our goal is the complete eradication of leukemic cells with the least toxicity to the children." ...Two NIH initiatives launch intensive efforts to find roots of common diseases
...tionize the practice of medicine by allowing us to predict disease, develop more precise therapies and, ultimately, pre-empt the development of disease in the first place."Public-Private Partnership At the same time, a public-private partnership between NIH, FNIH, which is a non-profit foundation establishe...Access to antiretrovirals unlikely to reduce HIV infection rates
...test this, Baggaley and colleagues used a model to predict and compare the impacts of alternative strategies of increasing ART access in resource-poor countries. Some of the strategies included the provision of diagnostic laboratories that could routinely measure CD4 counts and viral loads of HIV-infected in...Parts of the Caribbean and Central America are likely to have less summer rain
...t a dramatic one, Neelin said. The computer models predict that will be a continuing trend. "We can't exclude that the precipitation decrease over the last 50 years is part of a natural cycle, unrelated to global warming," Neelin said. "It is plausible that the decrease is due to global warming, but there i...UCLA scientists uncover mechanism of response to targeted therapy
...chanism behind the response, they would be able to predict which patients would respond and personalize their treatment accordingly. Extrapolating from the clinical responses, Jonsson Cancer Center scientists uncovered the cascade of molecular events by which the cancer cells in a subset of patients became ...For some young fish, early gene expression is a clear harbinger of fated lifestyle
...ssion levels of relevant genes, it was possible to predict the future lifestyle of fish at the juvenile stage. ...