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Tag: "predict" at biology news

Yale scientists decipher 'wiring pattern' of cell signaling networks

...ogical functions of cells. Although scientists can predict from the DNA what proteins are in the proteome of an organism, this study opens the door to seeing how they are coordinated to work together. "This insight into the regulation and integration of biological networks has broad applications for basic s...

Tropical Atlantic cooling and African deforestation correlate to drought, report scientists

...perature and vegetation cover on land. "We can't predict how, but it is clear that this human-induced change will change the terrestrial and ocean system," he says. He notes that droughts in this region are currently occurring more frequently than in the past few thousand years, although the frequency of t...

Technique offers new view of dynamic biological landscape

...ne participates in could also enable clinicians to predict the variability of effects of a drug among different people. Understanding such interactions could also give pharmaceutical researchers clues to the magnitude of possible side effects of drugs under development. The development of combination drug ...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

...ewly identified gene expression profile could help predict how patients with advanced ovarian cancer will res... Chemotherapy Response Profile (CRP), was found to predict which patients would experience a complete response to chemotherapy, as defined by the absence of di...

New technique helps researchers determine amino-acid charge

...ve previously relied on theoretical estimations to predict protonation states -- whether an amino acid is charged or not. Appropriate experimental benchmarks also had been lacking. All cells have membrane proteins that form channels to allow water and/or ions to pass through. Malfunctions have been linked t...

How E. coli bacterium generates simplicity from complexity

...but Palsson noted that several theoretical studies predict that even eukaryotic cells will exhibit a relatively small number of functional states. "When we uncover the regulatory networks in eukaryotes, including human, we will most likely be able to use computer simulations to uncover the different possible...

Gene variation affects tamoxifen's benefit for breast cancer

...ess severe, suggesting that this side effect could predict the gene variation. Further studies are needed, but researchers hope one day this finding may lead to a genetic test that could help doctors determine which women are most likely to benefit from tamoxifen. This type of test is not currently offered ...

Scientist uses form to explain function of key building blocks of life

...ds in a protein. The scientists were then able to predict the function of different versions of the protein ... like to be able to start with a gene sequence and predict the structure of a protein and its function. In this case, given an NMR pattern, we can tell you ho...

Microarray technology for tailoring breast cancer therapy

... identified a group of64 genes that can be used to predict a patient's response in the five years after adjuv...s express these genes could potentially be used to predict which patients would not benefit from adjuvant therapy, and avoid patients being given therapies wit...

Novel enzyme offers new look at gene regulation

...ins share little else in common. Database searches predict more than 100 total proteins found in organisms as diverse as bacteria and man contain the JmjC domain. This suggests that many other proteins may act similarly to methyl groups from histones or other proteins. The implications of the new findings a...

Evolutionary conservation of a mechanism of longevity from worms to mammals

...is gene is active. Because these findings would predict that reduced expression of the mclk1 gene would result in longevity, the authors compared the lifespan of mice heterozygous for mclk1 with their wild-type counterparts. A predicted, mclk1+/- mice displayed a substantial increase in lifespan in three...

Free-energy theory borne out in large-scale protein folding

...d theory and experiment for the first time to both predict theoretically and verify experimentally the protein-folding dynamics of a large, complex protein. The interdisciplinary research appears this week in two back-to-back papers in the Proceedings of the National Academy of Sciences. "Researchers have ...

Missing fossil link 'Dallasaurus' found

...r the pieces of the mosasaur puzzle. In fact, they predict the legacy of Turner's discovery will live on. His contribution was honored by naming the species, "turneri," after his last name. "Not all major discoveries are made by highly trained paleontologists," notes Dallas Natural History Museum Curator Fio...

Scientists map one of biology's critical light-sensing structures

...d, Vierstra says. "This memory allows the plant to predict where the light will come from each day and measure the length of daylight so that they flower in the correct season." By deducing the architecture of the phytochrome protein, according to Vierstra and Forest, it may be possible to engineer and intro...

Scientists pinpoint inflammation gene

...BR scientists to sift through this information and predict which of these genetic variants was most likely to have a direct effect on inflammation. For this effort, they relied on 1,500 parallel processors in the foundation's SBC Genomics Computing Center. An unparalleled resource for genetic analysis, the ...

Underlying cause of massive pinyon pine die-off revealed

...rs said the team's next step is developing ways to predict how bad a drought must be to cause such large-scale die-offs. Breshears, Cobb and Rich's coauthors include Kevin P. Price and Jude H. Kastens of the University of Kansas in Lawrence; Craig D. Allen of the U. S. Geological Survey in Los Alamos, N.M.;...

Marine conservation organizations team up to conduct Indonesia coral reefs assessment

...t to determine the status of the reefs in order to predict future food availability from the sea in this area," said Reef Check Director Gregor Hodgson, Ph.D., who will be coordinating the two-week expedition. "This disaster presents a great opportunity to reinforce the concepts of marine management in Indon...

Science's Breakthrough of the Year: Watching evolution in action

...tion of last century's deadly bird flu may help us predict and cope with the current bird flu threat. Other studies showed how small changes in DNA can trigger dramatic evolutionary events. Researchers found that a single genetic change can be all it takes to turn one species into many, as in the case of th...

Storing carbon to combat global warming may cause other environmental problems, study suggests

...laces tend to be relatively low rainfall areas. We predict we will see a decrease in stream flow particularly... as water vapor emanating through leaf pores. To predict whether this increased moisture might boost rainfall to counter tree water withdrawals, co-authors B...

Study Unlocks Insects?Secret for Love in the Dark

...g is still mysterious, so doctors can't accurately predict how each injured patient will fare. To address t...s knowledge eventually will help physicians better predict patient outcomes and tailor treatments accordingly," said Jeremy M. Berg, Ph.D., director of the Nat...

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