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Tag: "precise" at biology news

Advanced genomics and proteomics improve the diagnosis and treatment of a deadly lung disease

...o carefully measures and snips strands of RNA into precise increments. When Dicer cleaves large strands of RN...ws how the enzyme recognizes RNA and snips it into precise increments. "The fact that it makes these specific sized RNAs is important to the process," Doudna ...

How the octopus forms an elbow

...-jointed vertebrate limb when the octopus performs precise point-to-point movements. Researchers have now ill...the optimal solution to the challenge of achieving precise point-to-point movements by a limb. ...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...ne by allowing us to predict disease, develop more precise therapies and, ultimately, pre-empt the developmen...tain health or lead to disease. Without these more precise measures of exposure, it will be very difficult to figure out why certain people develop disease and...

Intensive statin therapy may partially reverse plaque build-up in arteries

...suvastatin (brand name Crestor®). IVUS provides a precise and reproducible method for determining the change in plaque, or atheroma, burden during treatment. Atherosclerosis progression was assessed at baseline and after at 24 months of treatment. "Previous similar studies with statins have shown slowing ...

New test to detect rare proteins in blood

...r multiple diseases at the same time and produce a precise accounting of whether disease-causing molecules are present at an early time when disease can be readily treated," adds Greene. Greene also noted that the FACTT technology represents the further evolution of an earlier approach that was developed i...

Creation of antibiotic in test tube holds promise for better antibiotics

...ids and provide sturdy protease-resistant bonds at precise locations. They account for nisin's robust resistance capability. It was theorized that one enzyme makes all five rings despite their very different sizes, but how it did so was like the mystery of a magic show, van der Donk said. Nisin is one of nu...

Berkeley researchers lay groundwork for cell version of DNA chip

...ted cells ill-suited for applications that require precise patterns of multiple cell types. The authors behind the Angewandte Chemie paper have solved the problem with the creation of a highly selective cell adhesion system that uses single-strands of synthetic DNA to fasten the cells to a surface. This en...

UF scientists trace origin of shark's electric sense

...tic field for navigation, enabling them to swim in precise paths across large expanses of featureless ocean, Cohn said. "If you think of this in the big picture of evolution of sensory systems, such as olfaction, hearing, vision and touch, this shows sharks took a pre-existing genetic program and used it to...

FDA approves first medical device using rutgers biomaterial

... improved handling characteristics that facilitate precise placement during the surgical repair and leave less implant material following the resorption of the coating. Hernias occur when musculature fails and one part of the body protrudes through the resulting gap or opening into another part of the body...

Engineered heart tissue offers insights into irregular heartbeats, defibrillator failure

...ells into culture dishes on which they had stamped precise patterns of proteins known to support heart tissue growth. The proteins caused the cells to orient themselves, interconnect and grow in a manner that mimics normal heart tissue, Bursac explained. The team then induced electrical activity in these en...

Common molecular 'signature' identified in solid tumors

...t I am convinced that this field will give us more precise and less toxic ways of dealing with cancer than we have today ?even considering some of our new, molecularly-targeted therapies." Support from the research came from the National Cancer Institute, the Italian Ministry of Public Health, the Italian Mi...

Weighting cancer drugs to make them hit tumors harder

...of the drug. If you balance the two factors with a precise weight, you get optimal drug concentration." Chil...r weight is not a new concept, but determining the precise weight to achieve optimal drug concentration has proved difficult, he said. Chilkoti and his colleag...

Johns Hopkins lab scientists tame overactive CF protein

...try. Until now, researchers had not identified the precise search-and-destroy proteins that ERAD deploys to seek out the mutant CFTR. "We were able to confirm that to get rid of the defective CFTR protein, cells deploy VCP/p97 protein, which latches onto the damaged CFTR and sends it to the proteasome for d...

DOE JGI releases IMG 1.5 with curated archaeal genomes

...enges in genomics remains the determination of the precise location of genes from DNA sequence information. DOE JGI has embarked on curating the gene models of microbial genomes culled from public sources. Towards this goal, IMG 1.5 now contains 22 archaeal genomes with curated gene models and detailed docu...

New MRI technique quickly builds 3-D images of knees

...amped magnetic resonance scanner, yet deliver more precise 3-D images of their bodies. Developed at the University of Wisconsin-Madison, the faster technique will enable clinics to image more patients - particularly the burgeoning group of older adults with osteoarthritis-related knee problems - and can he...

Radiation-armed robot rapidly destroys human lung tumors

...a radiation delivery system that uses an accurate, precise robotic arm to aim highly focused x-ray beams at the site of a tumor. Currently there are 76 active CyberKnife sites worldwide (with 45 in the US), and an additional 62 scheduled to be installed globally. Recently, the Pittsburgh researchers upgra...

It's all in the genes

...hrough DNA fingerprinting, the scientists know the precise genetic makeup of each tree. In one experiment, Whitham's group worked with the Bureau of Reclamation to plant about 10,000 trees at the Cibola National Wildlife Refuge along the lower Colorado River, about 20 miles south of Blythe, Calif., to exam...

UF scientists restore sight to chickens with blinding disease

... at all of them. It was so exciting." Later, more precise tests showed that of the seven treated chickens, five displayed near-normal visual behavior. Measurement of electrical activity in the retinas of the same five animals showed they responded to light. In comparison, tests on three untreated chickens s...

Bubbles go high-tech to fight tumors

...ite. Gas bubbles, on the other hand, allow very precise delivery because their formation can be controlled and directed from the outside, by a focused high intensity ultrasound. This envisioned technique is actually a two-step process, Bull said. First, a stream of encapsulated superheated perfluorocarb...

The molecular mechanism of a diabetes vaccine revealed

...al trials in Europe and the United States, but its precise mechanism has until now been unknown. "When translating these findings into a practical vaccine, we knew enough about the mechanism to understand that this protein is able to cause a decrease in the immune response, but how it actually works eluded ...

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