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Tag: "precise" at biology news

Genetic defects give the immune system the green light to attack the pancreas

...osomal regions involved and can now zero in on the precise genes,?said Diane Mathis, Ph.D., the study’s princ...regions are known, the researchers are seeking the precise genes involved. “Once these genes are identified, we will be better able to define the biologic path...

Protein helps regulate the genes of embryonic stem cells

...the unit of genetic information." Depending on the precise nature of the histone modification, any given gene associated with modified histones is marked to be turned on or off. In the study, eed is the first protein shown to be required for the addition of a single methyl group to histone H3, said Montgome...

Of mice and men's (and women's) contraceptives

...entiation. As cells become mature sperm, there's a precise order of synthesis of many essential proteins needed to create functional gametes. We think the absence of the MSY2 protein causes problems in the timing of sperm or egg development. We're working hard on understanding this mechanism." A similar hum...

Doing a spin with DNA

... topisomerase between 'cutting' and 'gluing'. The precise mechanism of topoisomerase IB is also important for cancer research. Drugs which inhibit the functioning of topoisomerase IB are already in clinical use, but can possibly be improved using the knowledge from this study. ...

Gene keeps neural cells on correct developmental path

...in differentiating neurons probably orchestrates a precise sequence of genes sensitive to different levels of REST, Mandel speculates. REST has been a difficult gene to study. Using knockout technology -- a popular technique for determining gene function -- does not work for REST because mice lacking the ge...

Software Tool for Converting Scientific Text into a Database of Functional Relationships

...ed dictionaries of protein and chemical names, and precise text parsing and pattern matching algorithms specifically developed for biological text analysis. It extracts functional relationships between proteins, cell processes, and small molecules, recognizes types of regulatory mechanisms involved and the e...

Ariadne Genomics Announces the Release of PathwayStudio?Central, Client-Server Software for Biological Pathway Analysis

...ed dictionaries of protein and chemical names, and precise text parsing and pattern matching algorithms specifically developed for biological text analysis. “PathwayStudio?Central helps scientists to keep current with literature using embedded MedScan information extraction tool that can “read?scientific te...

Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage

...h as skin and the linings of the lung. While their precise role remains poorly understood, they perform vital...ponses and halting unwanted ones. "Although their precise function is still unclear, delta-gamma T cells seem to form the first line of response against exter...

Scientists analyze chromosomes 2 and 4

...pair stretch of DNA sequence that likely marks the precise location of the inactived centromere. That tract is characterized by a type of DNA duplication, known as alpha satellite repeats, that is a hallmark of centromeres. In addition, the tract is flanked by an unusual abundance of another type of DNA dupl...

Penn Researchers Use Robotic Surgery

...led to eliminate any tremors and allow for steady, precise movements. "When operating with the daVinci System, the optics and fluidity of instrument movement are just amazing," adds Hockstein. "It has the potential to add great precision to our surgical treatment of a variety of diseases of the head and neck...

Two new retroviruses—transmitted from animals—identified

...led to eliminate any tremors and allow for steady, precise movements. "When operating with the daVinci System, the optics and fluidity of instrument movement are just amazing," adds Hockstein. "It has the potential to add great precision to our surgical treatment of a variety of diseases of the head and neck...

Computational Tool Predicts How Drugs Work In Cells, Advancing Efforts To Design Better Medicines

...l ally ?a mathematical algorithm that predicts the precise effects a given compound will have on a cell’s mol... process of designing therapeutic drugs is neither precise nor efficient. The BU research team sought to bring precision and efficiency to this discovery proc...

How exactly does the brain control breathing?

...sue highly debated by Guyenet and Richerson is the precise location and cell types involved. Guyenet proposes that these nerve cells are located in a ventral area of the brainstem (the retrofacial region) and loaded with a transmitter substance called glutamate. Their close proximity to the ventral surface o...

Mosaic mouse technique offers a powerful new tool to study diseases and genetics

...the tumor grow." Luo points out that MADM is more precise than the widely used "knockout mouse" technique, in which a gene of interest is removed ("knocked out") of every cell in the animal's body. The knockout method can have unwanted, deleterious consequences for the mouse and the experiment, Luo adds, wh...

Mapping neuron connections in the brain

...ulations or tedious experimental methods requiring precise three-dimensional reconstructions of neuron arbors, tremendously branched structures formed by neurons. Part of the difficulty in mapping lies in the complex structure of arbors. Amirikian has improved on past methods by developing a theoretical fra...

Poaching, logging, and outbreaks of Ebola threaten central African gorillas and chimpanzees

...sible. While the experts were unable to establish precise population figures for the gorillas and chimpanzees, they determined that recent Ebola outbreaks, bushmeat hunting and logging have almost wiped out some populations. The action plan noted that apes reproduce slowly, with limited capacity to recover ...

New Vaccine To Be Used For First Time In Polio Outbreak Response

... genetic investigation is ongoing to determine the precise origin of the outbreak. Experts fear that the number of cases will rise in the immediate future. Teams of WHO and Ministry of Health epidemiologists and paediatricians remain on the ground, to investigate and control the outbreak and to intensify th...

Malaria killing a million a year

...ce 2001. "Current methods do not allow for a more precise estimate, given that malaria is most often not diagnosed with certainty, as well as the scarcity of reliable data from the communities where it occurs," WHO and UNICEF say. The Millennium Development Goals (MDGs), a set of targets agreed at a UN sum...

Breakthrough: Scientists create world's tiniest organic particles

...this, no one else has fused the highly uniform and precise methods for fabricating transistors with the organic nanoparticle world," said Bruce Boucher, president of Liquidia. "It is truly a revolutionary discovery." ...

Study: Harmless virus kills some cancers

...gene therapy. Future studies will investigate the precise mechanisms through which AAV2 causes cancer cell death, and how the virus might be enhanced to more aggressively target and kill cancers. A provisional patent application for this work was recently submitted. ...

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