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Tag: "potent" at biology news

NASA study: Alaskan fires affected Houston air quality in 2004

...pollution generated in the Houston area provided a potent mix for increasing local ozone concentrations, he said. Morris said it's likely that such pollution episodes will continue. Understanding the transport and transformation of gases and aerosols over long distances is needed for improved understanding...

New biochip helps study living cells, may speed drug development

...arget sodium-channels. In nature, some of the most potent venoms and toxins work by blocking these channels, including the venom of certain snakes and strychnine. Porterfield's chip is technically classified as a "cell electrophysiology lab-on-a-chip." The device is further described in an article in th...

Circadian gene helps the brain predict mealtime

...lished by Cell Press. A daily scheduled meal is a potent time-giving cue that can reset the physiological timing of most organs, including the liver. In terms of animal behavior, a daily scheduled meal elicits anticipatory bouts of locomotor activity and changes in body temperature. These food-anticipatory...

Cloning techniques produce FDA-approved antibiotic

...fomycin in a cost-effective manner and create more potent derivatives of it." Previously, four essential genes and a portion of fosfomycin's biosynthetic pathway had been proposed, but researchers were unable to produce fosfomycin in a non-native host. Zhao's findings indicate that the presence of additio...

Sandia research to focus on early detection of harmful algal blooms

...ear the surface of the water, however, can produce potent neurotoxins that are then transferred through the food chain, accumulating in zooplankton and shellfish, eventually harming or even killing marine mammals and humans that consume tainted shellfish. Sandia to focus on early-warning detection method...

AIDS study challenges conventional treatment guidelines for HIV patients

... credited with saving millions of lives. However, potent side effects and issues of drug resistance, often cause doctors and patients to defer starting the medications, until it becomes medically necessary. In addition to the clinical ramifications, the findings suggest that HIV-associated CD4 depletio...

Scientist works to improve treatment for brain tumors

...m is to identify the drug design that has the most potent anti-tumor efficacy," he said. Debinski will also explore how cancer cells' lack of oxygen affects the treatment. Hypoxia, a lack of oxygen in tissues that causes cell stress, is a characteristic common to all solid tumors and is known to interfere ...

Mayo Clinic Cancer Center: Harnessing the measles virus to attack cancer

...administration of higher and potentially even more potent viral doses." The glioblastoma multiforme study, which opened today, is designed to test the safety of the virus for the treatment of gliomas and enable biological monitoring of anti-tumor activity. "The measles virus we are using in the gliobl...

Study defines effective microbicide design for HIV/AIDS prevention

...said. "Our findings demonstrate the need to pair potent active ingredients with well-engineered delivery vehicles, and they highlight the importance of the dosage form -- especially its ability to restrict viral diffusion and remain in place -- in microbicide effectiveness," Katz added. More than 20 mic...

Ozone recovering, but unlikely to stabilize at pre-1980 levels, says study

...to reach light or strengthen stems. Exploiting its potent growth-promoting properties could increase crop yields or enable growers to make plants more resistant to drought, pathogens, and cold weather. Unfortunately, synthesizing brassinosteroids in the lab is complicated and expensive. But understanding ...

Salk scientists untangle steroid hormone signaling in plants

...to reach light or strengthen stems. Exploiting its potent growth-promoting properties could increase crop yields or enable growers to make plants more resistant to drought, pathogens, and cold weather. Unfortunately, synthesizing brassinosteroids in the lab is complicated and expensive. But understanding ...

Gene linked to rare disease activates fat breakdown

...er said. "The discovery that CGI-58 acts as a very potent activator offers a new picture of how stored fat is broken down in adipose and other tissues." The finding solves a puzzle first raised in 2001 with the discovery that CGI-58 caused the lipid storage disease CDS in some patients, Zechner said. The s...

Study provides new understanding of spontaneous hybridization

...st time that adaptive trait introgression can be a potent evolutionary force, broadening our view of the mechanisms by which populations adapt to their environments," explain the authors. ...

Gene therapy injected into the brains' of mice with Huntington's disease

...ssion in newly diagnosed HD patients by delivering potent trophic factors with effects that are long-term and non-toxic." "If these results can be replicated in HD patients, it would represent a significant advance in the treatment of this tragic disease", agreed Dr. Jeffrey Ostrove, President and CEO of ...

Microbes transform 'safest' PBDEs into more harmful compounds

...p making and selling penta-BDEs and octa-BDEs, two potent forms of PBDEs linked to health problems in animals. Deca-BDE, the most commonly used form of PBDE, remains on the market because it is considered more stable and less readily absorbed into the body, Alvarez-Cohen says. Laboratory studies, however, h...

Natural vitamin E tocotrienol reaches blood at protective levels

...t another natural form of vitamin E surfacing as a potent neuroprotective agent in repeated Ohio State University Medical Center studies is tocotrienol, or TCT. This form, while not abundant in the American diet, occurs naturally in palm oil; this vegetable oil is increasingly used in prepared foods beca...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...atured on the cover of the journal, demonstrates a potent delivery system for short interfering RNA (siRNA) to attack cancer, says senior author Anil Sood, M.D., associate professor in the Departments of Gynecologic Oncology and Cancer Biology at M. D. Anderson. "Short interfering RNA is a great technolo...

Protein clue to tailor-made antibiotics

...ing protein antibiotics called colicins, which are potent toxins. The research led by Professor Colin Kleanthous has discovered a critical element in the mode of action of a class of colicins (so-called DNases) that kill cells by destroying their DNA. Though most proteins have a folded structure, DNase...

Research reveals control of potent immune regulator

A new study reveals how the production of a potent immune regulator called interferon gamma (IFNg) is controlled in natural killer (NK) cells, immune cells that typically defend the body against cancer and infections. IFNg, produced by NK cells and other cell types, plays a critical role in killing...

First human study confirms that immune cells can be a primary cause of bone loss in gum disease

...'s gingival tissues were functionally sufficiently potent to induce bone destructive cells (osteoclasts) in a laboratory culture system, in spite of the elevated presence of B and T lymphocytes. Since it has never been reported that any bacteria per se invade and resorb bone independent of osteoclast activa...

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