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Tag: "potent" at biology news

Targeting tumors the natural way

...o the alpha-Gal on the organ's cells, unleashing a potent immune response that caused immediate organ rejection. But true to natural cell recognition, the immune response occurs only when clusters of many alpha-Gal molecules are present for anti-Gal to bind with. Armed with this knowledge, Kiessling's gr...

Honeydew honeys are better antioxidants than nectar honeys

...dea about which honeys are likely to have the most potent antioxidant properties,?says Pérez....

Plants do not emit methane

...t terrestrial plants may be a global source of the potent greenhouse gas methane, making plants substantial contributors to the annual global methane budget. This controversial finding and the resulting commotion triggered a consortium (2) of Dutch scientists to re-examine this in an independent study. Repo...

Magic Beans -- Anti-obesity soya could help prevent diabetes

...archers has shown that black soya may be even more potent in rats, and also prevents weight gain (Journal of the Science of Food and Agriculture, February 2007 DOI: 10.1002/jsfa2808). The researchers, led by Shin Joung Rho at Hanyang University, Seoul, allowed 32 rats to gorge on a fatty diet, supplemen...

Reversing cancer cells to normal cells

...testicular cancer) regain the ability to express a potent embryonic morphogen like Nodal, the presence of the Nodal and the signals it sends and receives appear to play a key role in tumor cell plasticity and progression. Most noteworthy, Dr. Hendrix’s team’s also has shown that inhibition of Nodal sig...

Gladstone investigators identify a new protective action for the powerful anti-HIV factor, APOBEC3G

... CD4 T cell activation, we could both preserve the potent anti-HIV effect of the small form of A3G and the protective function of the large A3G complex against select mobile genetic elements," Greene said. Gladstone scientists are now exploring various ways to achieve this desired balance. ...

Growth factor stimulates rapid extension of key motor neurons in brain

...nts to living mammals. "The role of IGF-1 as a potent and specific enhancer of CSMN axon growth is highly relevant to our understanding of this critical population of neurons. These findings are a first step that may someday lead to ways of treating the neuronal degeneration of diseases like ALS, regen...

'Super' enzyme may lead way to better tumor vaccines

...val," he said. Then they sought to develop a more potent form of Akt1 that would enable the dendritic cells...atory, they found that the "super" Akt1 also has a potent effect on human dendritic cells as well, although it has not been used to treat people yet. He ex...

Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses

..., when turned on by so-called ghost parasites, the potent inflammatory response is medically very difficult to control. Researchers say that although chitin, a rigid chemical compound common to fungi, insects and roundworms, is not naturally found in the human body, the presence of its corresponding enzym...

Progress made in HIV vaccine development

...of anti-vector immunity. However, DNA may be less potent than vector-based gene delivery strategies. Replication-defective rAd5 has the advantage of targeted, efficient gene delivery and high potency, but may be susceptible to anti-vector immunity," said Graham. Both vaccines were tested in healthy unin...

A key antibody, IgG, links cells' capture and disposal of germs

... phagosomes that corral invading pathogens and the potent lysosomes that eventually kill off the germs. The research, by Axel Nohturfft at Harvard University and colleagues at Harvard, Massachusetts General Hospital, and the Massachusetts Institute of Technology, appears this week in the Proceedings of the...

Scientists discover toxin that causes gastro disease

Australian scientists have identified a highly potent toxin that causes severe gastrointestinal illnesses, including food poisoning. The toxin, produced by certain strains of E. coli bacteria, has been found to be responsible for an outbreak of haemolytic uraemic syndrome, a dangerous disease that cau...

A new target for painkillers

...effect," the researchers wrote. RgIA was such a potent pain reliever that "about 10 billionths of an ounce reversed the hypersensitivity to pain," McIntosh says. Vc1.1 had a similar effect ?replicating studies by other researchers ?allowing rats with sciatica to tolerate touch with greater pressure. ...

Research holds promise for herpes vaccine

...y unable to cause disease, but is still remarkably potent as a vaccine," Halford said. In a human vaccine, the genetic instructions for ICP0 would actually be removed, creating an "attenuated," or weakened virus. The rest of the herpes simplex virus' genetic code would remain intact. Measles, mumps, rube...

Molecular structure reveals how botulinum toxin attaches to nerve cells

...to botulinum neurotoxins, which are among the most potent toxins known. These neurotoxins are produced by Clostridium botulinum, a bacterium found in soil and food. In the body, the toxins bind to and enter neurons, interfering with nerve transmission and disrupting the communication between the nerve and m...

Antioxidant protects against lung damage in silicosis

... of silicosis. In their mouse studies, hemin, a potent inducer of HO-1, suppressed acute inflammation after silica exposure, whereas zinc protoporphyrin, an inhibitor of HO-1, accelerated the development of silicosis lesions. ...

Caterpillars tell us how bacteria cause disease

...ce genes, which ordinarily might be masked by more potent factors (when dealing with the whole bacterium), but by using insects instead it will also help reduce the number of mammals, such as rats and mice, needed in future genomics research. It also provides a safer method for researchers working with dang...

Therapeutic role found for carbon monoxide

...splant surgery or balloon angioplasty, CO provides potent protective effects against organ rejection or blockage of the carotid arteries. But, with these latest findings, explains senior author Leo Otterbein, PhD, it now appears that carbon monoxide can also be used to treat and reverse existing disease. ...

Gene therapy for hereditary lung disease advances

... animal studies to be close to a thousandfold more potent at making protein," Flotte said. "That's very encouraging to us. So the next trial, which has already begun, is to use the new version of the virus and take patients through a similar range of doses, in a very similar scheme, and see if we can mainta...

Study finds the air rich with bacteria

...remia, also known as rabbit fever. This especially potent bacterium is a possible candidate as a bioterror weapon. But it's also very common. Tularemia has been reported in all U.S. states except Hawaii. This natural background can confound the detection of a terrorist attack and trigger false alarms. The t...

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