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Tag: "pooled" at biology news

Genetic roots of bipolar disorder revealed by first genome-wide study of illness

...ly. The genetic material of the healthy group was pooled and scanned separately, again at a fraction of the cost of individual scans. The researchers then zeroed in on the gene variations that occurred more often in the people with bipolar disorder and examined them individually. An important issue in ...

Sleep quantity affects morning testosterone levels in older men

...es of 64 and 74. Three morning blood samples were pooled for the measurement of total and free testosterone. In addition to overnight laboratory polysomnography, wrist activity monitoring for six-to-nine days were used to determine the amount of nighttime sleep of the participants in everyday life setting...

No-scalpel vasectomies by skilled surgeons may speed recovery

...gely because results from the studies could not be pooled for analysis. "From the results of the review, we would agree that the no-scalpel methodology is the preferable method to use, as it has lower rate of adverse events," Cook said. "But the no-scalpel technique requires more training and a higher le...

Pooled data examines if SNPs add to breast cancer risk

... analyzed by at least three of their studies. They pooled data from all studies for each SNP and assessed how frequently the genetic change occurred in breast cancer patients compared to controls. The authors found that five of the SNPs might be linked to breast cancer risk (with borderline statistical si...

Surprising symbiosis: Glassy-winged sharpshooter eats with friends

...her bacterium, S. muelleri. Sure enough, when they pooled the bits of sample DNA that came from S. muelleri, the team found all the essential amino acid synthesis pathways. "When doing this type of forensic metagenomics, some scientists suggest you can just analyze the whole system as one unit--a so-calle...

A single sugar found responsible for an antibody's ability to treat inflammation

...ntibodies made from human plasma that contains the pooled antibodies from thousands of people, and is only FDA-approved to treat a few assorted conditions; nonetheless, practitioners have used it off-label with varied success in patients with lupus, arthritis and asthma, among other autoimmune disorders. In...

Molecular DNA switch found to be the same for all life

...hila study. Once we compared notes, we immediately pooled forces. When we subsequently were able to dock our bacterial model into a region of their eukaryotic structure, it solidified the evolutionary and functional similarities between the two mechanisms." For the E.coli study, Berger and his team util...

When the going gets tough, slime molds start synthesizing

...ion that the Noel lab wanted to hear. The two labs pooled data and now publish their work as one, very complete story while continuing to collaborate on the chemical diversity found in this fascinating organism that crawls around on the forest floor. Says Noel, who is a professor in the Jack H. Skirball C...

Scientists force viruses to evolve as better delivery vehicles for gene therapy

...their capsids, they introduced them to blood serum pooled from rabbits immunized against AAV, and thus conta... than a year. He is pursuing experiments now using pooled human blood serum. "This virus is kind of a gift from nature, a very safe and efficient virus, but ...

Past illegal blood donation in China linked to hepatitis C virus infection

...blood donation facilities in rural China illegally pooled blood and reinfused compatible red blood cells to permit more frequent donations. Although government action has markedly curtailed such practices since the late 1990s, blood collection and banking methods in such settings still need to be monitored ...

Any exposure to tobacco smoke during pregnancy is risky

... blood samples from newborns. Dr. Grant's analysis pooled the studies' data, looking for frequency of induced mutation as well as the resulting molecular spectrum of mutations. In particular, the new analysis redefines the "non-smokers" used as controls to consider their second-hand exposure to tobacco smok...

Researchers Find New Technique To Identify Fetal Genetic Material From Amniotic Fluid

...iotic fluid. The control group in this study was 6 pooled amniotic fluid samples from women at 17 weeks' gestation who were undergoing amniocentesis (removal of amniotic fluid to test for hereditary diseases and congenital defects in the fetus). "After extraction from the normally discarded fraction of amni...

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