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Tag: "polymers" at biology news

UCF nanoparticle offers promise for treating glaucoma

... makes them less abrasive than some of the complex polymers now used in most eye drops. Seal and his team created a specialized cerium oxide nanoparticle and bound it with a compound that has been shown to block the activity of an enzyme (hCAII) believed to play a central role in causing glaucoma. The ...

Biodegradable microspheres deliver time release vaccines, stimulate different immune response

...chicken pox. "The slow release mechanism of the polymers means that vaccines that currently require multiple doses might need only need a single dose in the future," says Wilson-Welder. Secondly, the finding that vaccine adjuvants can elicit a CMI provides hope for vaccines against intracellular diseas...

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice

...onoclonal antibodies. The bioprobes are cloaked in polymers and sugars that render them nearly invisible to the body's immune system. DeNardo and her colleagues infused trillions of the probes -- more than 10,000 can fit on the end of a straight pin -- into the bloodstreams of laboratory mice bearing human...

Penn researchers show how nanocylinders deliver medicine better than nanospheres

...ny cylindrical nanoparticles composed of synthetic polymers to deliver the anticancer drug paclitaxel to a human lung tumor tissue implanted in mice. The cylinders have diameters as small as 20 nm and lengths approaching the size of blood cells. The paclitaxel shrunk the tumors and, because the cylinders rema...

McBride shows DNA detective work with paper-eating bacteria that 'glide'

...s that motility and digestion of some carbohydrate polymers may be connected in both gliding microbes." McBride and his students have used F. johnsoniae to study the motility of gliding bacteria for more than a decade. They cloned "mutants" of F. johnsoniae that are unable to move, and then attempted to "r...

Exploring the molecular origin of blood clot flexibility

...This is among the most extensible, or stretchy, of polymers that anyone has ever found," says Weisel. "But, how is the stretching happening at a molecular level? We think part of it has to be the unfolding of certain parts of the fibrin molecule, otherwise how can it stretch so much?" Previous research fro...

Applied scientists create wrinkled 'skin' on polymers

...loping wrinkled hard skins on the surface areas of polymers using a focused ion beam. By controlling the direction and intensity of the ion beam, the researchers literally sculpted patterns on flat areas of polydimethylsiloxane, a silicon-based organic polymer (more commonly known as the primary ingredient in...

New synthetic self-assembling macromolecules mimic nature

...y results of this study suggest that these charged polymers self-assemble by like-charge interactions similar to such natural polymers as DNA," said Turner. "The stable self-assembled structures could have potential applications in dru...

Ultrathin films deliver DNA as possible gene therapy tool

... nanoscale films composed of DNA and water-soluble polymers that allow controlled release of DNA from surfaces...e cells, so Lynn constructs his films with special polymers designed to bundle the genes into small tight packages that cells can import. Once inside, the gene...

Widely used iron nanoparticles exhibit toxic effects on neuronal cells

...tics. The researchers also studied long protein polymers inside the PC12 cells that make up the cytoskeleta...organized microtubules and microfilaments, protein polymers involved in cell motility and cell shape. "It's worth noting that neither iron oxide nanoparticle...

Researcher examines polymers created with poultry feathers

Biodegradable polymers created from poultry feathers may add value to the...equirements. He is investigating the properties of polymers created from poultry feather keratin. The protein, keratin, is a major component of hair, nails, and...

Carnegie Mellon scientists use 'green' approach to transform plastics manufacturing

...ed process that allows the production of specialty polymers for coatings, adhesives, lubricants, cosmetics, el.... But Matyjaszewski says large-scale production of polymers by ATRP has been limited because ATRP previously required a high concentration of copper catalyst th...

Scientists find new way to manipulate DNA

...ch of what scientists previously thought about why polymers break when subjected to strong flows, such as wave...omolecular Science and Engineering Program. Broken polymers don't function as intended, and if scientists don't know what causes them to break, they can't keep ...

What's next for gene therapy? Plastic

...demonstrated that the topology of these particular polymers can be changed. "We can control the molecular shape and number of functional end groups," said Long. "We think that topology is important because it can influence the strength of the interaction with DNA and permit efficient release of the DNA for pr...

Nano-devices hold promise for early-stage cancer detection

...ologies such as DNA, semiconductors, nanowires and polymers into "smart systems" on a small chip. The resulting micro-labs could contain miniaturized systems for fluid filtration, DNA extraction, cell processing, imaging, computing, wireless communications, and laser and radiation detection systems. Resea...

Two central mysteries in genome inheritance solved at UCSD

...nding on the species, requires specialized protein polymers called microtubules. "After the genome is replicated, microtubule polymers build a spindle-shaped structure whose two ends collect precisely half of the duplicated genome befo...

Finding the right mix: A biomaterial blend library

...ractice, many biomaterials are made from blends of polymers to achieve specific material properties. Optimizing the blend composition is often a difficult and time-consuming task. As the blends gained a higher or lower proportion of a respective material, the cells around them react by changing shape, ultimat...

With record resolution and sensitivity, tool images how life organizes in a cell membrane

...erizing hard materials, such as rocks, space dust, polymers and nanoelectronics. But in the last five years, biologists have become interested in employing it to characterize components of biological samples on a length scale of 100 nanometers or less. ''There's currently no way to do that,'' Boxer said. ''Y...

MIT engineers probe spiders' polymer art

...made from polymers. The proteins in our bodies are polymers made from amino acids. From the Greek for "many" and "units," polymers are long linked chains of small molecules. They can be flexible or stiff, water-soluble or insoluble...

Triple threat polymer captures and releases

...perature. Wooley mixes two normally incompatible polymers -- a hyperbranched fluoropolymer and a linear poly...ey says that the results of her research with the polymers ?the promoted release, the anti-fouling application ?are "strange, if not weird, but there is so muc...

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