Deep thinking: Scientists sequence a cold-loving marine microbe
... polyunsaturated fatty acids that resist freezing, polyester compounds that offer extra energy reserves, protective solutes inside cells, and ordinary enzymes altered to function in chilly seawater. "Our goal was to compare C. psychrerythraea to a variety of bacteria that live at different optimal temperature...Chemical tests of cell growth enter third dimension
...hey grow; inside the FBB, they cling to strands of polyester fibers. For the first of the two new technologies, Yang took the basic concept behind the FBB and combined it with laboratory testing methods that normally only grow cells in two dimensions. Such tests are normally done on cells in trays containing...Soft-cell approach cuts animal tests
...cytotoxic effects. The cells are grown on a porous polyester membrane inside a small diffusion chamber and then exposed to selected toxic air pollutants. After as little as one hour's exposure, they can study cell growth and metabolism, and a range of routine toxicological endpoints. Importantly, the toxic m...University of Pittsburgh School of Medicine researchers develop 'off-the-shelf' vascular grafts
...ying, MDSCs inside a biodegradable porous, tubular polyester urethane scaffold using a rotational vacuum seeding device. After culturing their vascular constructs for seven days, the investigators then implanted them in the abdominal aortas of rats eight weeks before performing tests to determine how well ...