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Tag: "poised" at biology news

Technology reveals 'lock and key' proteins behind diseases

... cells in our bodies contain transporters that are poised in cellular membranes and act as ‘gatekeepers?to allow the entry of certain substances, like nutrients, into the cell and promote the export of other substances, like toxins, out of the cell," says Professor Igor Stagljar, Department of Medical Genet...

Nanotechnology shows promise as next wrinkle fighter

...lasers to Botox injections ? and nanoparticles are poised to join the war by warding off dreaded buckles in human skin. Ilsoon Lee, an assistant professor of chemical engineering, along with Ph.D. student Troy Hendricks, published an online article in the American Chemical Society's Nano Letters in Decemb...

Columbia University licenses next-generation DNA sequencing technology

...olecular biology and engineering expertise. We are poised to offer a simple, cost effective platform that will enable many researchers and clinicians to use this next-generation DNA sequencing technology in their own laboratories." Dr. Ju is a prolific inventor of new technologies for applications in geno...

Getting to the heart of the heart

...just 1 percent of the cells in the dish) that were poised to begin developing along a cardiac pathway. The presence of these cardiac progenitors was indicated by a green fluorescent protein, which lit up when a gene called Nkx2.5 was activated. Orkin and Wu then showed that these cells further differentiate...

Ozone recovering, but unlikely to stabilize at pre-1980 levels, says study

...n step occurs in the nucleus where BES1 is already poised for action. Once released from BIN2 inhibition, BES1 associates with itself and other regulatory factors, and this modified form of BES1 binds to DNA, activating scores of target genes. Referring to the work of Vert and other members of the brassino...

Salk scientists untangle steroid hormone signaling in plants

...n step occurs in the nucleus where BES1 is already poised for action. Once released from BIN2 inhibition, BES1 associates with itself and other regulatory factors, and this modified form of BES1 binds to DNA, activating scores of target genes. Referring to the work of Vert and other members of the brassino...

DOE publishes research roadmap for developing cleaner fuels

...llulose to ethanol. DOE's Genomics: GTL program is poised to help do just that." The roadmap responds directly to the goal recently announced by Secretary of Energy Samuel W. Bodman of displacing 30 percent of 2004 transportation fuel consumption with biofuels by 2030. This goal was set in response to the...

Think fast! Rice undergrad unlocks nerve speed secret

...that held the pre-positioned vesicle in check, but poised for release. These new studies clearly show that the brake is a protein called complexin." Rice's study, which was conducted in McNew's lab, largely by undergraduate Johanna Schaub, involved in vitro experiments on a synthetic and highly controlled...

Production of key Alzheimer's protein monitored for first time in humans

Science is now poised to answer an important and longstanding question about the origins of Alzheimer's disease: Do Alzheimer's patients have high levels of a brain protein because they make too much of it or because they can't clear it from their brains quickly enough? ...

Mayo Clinic researchers challenge sepsis theory

...th sepsis? Dr. Brunn explains, "Our bodies are not poised to respond to sepsis. Our bodies are held in check by the fact that this molecule-receptor system is constrained in its activity. What causes sepsis -- and the syndrome like sepsis that can happen in cancer or trauma or in response to drugs -- is tha...

Two NIH initiatives launch intensive efforts to find roots of common diseases

...edical research over the past 10 years. We are now poised to combine what we have learned from years of population studies, with newly available technologies, developed with NIH support. These technologies reduced the cost of genotyping by more than 100-fold, making such a comprehensive effort affordable. E...

Common enzyme is a key player in DNA repair

...nism, they believe, the same specialized enzyme is poised to patch over a certain kind of blemish so that it does not permanently damage the genome. The DinB gene and its protein product were first discovered in Walker's lab in 1980, long before scientists knew anything about translesion polymerases. Then...

NJIT engineer poised to take stem cell research a step forward

...ls forward and, with her latest two grants, she is poised to take it yet another step. "Treena has all the earmarks of a technical superstar," says Jaffe, her partner on the spinal cord research. "She's at the leading edge of modern biology and if anyone can take stem cell research forward, she can." ...

Novel molecular 'signature' marks DNA of embryonic stem cells

...the activating influence appears to keep the genes poised for later activity. "For genes, this is equivalent to resting one finger on the trigger," said Stuart Schreiber, an author of the Cell paper, the director of the Chemical Biology program at the Broad Institute, and professor at Harvard University. "T...

Picking apart how neurons learn

...nt mouse populations in hand, the research team is poised to further dissect the molecular mechanisms behind learning. "The next step is to determine whether LTD is crucial for motor learning, the so-called holy grail in the field," says one of the study's co-first authors, Jordan Steinberg, an M.D., Ph.D....

Open Source Biotechnology alliance for international agriculture

...e countries are growing powerhouses of innovation, poised to play lead roles in the next generation of biological problem solving. The Patent Lens will also develop analyses and foster the capacity in the developing world to create patent maps of the key emerging technologies that could be constrained by c...

Report focuses on challenges to unlocking future promise of vaccines

...ous agents that are relatively rare today, but are poised to emerge by either natural or terrorism-related means, like avian influenza, West Nile virus, and botulism toxin. According to the report, research and development must continue the progress of the past to address those diseases that have eluded th...

New type of rejection blocker protects kidneys after transplant

...gan as foreign and to signal production of T-cells poised to destroy it. A second, co-stimulatory signal is required before the T-cells attack the kidney. By blocking this second signal, belatacept prevents destruction of the kidney without suppressing the immune system's response to viruses and other patho...

Biologists determine genetic blueprint of social amoeba

...th a fruiting body composed of a stalk with spores poised on top. This increases its utility in a variety of studies. "An organism's relationship to humans depends on how related the proteins are that are found in the two cell types," says Kuspa. "You can make direct analogies, or you could learn general p...

FDA approves more generic AIDS drugs

...m disappear. The result is that the system remains poised for an immediate response to bacteria and other attackers. "By controlling disappearance of resisting proteins, RAR1, HSP90 and SGT1 control whether or not the plant is about to recognize that it is under pathogen attack," Holt said. "So the emergin...

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