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Tag: "points" at biology news

A case of mistaken molecular identity

...ne of many ideas to explore now. The research also points out that we need new drugs or vaccines to stop the parasite, and at a social level, it stresses the need to improve living conditions of Chagas patients, particularly those living in rural areas." ...

Common molecular 'signature' identified in solid tumors

...h keep potentially malignant cells in check. Croce points out that miRNA activity is tissue-sensitive, meaning some miRNAs may be overexpressed, or "turned on" in some of the cancers while in others they are underexpressed, or "turned off." In the six types of cancer in the study, the majority (26) of the...

New weapon in battle against osteoporosis

...are not destined to have problems. However, as she points out, "Women with this mutation have a three-fold higher risk of osteoporosis." The results show not only that the CB2 receptor is essential for the maintenance of a normal bone mass; they also open up completely new possibilities for therapy: "In ma...

Tandem transcripts team together

...phenomenon challenges our very concept of a gene," points out Guigó. "The 'one gene, one protein' rule has been fundamental to molecular biology. However, as we deepen our understanding of the eukaryotic genome, a picture emerges that challenges this paradigm ?not a picture in which the sequences in the g...

BioMed Central launches Biology Direct

...rocess gives the author the opportunity to discuss points raised directly with the reviewers, and to revise their manuscript as much or as little as they wish, according to the suggestions or criticisms of the reviewers. Ultimately, reviewers can express reservations about the manuscript but publication can...

Drug-resistant bacteria patterns in intensive care units changing nationally

...lates were MRSA, an increase of about 3 percentage points per year. Despite the increase in MRSA prevalence, there was also a decrease in MRSA that was resistant to multiple drugs. The researchers hypothesize that the influx of MRSA strains from the community might have replaced those multidrug-resistant ...

One in 14 men having a heart attack drive themselves to hospital

...urs to get there, compared with 1.8 hours for men" points out Dr O'Donnell. A previous paper by the team, on what happened to the same patients when they actually arrived at the Irish hospitals, found that women waited longer than men to be admitted and treated. "This means that women not only took longer...

New test to detect rare proteins in blood

...to current technologies. The researchers say this points to FACTT's broad applicability and compatibility with current high-throughput testing technology. This, in turn, will facilitate the detection of rare markers and not-so-rare targets from much smaller sample volumes, as well as aid in monitoring mark...

High-resolution light microscope reveals the fundamental mechanisms of nerve communication

...mical messenger molecules to synapses, the contact points between nerve cells, enabling nerve signals to pass between cells. Their contents are released at the synapse when the vesicle membranes fuse with the membrane of the nerve cell. Previously it was unclear whether the proteins sticking in the vesicle ...

Salmonella caught red-handed

...k against bacteria. There are hundreds of possible points of attack, according to genome analysis and labora... special protein databanks and identified possible points of attack for antibiotics. Bumann and his team then examined what role these proteins play in a Sal...

Weizmann Institute suggests that immune cells help to maintain cognition and brain cell renewal

...ning and memory abilities in adulthood. Schwartz points out that the role of the autoimmune T cells is not to affect the level of intelligence or motivation, but rather, to allow the organism to achieve the full potential of its brainpower. "These findings," she says, "give a new meaning to 'a healthy min...

Scientists discover that widely available drug also helps fight kidney disease

...ents, this result is highly encouraging because it points in the right direction," said Weimbs. It shows, for the first time, a connection between polycystin-1 and mTOR, and strongly suggests that rapamycin may be a promising drug for treating PKD, explained Weimbs. "The fact that rapamycin is already clin...

Tiny RNA molecules fine-tune the brain's synapses

... microRNA affects the development of synapses ?the points of communication between brain cells that underlie learning and memory. The findings appear in the January 19th issue of Nature. "This paper provides the first evidence that microRNAs have a role at the synapse, allowing for a new level of regulatio...

Waking a sleeping virus

...ocking it would be much better." To identify weak points of ZEBRA as potential drug targets Morand and Carlo Petosa from Müller's group created a high-resolution map of the protein's structure. Using the unique technology "platforms" that EMBL and the IVMS have set up in partnership with the neighbouring i...

Discovery of new molecular tools for biosynthesis could lead to advances in use of pectin

... until the 21st century, been slow to unfold." He points out the large number of pectin uses, from food production to cancer prevention and treatment, and notes that more information on the process of manipulating the quality and quantity of wall polysaccharides is crucial and badly needed. "The work [des...

World's pledge to halve hunger by 2015 looks like empty promise

... relieve immigration pressures. Pinstrup-Andersen points out that developing nations spend, on average, 0.5 percent of the value of their agricultural output on research when they should be spending 2 percent. By comparison, the United States spends 5 percent. Since 70 to 75 percent of the world's poor an...

Researchers use dirt to stay one step ahead of antibiotic resistance

...tion andImmunity. "Dr. Wright's exciting discovery points to the fact that innature, bugs in the soil survive in a very hostile environment. They dothis by developing resistance to the antibiotics produced by other soilbacteria. Understanding this process opens up a new avenue for findingnew therapies to pr...

A surprising pair of proteins help make healthy eggs

...important piece of the reproduction puzzle, and it points to possible drug targets for treating infertility and ovarian cancer. "Thousands of women in this country undergo fertility treatments each year and some have no idea why they can't get pregnant," said Richard Freiman, an assistant professor in the ...

For one Stanford doctor, the beat goes on during open-heart surgery

...wn positive experiences with the technique, Ihnken points to a recent report in the new journal Innovations, which presents an analysis by an international group of doctors of more than 150 previous studies of the procedure. It found that the beating-heart technique is as safe as conventional heart surgery...

Typhoid fever led to the fall of Athens

...lected from teeth from an ancient Greek burial pit points to typhoid fever as the disease responsible for this devastating epidemic. The study appears on the online version of The International Journal of Infectious Diseases (IJID) published by Elsevier on behalf of the International Society for Infectious ...

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