Virginia Tech's System X supercomputer provides super tool for simulation of cell division
...ch algorithm improves the values from the starting points found by the global algorithm." The parallel computer programs can now be used by others for similar problems. "The parameters found for the budding yeast cell cycle model are good until the next scientist invalidates them with new experimental da...Proteins may predict lung transplant rejection
... biomarkers may be better than others at different points of the disease's development. The information could offer inroads to new therapies, said Wendt. Doctors may be able to increase the dose of anti-rejection drugs when the early markers of rejection appear. Or, they may reduce anti-rejection drugs f...Molecular atlas provides new tool for understanding estrogen-fueled breast cancer
...t genes have more than one control region, the map points to about 1,000 genes influenced, to some degree, b.... This allowed the researchers to identify all the points in the genome where binding with the ER takes place. The researchers coined the word "cistrome" to...Male contraception: One door opens, another closes
... for technologies at Seattle-based nonprofit PATH, points to the female condom as an example. "We got funding to design a great female condom that men and women like much better than what's out there," he says. "But now we're ready to do the big clinical trials, and our funders just don't have the money...Global changes alter the timing of plant growth, scientists say
...parate times. Consequences could be significant, points out co-author Loarie: "If plant species overlap more in the future because their timing is altered by global changes, it could lead to decreases in local plant diversity and negatively impact animals that depend on those plants." Satellite images i...Scientists show drug can counteract muscular dystrophy in mice
...phy in mouse models," says Dr. Sartorelli. Yet he points out that the drug is only promoting muscle regeneration ?it is not curing the defect that causes muscle deterioration. Further studies are needed to determine how long the drug works and if it works in larger animals with bigger muscles, such as dogs...Common ancestry of bacterium and plants could be key to an effective new treatment for chlamydia
...ritage, which is not found in most other bacteria, points to a prime target for development of an effective ...ls that is inhibited by penicillin. This discovery points to the likelihood that, if researchers could find an inhibitor for L,L-diaminopimelate aminotransfer...A buffet for early human relatives
... The laser was used to remove samples at various points along the length of the tooth, which is marked by tiny ridges called perikymata. They run parallel to the tooth's crown and represent tooth growth, similar to tree rings. Perikymata are produced under the gums during the animal's juvenile years, when...Robotic whiskers can sense three-dimensional environment
...skers and thus determine the location of different points on the head. A computer program then "connects the dots" to create a three-dimensional representation of the object. The researchers also showed that a slightly different whisker array -- one in which the whiskers were widened to provide more surf......'s high tide mark at Foul Bay near Margaret River, points to the high point of the last major sea level rise. Investigators from the ARC Centre of Excellence for Coral Reef Studies (CoECRS) consider the reef ?the most southerly coral reef yet known ?is a harbinger of what could happen again as global CO2 ...Gene-bender proteins may sway to DNA
...he DNA is able to bend or kink on its own, at weak points created by the transient opening of base-pairs, and that the protein recognizes and binds tightly to the bent DNA conformation." Conclusions by Ansari and her colleagues deviate slightly from the conventional dogma that it is the protein that bend...Sensory feedback during speech: The brain attunes to more than just sound
... altered the path of the jaw's motion at different points during speech, but did not significantly disrupt t...ers were able to manipulate jaw motion at specific points during speaking and were thereby able to specifically target vowel or consonant sounds to study whet...Ebola-outbreak kills 5000 gorillas
... anti-poaching. We need to do both." Walsh also points out that Ebola has the potential to quickly destroy years of ecotourism investment. For example, Bermejo’s gorilla habituation program at Lossi was set up in the mid-1990’s in collaboration with the European Union’s Ecosystem Forestiere d’Afrique Cen......ate a genetic map that can distinguish between two points 0.37 cM apart in HS and 0.45 cM in RI. Using their maps, Shifman and colleagues then investigate recombination rates of various genes by comparing physical and genetic distances for each strain. On average, the recombination rate was 0.63 cM per m...Longer-lived rodents have lower levels of thyroid hormone
... animals were of different ages, but at comparable points in their life spans. For example, the mole-rats, which live 28 years, were two years old. The mice, which live about 3.5 years, were six months old. The study determined the levels of T3 and T4 for each animal. T4 levels vary the most T4 leve...Stem cells found in adult hair follicles may provide alternative to embryonic stem cells
...the injured spinal cord of mice. Dr. Sieber-Blum points out that the cells may also be useful to treat Parkinson's disease, multiple sclerosis, Hirschsprung's disease, stroke, peripheral neuropathies and ALS. Certain defects of the heart, and bone defects (degeneration, craniofacial birth defects) could a...Plant-derived molecules, genetic manipulation point to future chemoprevention methods
...for these compounds in preventing lung cancer, and points to the need for clinical trials to test their effectiveness in humans. The triterpenoid, CDDO-methyl ester, and the rexinoid, LG100268, synergize in the prevention of mammary tumors in a mouse model of estrogen receptor-negative breast cancer T...Pattern of human Ebola outbreaks linked to wildlife and climate
...omprehending the ecology of the disease. Lahm points out that there remain many unanswered questions about Ebola including how the virus spreads within and between mammal species. "Our study provides more pieces of the puzzle, but at the same time it is enlarging the puzzle," she noted. Richard B...Novel regulatory mechanism identified for key tumor suppressor p53
...n to shut down cell division and induce cell death points to why the availability of a repressive mechanism such as the one outlined in the new study might be crucial for cellular survival. "You can imagine that if the p53 protein were present at all times and able to bind to DNA, cells would be in big tr......icians have a convenient and effective way to earn points towards maintenance of certification, improve their practice, and, most importantly, enhance the quality of care they provide." ASH is developing additional measures in the area of multiple myeloma to be released within the next several months. In a...