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Data published in PNAS show antibodies can be made 10 times more toxic to cancer cells

Engineering the "Fc" region of monoclonal antibodies (mAbs) increases their toxicity to cancer cells, potentially improving the utility of targeted cancer therapies, according to research conducted at Xencor, which will be published in the March 14 print issue of the Proceedings of the National Academy of Sciences (PNAS). . Monoclonal antibodies have important advantages over chemotherapy and sm...

PNAS study reveals why organs fail following massive trauma

Massive trauma, say from a sabertooth tiger attack, meant immediate death for the primitive human. Modern man is more likely to survive severe injury caused by a car crash, gunshot or fall thanks to high-tech emergency medicine. Unfortunately, the body does not know what to do when it survives an injury that would have been fatal until recently in human evolution. Nearly one third of the time, m...
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(Date:9/18/2014)... and nitrogen comprise all spheres of our planet. ... caused imbalances and perturbations that resulted in increases ... result in climate changes which influence the complex ... atmosphere. Understanding these feedback mechanisms has become an ... during the past three decades. , In parallel, ...
(Date:9/18/2014)... the fish world, are the ideal animal in which ... moved from the ocean into tens of thousands of ... changing their skeleton to adapt to the new environment. ... sticklebacks now have turned up one of the genes ... change in that gene,s regulation in a freshwater population ...
(Date:9/18/2014)... spend their entire lives nestling in the protective tentacles ... babies they sometimes travel hundreds of kilometres across the ... reef fish has been predicted, this is the first ... distant populations has been observed. , Dr Steve Simpson, ... the University of Exeter, and colleagues from the Australian ...
Breaking Biology News(10 mins):Greenhouse gas research enters a new era 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 2Counting fish teeth reveals regulatory DNA changes behind rapid evolution, adaptation 3Expedition finds Nemo can travel great distances to connect populations 2Expedition finds Nemo can travel great distances to connect populations 3
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(Date:9/19/2014)... WASHINGTON (Sept. 19, 2014) Shahram Majidi, M.D., ... at the George Washington University School of Medicine ... the American Heart Association to study the presence ... with intracerebral hemorrhage (ICH). , "According to epidemiological ... percent of all strokes, but is the least ...
Breaking Medicine News(10 mins):Health News:Brain Structure Might Help Predict Risky Behavior 2Health News:Alliance for Bangladesh Worker Safety and NFPA Sign Memorandum of Understanding to Strengthen Safety in Bangladesh Garment Factories 2Health News:Alliance for Bangladesh Worker Safety and NFPA Sign Memorandum of Understanding to Strengthen Safety in Bangladesh Garment Factories 3Health News:OC Healthcare Agency StudioPMG Partners with The Raw Beauty Project ™ NYC 2014 2Health News:Pro Ace Now Provides Heating, Air Conditioning, Plumbing & Electrical Services under One Roof 2Health News:GW researcher receives grant to study brain swelling following bleeding in the brain 2
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