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Tag: "plus" at biology news

Buckyballs boost antibody's chemotherapy payload

...ial to carry multiple drug payloads, such as Taxol plus other chemotherapeutic drugs," said Rice's Lon Wilson, professor of chemistry. "Cancer cells can become drug resistant, and we hope to cut down on the possibility of their escaping treatment by attacking them with more than one kind of drug at a time...

Novel therapy combinations gain ground in treating hepatitis

...400 mg/d, 800 mg/d or dose-ramping 400 to 800 mg/d plus pegIFN, or pegIFN with ribavirin as a control grou...cacy of daily doses of CIFN (consensus interferon) plus ribavirin (RBV) versus pegIFN (pegylated interferon alfa 2a) plus RBV for 72 weeks in patients with ...

Injection may prevent infertility in men receiving cancer chemotherapy

...vided the mice into four groups ?Taxol only, AS101 plus Taxol, AS101 only, and a control group. After 30 days they were euthanized and their testes examined and weighed. The researchers found that a single dose of Taxol had induced significant testicular weight loss compared with the control group. A...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

...or were empty. Some mice received siRNA liposomes plus the chemotherapy docetaxel. Mice receiving the FAK-silencing liposome had reductions in mean tumor weight ranging from 44 to 72 percent compared with mice in the control groups. Combining the FAK-silencing liposome with docetaxel boosted tumor wei...

Cells use mix-and-match approach to tailor regulation of genes

... on single transcription factor-gene associations, plus other experimental evidence that indicates that that gene regulates a second gene. To enlarge the scope of the model further, Ideker's group also incorporated other previously discovered transcription-factor interactions and related genetic results....

The molecular post office inside the cell

... "machine" is made up of a single active ribosome, plus a special signal recognition protein and a matching receptor. The scientists have shown that when the three proteins interact, certain areas open up on the ribosome, which allows the ribosome to dock onto another complex. The later complex, which is ...

Scientists take 'snapshots' of enzyme action

...oduce crystal structures of the enzyme, the enzyme plus its cofactor, and the enzyme plus the cofactor plus the compound to be oxidized (the substrate). "These crystal structures give step-...

Statins stop hepatitis C virus from replicating

...when the statin was used alone. Again, fluvastatin plus interferon exhibited the strongest effect. "We clearly demonstrated that co-treatment of interferon and fluvastatin was an overwhelmingly effective treatment," the authors report. This combined therapy was more effective against HCV RNA replication t...

Iowa State researchers improving plastics made from corn and soy proteins

...l also work to characterize the plastics' strength plus its thermal and mechanical properties. Working with the two companies should help move all that work ahead, Kessler said. "Collaborating with these companies will be useful," he said. "And we hope it will help us come up with other ideas."...

Vaccine combined with short-term postexposure antibiotics protects monkeys from inhalational anthrax

...ll 10 monkeys that received 14 days of antibiotics plus vaccination survived when the antibiotics were discontinued. Thus, postexposure vaccination enhanced the protection afforded by 14 days of antibiotic prophylaxis alone, and completely protected all the animals against inhalational anthrax. "This pr...

Therapeutic role found for carbon monoxide

...he physical interaction between the two cell types plus the ability to generate NO was crucial for the positive CO effects," he says, adding that studies are now underway to determine the mechanism by which CO exposure leads to the increase in NO generation. "Our hope is that CO will find a place in the ...

Quantum dots reviewed -- Could these nanoparticles hold the cure to cancer?

...tions, toxic effects, use in imaging and analysis plus Quantum Dot drug delivery systems. The paper also outlines some early success in the detection and treatment of breast cancer. The paper concludes with a quick look at what the future may hold for Quantum Dots in providing new insights into unders...

Worms produce surprise insight into human fever

...Aballay found a wealth of data on innate immunity plus a surprising insight into another classic metazoan...pathways that encoded immunity effector molecules plus relevant signaling molecules and transcription factors. In fluorescently labeled transgenic worms, ...

SARS: No evidence that any of the treatments worked

...82 2 872 2803 (fax) lseidlein@ivi.int Is DOTS plus a cost effective strategies for treating multidrug-resistant tuberculosis? A research paper published this week in the international open access journal PLoS Medicine evaluated the feasibility, effectiveness, cost, and cost-effectiveness of a DOTS...

Rising ocean temperatures, pollution have oysters in hot water

...ases metabolism and oxygen demand. Temperature plus cadmium = power disruption However, there was no difference in oxygen consumption between the two groups acclimated to 28°C. The researchers concluded that the cadmium-exposed oysters in this group needed more oxygen than the unexposed group, but...

Detailed 3-D image catches a key regulator of neural stem cell differentiation in action

...ic stem cells into becoming specific cell types, a plus for both basic research and potential therapies. "At the moment, the differentiation of stem cells into neurons in a Petri dish is a little bit like a black box and not very efficient," explains co-author Samuel Pfaff, Ph.D., a professor in the Sa...

The power of one: A simpler, cheaper method for cell fusion

It's not easy to make one plus one equal one. But biological engineer Chang Lu has done just that with a new and cheaper method to electrically fuse cells - a vital technology for studying stem cells, creating clones and finding disease antibodies. "The only current method for ...

Gene study shows three distinct groups of chimpanzees

...discontinuous populations," three of common chimps plus the bonobos. Hybrids, those with at least five percent of their DNA from more than one common chimpanzee population were rare, with most of the hybrid chimps born in captivity. "We saw little evidence of migration between groups in the wild," said...

Paleontologists discover new mammal from Mesozoic Era

...leus), the anvil (incus) and the stirrup (stapes), plus a bony ring for the eardrum (tympanic membrane). The mammal middle ear bones evolved from the bones of the jaw hinge in their reptilian relatives. However, paleontologists long have attempted to understand the evolutionary pathway via which these ...

Penn study on olfactory nerve cells shows why we smell better when we sniff

...arch issue of Nature Neuroscience. This finding, plus the fact that both types of stimuli produce reaction in olfactory nerve cells, which control how our brain perceives what we smell, explains why we sniff to smell something, and why our sense of smell is synchronized with inhaling. "The driving f...

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