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Breakthrough System for Understanding Ocean Plant Life Announced

...at base J (beta-D-glucosylhydroxymethyluracil) may play an important role in the gene silencing process be...ion of antigenic variation. If base J does indeed play a role in the gene silencing that enables the trypanosome to change its antigen coating, the discove...

Climatologists discover deep-sea secret

...nce showing that waters in the southern hemisphere play an active role in sudden climate changes. Today's climate in Europe and North America is greatly influenced by the gulf stream. This ocean current carries warm water from the Gulf of Mexico northwards along the Florida coast, eastwards across the At...

Tamoxifen-like drug suggests new ways to selectively block estrogen

... finding indicates that this little-known drug may play an important role in preventing, as well as treating, breast cancer and suggests ways to design new drugs with even more specific effects. In the May 13, 2005, issue of Molecular Cell, researchers from the University of Chicago, Renz Research, Inc.,...

U of T researchers map role of Epstein-Barr virus in cancer

...n coded in the Epstein-Barr virus and suspected to play a role in the development of cancer," says Lori Frappier, professor in medical genetics and microbiology at U of T and senior author of a paper in the April 1 issue of Molecular Cell. "This research shows how EBNA1 interferes with natural cell growt...

Researchers reveal secret of key protein in brain and heart function

...nce in the heart and head, where it is believed to play a role in everything from cardiac contractions to memory creation. Results are published in The Journal of Biological Chemistry. Dale Mierke, associate professor of medical science at Brown, said that knowing how a piece of SAP97 is built is an impo...

Brain Scan Study of Smokers Reveals Signature of Craving

...ts that conditioned responses to sensory cues also play an important role, McClernon said. Brain imaging studies of smokers have found increases in brain activity in response to smoking-related images in areas associated with attention, motivation and reward. However, those studies examined smokers only a...

Cancer drug slows poxvirus in mice

... animal model studies, suggests that Gleevec might play a role in addressing a public health emergency in the event of a smallpox outbreak, Dr. Kalman says. Specifically, Gleevec might be useful as a preventative against adverse effects of smallpox vaccine, enabling clinicians to use the vaccine even in p...

High-powered gene profiles provide clues to genes involved in common form of lung cancer

... in that area is one called p63, which is known to play a role in the ability of skin cells to reproduce. The new finding raises the possibility that adenocarcinoma and squamous cell carcinoma arise from an error in the same cell type and are driven to malignancy by similar genetic routes, the study autho...

Circulating stem cells play small role in lung repair

Circulating stem cells play a minor role in repairing lung damage, according t... that circulating stem cells could be augmented to play a greater role in lung repair ?and people are looking at ways to do that. We found that the bulk of ...

The making and breaking of microtubules

... these molecules also regulate enzyme activity and play a crucial role in controlling microtubule growth. When GTP binds to a particular locus on beta tubulin (the E-site or exchangeable site) polymerization occurs: tubulin dimers pile onto the protofilaments, and the microtubule grows. But through hydro...

Candida albicans Genome Fully Annotated

Circulating stem cells play a minor role in repairing lung damage, according t... that circulating stem cells could be augmented to play a greater role in lung repair ?and people are looking at ways to do that. We found that the bulk of ...

Researchers discover stem cell 'guide' that may be key for targeting neural stem cell treatments

... peptide called prokineticin 2 (PK2), was found to play a key regulatory role for the proper functional in... GPCRs are proteins found in a cell's membrane and play a critical role in transferring signals from outside of a cell to the molecular machinery within the...

Study: Well-known protein helps stem cells become secretory cells

...er. CrebA, or a closely related human gene, might play the same role in certain human cells, too, the researchers say. In juvenile (type I) diabetes, for example, pancreatic cells that normally produce and secrete insulin don't work, and stem cells might be able to help fix that problem, the researchers...

UCR chemist part of team identifying new areas of gene regulation

...istone acetylation, a modification of the protein, play a fundamental role in the regulation of gene activation and repression. The key findings of the current paper were the discovery of this acetylation at the core of the histone, rather than at the proteins' ends, which are where most gene regulation ...

Specialized immune-system B cells play double-barreled role

...ruction. Generally, B-1 cells have been thought to play a major role in the innate immune response -- the type of immunity that offers rapid, generalized responses to infections. Less understood has been any role in adaptive immunity -- in which the immune system develops a long-term immune response to an...

Molecular steps involved in the creation of gene-silencing microRNAs identified

...mall, remarkably powerful molecules that appear to play a pivotal role in gene silencing, one of the body'...plication is that the RNA interference pathway may play a significant role in HIV replication. TRBP has also been identified as a tumor suppressor, which su...

ORNL, UC Berkeley unravel real-world clues to Earth's mysteries

...team, which noted that while microbial communities play key roles in the Earth's bio-geochemical cycles, scientists know little about the structure and activities within these communities. This is because the commonly used artificially cultivated organisms lack the diversity found in nature, so potentiall...

Scripps research scientists identify infertility molecule

...lity problems, which suggests that these receptors play a major role in conception. In the latest issue o...re more than just simple structural elements. Some play significant signaling roles in the cell. LPA belongs to a family of phospholipids known as "lysophos...

Researchers use 3-D imaging system to unveil swimming behavior of microscopic plankton

... square meter of the world's oceans. These animals play a key role in the marine food web as a crucial link between primary producers and predators. The imaging system, Fish TV, uses multibeam sonar to uniquely measure animal movement. The system allowed the researchers to analyze the swimming behavior o...

Evolution of taste receptor may have shaped human sensitivity to toxic compounds

... an attribute that could have come into particular play during periods of expansion into new environments. More broadly, the work contributes to the debate on the mechanisms governing the evolution of chemical sensory perception and on the role of diet as a selective force in human evolution. ...

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