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Tag: "platinum" at biology news

Virginia Tech group adds tools to DNA-targeted anti-cancer drugs

...t binds to DNA inhibiting cell replication. "Using platinum assures that we are activating complexes that are already attached to the target," Brewer said. "The previous systems had an association with DNA but could release, which might result in an impact on other parts of the cell." Because the therapeutic...

Bad aftertaste? New sensory on/off switch may 'cure' bane of artificial sweetener search

...t binds to DNA inhibiting cell replication. "Using platinum assures that we are activating complexes that are already attached to the target," Brewer said. "The previous systems had an association with DNA but could release, which might result in an impact on other parts of the cell." Because the therapeutic...

Six previously blind patients detect light, motion, identify objects with retinal prostheses

...cing those cells with its device, a 4-by-4 grid of platinum electrodes embedded in silicone rubber. The electrodes are wirelessly stimulated through an external controller hooked up to a head-mounted video camera. This study is being conducted under a Food and Drug Administration Investigational Device Exemp...

VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum

...archers reported on the design of a new trinuclear platinum compound and demonstrated that its cellular absorp... neutral cisplatin, as well as other multi-nuclear platinum compounds. The enhanced uptake into cancer cells takes advantage of weak molecular interactions on t...

Mystery solved: Gold's power against autoimmune diseases defined

...MHC class II protein. From there, they found that platinum was just one member of a class of metals, including a special form of gold, that all render MHC class II proteins inactive. In subsequent experiments in cell culture, gold compounds were shown to render the immune system antigen presenting cells ina...

New protein target may advance design of HIV and cancer drugs

...HIV NCp7, can be inhibited when it is exposed to a platinum complex. They observed that when the HIV NCp7 prot...ss, active site displacement, involved design of a platinum drug with higher affinity for the protein peptide backbone, thus eliminating the zinc from its activ...

Sandia researchers discover way to see how a drug attaches to a cell

...l through a new process that produces novel hollow platinum nanostructures. The research will appear as a pap... a new way of producing porous, nanoscopic, hollow platinum spheres by using liposomes as blueprints. (Liposomes are microscopic, fluid-filled pouches that are ...

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